Chercheur

    Philippe Jouvet , M.D. , Ph.D.

    philippe.jouvet@umontreal.ca
    Philippe Jouvet
    Axe de recherche
    Santé métabolique et maladies complexes
    Thème de recherche
    Santé respiratoire
    Adresse
    CHUSJ

    Téléphone
    514 345-4931 #4927

    Fax
    514 345-7731

    Titres

    • Professeur titulaire de clinique, Département de pédiatrie, CHU Sainte-Justine
    • Directeur adjoint, Interactions ventilation mécanique/patients au Québec, Réseau en santé respiratoire, Fonds de recherche du Québec – Santé  (FRQS) 

    Formation

    • MSc en management hospitalier, Université Paris VII, 2003
    • PhD en nutrition humaine, Université Paris VII, 2001
    • MS en nutrition humaine, Université Paris VII, 1992
    • Spécialisation en soins intensifs, Université Paris VII, 1990
    • Spécialisation en pédiatrie, Université Paris VII, 1989
    • MD, Université Paris V, 1989

    Intérêts de recherche

    • Recherche clinique appliquée concernant l’assistance respiratoire, la nutrition et l’épuration extra-rénale aux soins intensifs pédiatriques
    • Informatisation de l’aide diagnostique et thérapeutique aux soins intensifs

    Prix et distinctions

    • Chercheur-boursier Junior 2 Fonds de recherche du Québec en santé, 2011-2015
    • Chercheur-boursier Junior 1, Fonds de la recherche en santé du Québec, 2007-2011

Publications

Molecular Absorbent Recirculating System therapy (MARS®) in pediatric acute liver failure: a single center experience - Bourgoin P, Mérouani A, Phan V, Litalien C, Lallier M, Alvarez F, Jouvet P. Molecular Absorbent Recirculating System therapy (MARS®) in pediatric acute liver failure: a single center experience. Pediatr Nephrol 2014; 29(5): 901-908.

Weaning children from mechanical ventilation with a computer-driven protocol: a pilot trial - Jouvet P, Payen V, Gauvin F, Emeriaud G, Lacroix J. Weaning children from mechanical ventilation with a computer-driven protocol: a pilot trial. Intensive Care Med 2013; 39(5): 919-925.

Simulations for mechanical ventilation in children: review and future prospects - Flechelles O, Ho A, Hernert P, Emeriaud G, Zaglam N, Cheriet F, Jouvet P. Simulations for mechanical ventilation in children: review and future prospects. Crit Care Res Pract 2013; 2013: 943281


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Innate immune function and mortality in critically ill children with influenza: a multicenter study - Hall M, Geyer SM, Guo CY, Panoskaltsis-Mortari A, Jouvet P, Ferdinands J, Shay DK, Nateri J, Greathouse K, Sullivan R, Tran T, Keisling S, Randolph AG, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network PICFlu Study Investigators. Innate immune function and mortality in critically ill children with influenza: a multicenter study. Crit Care Med 2013; 41(1): 224-236.

Threshold for toxicity from hyperammonemia in critically ill children - Ozanne B, Nelson J, Cousineau J, Lambert MA, Phan V, Mitchell GA, Alvarez F, Ducruet T, Jouvet P. Threshold for toxicity from hyperammonemia in critically ill children. J Hepatol 2012; 56(1): 123-128.

A pilot prospective study on closed loop controlled ventilation and oxygenation in ventilated children during the weaning phase - Jouvet P, Eddington A, Payen V, Bordessoule A, Emeriaud G, Gasco RL, Wysocki M. A pilot prospective study on closed loop controlled ventilation and oxygenation in ventilated children during the weaning phase. Crit Care 2012; 16(3): R85 doi:10.1186/cc11343


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Organization and management of mechanical ventilation worldwide - Jouvet P, Ben Jaballah N, Hamlaoui M, Newth C, Farias J, Monteverde E, Poterala R, von Dessauer B, Leclerc F, Erickson S. Organization and management of mechanical ventilation worldwide. Dans: Rimensberger P (ed). Pediatric and Neonatal Mechanical Ventilation: from Basics to Clinical Practice. Springer Verlag, 2012; (sous presse).

Explicit computerized protocols for mechanical ventilation in children and neonates - Jouvet P, Newth C. Explicit computerized protocols for mechanical ventilation in children and neonates. Dans: Rimensberger P (ed). Pediatric and Neonatal Mechanical Ventilation: from Basics to Clinical Practice. Springer Verlag, 2012; (sous presse).

Automation of weaning in children - Jouvet P, Mersmann S, Wysocki M. Automation of weaning in children. Dans: Rimensberger P (ed). Pediatric and Neonatal Mechanical Ventilation: from Basics to Clinical Practice. Springer Verlag, 2012; (sous presse).

