Chercheur

    Jean-Luc Bigras , M.D.

    jean-luc_bigras@ssss.gouv.qc.ca
    Jean-Luc Bigras
    Axe de recherche
    Santé métabolique et maladies complexes
    Thème de recherche
    Santé cardiométabolique et vasculaire: approches génétiques et environnementales
    Adresse
    CHUSJ

    Téléphone
    514 345-4931 #5410

    Fax
    514 345-4896

    Titres

    • Cardiologue, CHU Sainte-Justine, 1998

    Formation

    • Stage en physiologie foetale, University of California at San Francisco, 1995
    • Stage en échocardiographie, Hospital for Sick Children, Toronto (foetale, transesophagique et transthoracique), 1994
    • Certification en pédiatrie (1992) et cardiologie (1993), Collège royal des médecins et chirurgiens du Canada, Collège des médecins du Québec

    Intérêts de recherche

    • Évaluation échocardiographique de la physiologie cardiovasculaire foetale et pédiatrique
    • Étiologies génétiques des cardiopathies congénitales

    Prix et distinctions

    • Prix Richard D. Rowe en cardiologie périnatale

Publications

Carotid wall elastography to assess midterm vascular dysfunction secondary to intrauterine growth restriction: Feasibility and comparison with standardized intima-media thickness - Maurice R, Vaujois L, Dahdah NS, Chibab N, Maurice A, Nuyt A-M, Levy E, Bigras JL. Carotid wall elastography to assess midterm vascular dysfunction secondary to intrauterine growth restriction: Feasibility and comparison with standardized intima-media thickness. Ultrasound Med Biol 2014; (sous presse).

Innovation through wearable sensors to collect real-life data among pediatric patients with cardiometabolic risk ractors - Kestens Y, Barnett T, Mathieu ME, Henderson M, Bigras JL, Benoît T, St-Onge M, Lambert M. Innovation through wearable sensors to collect real-life data among pediatric patients with cardiometabolic risk ractors. Int J Pediatrics 2014; 2014: 328076.

Risk of congenital heart defects is influenced by genetic variation in folate metabolism - Christensen KE, Zada YF, Rohlicek C, Andelfinger G, Michaud JL, Bigras JL, Richter A, Dubé MP, Rozen R. Risk of congenital heart defects is influenced by genetic variation in folate metabolism. Cardiol Young 2013; 23(1): 89–98.

Assessment of uterine artery and aortic isthmus Doppler recordings as predictors of necrotizing enterocolitis - Raboisson MJ, Huissoud C, Lapointe A, Hugues N, Bigras JL, Brassard M, Lamoureux J, Fouron J-C. Assessment of uterine artery and aortic isthmus Doppler recordings as predictors of necrotizing enterocolitis. Am J Obstet Gynecol 2012; 206(3): 232.e1-6.

Multidisciplinary management of a hepatic and renal transplant patient with Alagille syndrome - Maisonneuve E, Morin F, Crochetière C, Lemyre E, Bigras JL, Leduc L, Girardin C, Bilodeau M. Multidisciplinary management of a hepatic and renal transplant patient with Alagille syndrome. Int J Obstet Anesth 2012; 21(4): 382-383.

Right pulmonary artery torsion following surgical reimplantation - Martinez PD, Dery J, Vobecky S, Bigras JL, Lapierre C. Right pulmonary artery torsion following surgical reimplantation. Pediatr Radiol 2012; 42(12): 1514-1516.

Rare copy number variants contribute to congenital left-sided heart disease - Hitz MP, Lemieux-Perreault LP, Marshall C, Feroz-Zada Y, Davies R, Yang SW, Lionel AC, D'Amours G, Lemyre E, Cullum R, Bigras JL, Thibeault M, Chetaille P, Montpetit A, Khairy P, Overduin B, Klaassen R, Hoodless P, Awadalla P, Hussin J, Idaghdour Y, Nemer M, Stewart A, Boerkoel CF, Scherer SW, Richter A, Dubé MP, Andelfinger G. Rare copy number variants contribute to congenital left-sided heart disease. PLoS Genet 2012; 8(9): e1002903.

Design and rationale of a genetic cohort study on congenital cardiac disease: experiences from a multi-institutional platform in Quebec - Dubé MP, Bigras JL, Thibeault M, Bureau N, Chetaille P, Richter A, Mercier J, Bellavance M, Rohlicek C, Rozen R, Nemer M, Khairy P, Gendron R, Andelfinger G. Design and rationale of a genetic cohort study on congenital cardiac disease: experiences from a multi-institutional platform in Quebec. Cardiol Young 2011; 21(6): 654-664.

Unilateral absence of pulmonary artery in children: bronchovascular anatomy, natural course and effect of treatment on lung growth - Alison M, Garel L, Bigras JL, Dery J, Lapierre C. Unilateral absence of pulmonary artery in children: bronchovascular anatomy, natural course and effect of treatment on lung growth. Pediatr Radiol 2011; 41(4): 459-468.

Therapeutic strategies in children with an isolated unilaterally absent proximal pulmonary artery - Krammoh EK, Bigras JL, Prsa M, Lapierre C, Miró J, Dahdah NS. Therapeutic strategies in children with an isolated unilaterally absent proximal pulmonary artery. Pediatr Cardiol 2010; 31(5): 607-610.

Cardiac arrhythmias associated with severe traumatic brain injury and hypothermia therapy - Bourdages M, Bigras JL, Farrell CA, Hutchison JS, Lacroix J, Canadian Critical Care Trials Group. Cardiac arrhythmias associated with severe traumatic brain injury and hypothermia therapy. Pediatr Crit Care Med 2010; 11(3): 408-414.

Partial anomalous pulmonary venous return to the azygos vein: an unusual case - Lapierre C, Siles A, Bigras JL. Partial anomalous pulmonary venous return to the azygos vein: an unusual case. Pediatr Cardiol 2010; 31(5): 749-750.

Infected pacemaker causing septic lung emboli detected on FDG PET/CT - Abikhzer G, Turpin S, Bigras JL. Infected pacemaker causing septic lung emboli detected on FDG PET/CT. J Nucl Cardiol 2010; 17(3): 514-515.

Feasibility and reliability of Doppler flow recordings in the fetal aortic isthmus: a multicenter evaluation - Fouron J-C, Siles A, Montanari L, Morin L, Ville Y, Mivelaz Y, Proulx F, Bureau N, Bigras JL, Brassard M. Feasibility and reliability of Doppler flow recordings in the fetal aortic isthmus: a multicenter evaluation. Ultrasound Obstet Gynecol 2009; 33(6): 690-693.

The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects - Christensen KE, Rohlicek C, Andelfinger G, Michaud JL, Bigras JL, Richter A, Mackenzie AM, Rozen R. The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects. Hum Mutat 2009; 30(2): 212-220.

Cardiovascular evaluation of fetal anemia due to alloimmunization - Bigras JL, Suda K, Dahdah NS, Fouron J-C. Cardiovascular evaluation of fetal anemia due to alloimmunization. Fetal Diagn Ther 2008; 24(3): 197-202.

Differential pulmonary perfusion scan after percutaneous occlusion of the patent ductus arteriosus: one-decade consecutive longitudinal study from a single institution - Kramoh EK, Miró J, Bigras JL, Turpin S, Lambert R, Lapierre C, Jin W, Dahdah NS. Differential pulmonary perfusion scan after percutaneous occlusion of the patent ductus arteriosus: one-decade consecutive longitudinal study from a single institution. Pediatr Cardiol 2008; 29(5): 918-922.

Arythmies cardiaques - Bigras JL, Chantepie A, Côté JM, Fournier A. Arythmies cardiaques. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 175-185.

Cardiopathies congénitales - Bigras JL, Fournier A, Vobecky S, Fouron J-C, Michaud JL. Cardiopathies congénitales. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 231-244.

Endocardite bactérienne - Bigras JL, Carceller A, Lamarre V, Joyal JS. Endocardite bactérienne. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 499-505.

Insuffisance cardiaque - Bigras JL, Fournier A. Insuffisance cardiaque. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 736-739.

Sport et exercise - Martin E, Bigras JL, Rousseau E. Sport et exercise. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 67-79.

Surveillance cardiorespiratoire - Roze JC, Bigras JL. Surveillance cardiorespiratoire. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 3-33.

Palivizumab use among children with congenital heart disease in Québec: impact of Canadian guidelines on clinical practice - Bellavance M, Rohlicek C, Bigras JL, Côté JM, Paquet M, Lebel MH, Mackie AS. Palivizumab use among children with congenital heart disease in Québec: impact of Canadian guidelines on clinical practice. Pediatr Child Health 2006; 11(1): 19-23.