Dialytic management of inborn errors of metabolism - Jouvet P, Schaefer F. Dialytic management of inborn errors of metabolism . Dans: Warady B, Schaefer F, Alexander S (ed). Pediatric Dialysis, 2nd edition. Springer Verlag, 2012; 765-774.

Insuffisance rénale aiguë et techniques d’épuration extra-rénale en réanimation pédiatrique - Aizenfisz S, Macher MA, Jouvet P. Insuffisance rénale aiguë et techniques d’épuration extra-rénale en réanimation pédiatrique. Dans: Paul O, Orliaguet G (eds). Le point sur la réanimation chirurgicale pédiatrique. Paris. Springer Verlag, 2012; (sous presse).

2009 H1N1 pandemic: still questions to answer!* - Flechelles O, Jouvet P. 2009 H1N1 pandemic: still questions to answer!*. Pediatr Crit Care Med 2012; 13(6): 690-691.

You must walk before you can run - Wilson D, Thomas N, Jouvet P. You must walk before you can run. Pediatr Crit Care Med 2012; 13(6): 691-692.

Risk factors associated with increased length of mechanical ventilation in children - Payen V, Jouvet P, Lacroix J, Ducruet T, Gauvin F. Risk factors associated with increased length of mechanical ventilation in children. Pediatr Crit Care Med 2012; 13(2): 152-157.

Acute kidney injury in children - Mérouani A, Flechelles O, Jouvet P. Acute kidney injury in children. Minerva Pediatr 2012; 64(2): 121-133.

Spinal cord injury and hemorrhage after chest compressions: A case report - Samson ME, Willems C, Lapierre P, Jouvet P. Spinal cord injury and hemorrhage after chest compressions: A case report. J Pediatric Neuroradiol 2012; 1(1): 55-58.

Neurally adjusted ventilatory assist improves patient–ventilator interaction in infants as compared with conventional ventilation - Bordessoule A, Emeriaud G, Morneau S, Jouvet P, Beck J. Neurally adjusted ventilatory assist improves patient–ventilator interaction in infants as compared with conventional ventilation. Pediatr Res 2012; 72(2): 194-202.

Development and implementation of explicit computerized protocols for mechanical ventilation in children - Jouvet P, Hernert P, Wysocki M. Development and implementation of explicit computerized protocols for mechanical ventilation in children. Ann Intensive Care 2011; 1(1): 51. doi: 10.1186/2110-5820-1-51.

Impact of blood volume monitoring on fluid removal during intermittent hemodialysis of critically ill children with acute kidney injury - Merouani A, Kechaou W, Litalien C, Ducruet T, Jouvet P. Impact of blood volume monitoring on fluid removal during intermittent hemodialysis of critically ill children with acute kidney injury. Nephrol Dial Transpl 2011; 26(10): 3315-3319.

Pandemic H1N1 influenza - Kumar A, Jouvet P, Christian M, Fowler R. Pandemic H1N1 influenza. Dans: Gilchrist IC, Cheng EY (eds). Current Concepts in Adult Critical Care. Des Plaines. Society of Critical Care Medicine, 2011; 71-78.

Critical pertussis: an exemple of pediatric disease that necessitates a large collaborative network - Emeriaud G, Jouvet P. Critical pertussis: an exemple of pediatric disease that necessitates a large collaborative network. Pediatr Crit Care Med 2011; 12(4): 467-468.

Hyperammonemia and neonatal cardiac failure - Adamovic T, Jouvet P, Vobecky S, Garel L, Rougemont A-L, Alvarez F. Hyperammonemia and neonatal cardiac failure. Minerva Anestesiol 2011; 77(5): 554-557.

Potential pediatric intensive care unit demand/capacity mismatch due to novel pH1N1 in Canada - Stiff D, Kumar A, Kissoon N, Fowler R, Jouvet P, Skippen P, Smetanin P, Kesselman M, Veroukis S. Potential pediatric intensive care unit demand/capacity mismatch due to novel pH1N1 in Canada. Pediatr Crit Care Med 2011; 12(2): e51-57.

The care of critically ill children after hematopoietic SCT: a North American survey - McArthur J, Pettersen G, Jouvet P, Christensen M, Tamburro R. The care of critically ill children after hematopoietic SCT: a North American survey. Bone Marrow Transplant 2011; 46(2): 227-231.

Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children - Rose L, Schultz MJ, Cardwell CR, Jouvet P, McAuley D. Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children. Cochrane DB Syst Rev 2011; 15(6): R295. doi: 10.1186/cc10588.

Paediatric mortality related to H1N1 infection in England - Fowler R, Jouvet P. Paediatric mortality related to H1N1 infection in England. Lancet 2010; 376(9755): 1808-1810.