Predicting outcome in primary fetal hydrothorax - Klam S, Bigras JL, Hudon L. Predicting outcome in primary fetal hydrothorax. Fetal Diagn Ther 2005; 20(5): 366-370.

Prenatal cardiovascular manifestations in twin-to-twin transfusion Syndrome (TTTS) and the impact of therapeutic amnioreduction - Barrea C, Alkazaleh F, Ryan G, McCrindle BW, Roberts A, Bigras JL, Barrett J, Seaward PGR, Smallhorn J, Hornberger LK. Prenatal cardiovascular manifestations in twin-to-twin transfusion Syndrome (TTTS) and the impact of therapeutic amnioreduction. Am J Obstet Gynecol 2005; 192(3): 892-902.

Best cases from the AFIP - Cardiac metastases from melanoma - Tesolin H, Lapierre C, Oligny LL, Bigras JL, Champagne M. Best cases from the AFIP - Cardiac metastases from melanoma. Radiographics 2005; 25(1): 249-253.

Echocardiographic evaluation of fetal hydrothorax: the effusion ratio as a diagnostic tool - Bigras JL, Ryan G, Suda K, Silva A, Seaward PGR, Windrim R, McCrindle BW. Echocardiographic evaluation of fetal hydrothorax: the effusion ratio as a diagnostic tool. Ultrasound Obstet Gynecol 2003; 21(1): 37-40.

Management of fetal tachyarrhythmia based on superior vena cava/aorta Dopplier flow recordings - Fouron J-C, Fournier A, Proulx F, Lamarche J, Bigras JL, Boutin C, Brassard M, Gamache S. Management of fetal tachyarrhythmia based on superior vena cava/aorta Dopplier flow recordings. Heart 2003; 89(10): 1211-1216.

Acquired right ventricular outflow tract obstruction in the recipient twin in twin-twin transfusion syndrome - Lougheed J, Sinclair B, Fun Kee Fung K, Bigras JL, Ryan G, Smallhorn J, Hornberger LK. Acquired right ventricular outflow tract obstruction in the recipient twin in twin-twin transfusion syndrome. J Am Coll Cardiol 2001; 38(5): 1533-1538.

Echocardiographic predictors of outcome in newborns with congenital diaphragmatic hernia - Suda K, Bigras JL, Bohn D, Hornberger LK, McCrindle BW. Echocardiographic predictors of outcome in newborns with congenital diaphragmatic hernia. Pediatr Res 2000; 105(5): 1106-1109.

Superiority of three-dimensional versus two-dimensional echocardiography for left ventricular volume assessment in small piglet hearts - Abdullah M, Maeno Y, Bigras JL, McCrindle BW, Smallhorn J, Boutin C. Superiority of three-dimensional versus two-dimensional echocardiography for left ventricular volume assessment in small piglet hearts. J Am Soc Echocardiogr 2000; 13(10): 918-923.

Gene transfer in utero biologically engineers a patent ductus in lambs by arresting fibronectin-dependent neointimal formation - Mason CAE, Bigras JL, O'Blenes S, Zhou B, Rabinovitch M. Gene transfer in utero biologically engineers a patent ductus in lambs by arresting fibronectin-dependent neointimal formation. Nat Med 1999; 5(2): 176-182.

Dilated cardiomyopathy as a first sign nutritional vitamin D deficiency rickets in infancy - Abdullah M, Bigras JL, McCrindle BW. Dilated cardiomyopathy as a first sign nutritional vitamin D deficiency rickets in infancy. Can J Cardiol 1999; 26: 699-701.

Factors affecting the prognosis of Ebstein's anomaly during fetal life - Pavlova M, Fouron J-C, Drblik SP, van Doesburg NH, Bigras JL, Smallhorn J, Harder J, Robertson M. Factors affecting the prognosis of Ebstein's anomaly during fetal life. Am Heart J 1998; 135: 1081-1085.

Cardiovascular responses to dynamic submaximal exercise in children treated with anthracycline - Johnson D, Perrault H, Fournier A, Leclerc JM, Bigras JL, Davignon A. Cardiovascular responses to dynamic submaximal exercise in children treated with anthracycline. Am Heart J 1997; 133(2): 169-173.

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Créée le 22 juillet 2014
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