Improving interhospital paediatric transport - Jouvet P, Lacroix J. Improving interhospital paediatric transport. Lancet 2010; 376(9742): 660-661.

Critical illness in children with influenza A/pH1N1 2009 infection in Canada - Jouvet P, Hutchison J, Pinto R, Menon K, Rodin R, Choong K, Kesselman M, Veroukis S, André Dugas M, Santschi M, Guerguerian A-M, Withington D, Alsaati B, Joffe A, Drews T, Skippen P, Rolland E, Kumar A, Fowler R, Canadian Critical Care Trials Group. Critical illness in children with influenza A/pH1N1 2009 infection in Canada. Pediatr Crit Care Med 2010; 11(5): 603-609
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Épuration extra-corporelle continue en réanimation pédiatrique - Jouvet P. Épuration extra-corporelle continue en réanimation pédiatrique. Dans: Labrune P, Oriot D, Labrune B, Huault G. Urgences pédiatriques. Paris. Estem S.A., 2010; 1576-1579.

Dialyse péritonéale (et lavage péritonéal diagnostic) - Jouvet P. Dialyse péritonéale (et lavage péritonéal diagnostic). Dans: Labrune P, Oriot D, Labrune B, Huault G. Urgences pédiatriques. Paris. Estem S.A., 2010; 1571-1575.

Échanges plasmatiques - Jouvet P. Échanges plasmatiques. Dans: Labrune P, Oriot D, Labrune B, Huault G. Urgences pédiatriques. Paris. Estem S.A., 2010; 1580-1582.

Oedèmes pulmonaires - Bordessoule A, Jouvet P. Oedèmes pulmonaires. Dans: Labrune P, Oriot D, Labrune B, Huault G. Urgences pédiatriques. Paris. Estem S.A., 2010; 83-85.

Draining fluids through a peritoneal catheter in newborns after cardiac surgery helps to control fluid balance - Ruano Cea E, Jouvet P, Vobecky S, Mérouani A. Draining fluids through a peritoneal catheter in newborns after cardiac surgery helps to control fluid balance. Case Report Med 2010; 2010: 731865.

Recording diaphragm activity by an oesophageal probe: a new tool to evaluate the recovery of diaphragmatic paralysis - Bordessoule A, Emeriaud G, Delnard N, Beck J, Jouvet P. Recording diaphragm activity by an oesophageal probe: a new tool to evaluate the recovery of diaphragmatic paralysis. Intensive Care Med 2010; 36(11) : 1978-1979.

Acute lung injury in children: Therapeutic practice and feasibility of international clinical trials - Santschi M, Jouvet P, Leclerc F, Gauvin F, Newth CJ, Carroll CL, Flori H, Tasker R, Rimensberger P, Randolph AG, for the PALIVE Investigators, the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI), the European Society of Pediatric and Neonatal Intensive Care (ESPNIC). Acute lung injury in children: Therapeutic practice and feasibility of international clinical trials. Pediatr Crit Care Med 2010; 11(6): 681-689.

Early observational research and registries during the 2009 influenza A pandemic - Fowler R, Webb SA, Rowan KM, Sprung CL, Thompson BT, Randolph AG, Jouvet P, Lapinsky S, Rubinson L, Rello J, Cobb JP, Rice TW, Uyeki T, Marshall J. Early observational research and registries during the 2009 influenza A pandemic. Crit Care Med 2010; 38(4 suppl): e120-132.

Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada - Freed DH, Henzler D, White CW, Fowler R, Zarychanski R, Hutchison J, Arora RC, Manji RA, Legare JF, Drews T, Veroukis S, Kesselman M, Guerguerian A-M, Kumar A, Jouvet P, Canadian Critical Care Trials Group. Extracorporeal lung support for patients who had severe respiratory failure secondary to influenza A (H1N1) 2009 infection in Canada. Can J Anaesth 2010; 57(3): 240-247.

Towards in vivo microimaging of lung inflammation and repair: current issues and future direction - Lesur O, Charette PG, Jouvet P, Cheriet F, Chagnon F. Towards in vivo microimaging of lung inflammation and repair: current issues and future direction. Dans: Méndez-Vilas A, Diaz J (eds). Microscopy: Science, Technology, Applications and Education. Badajoz (Espagne). Formatex, 2010; 633-640.

Les défis de l'assistance respiratoire chez l'enfant (nouveau-nés exclus) - Jouvet P, Payen V, Bordessoule A, Fontana M. Les défis de l'assistance respiratoire chez l'enfant (nouveau-nés exclus). Rev Mal Respir 2009; 1: 136-138.

Assessment of calorie prescribed and delivered in critically ill children: pilot study - Bockenkamp B, Jouvet P, Arsenault V, Beauséjour M, Pelletier V. Assessment of calorie prescribed and delivered in critically ill children: pilot study. e-SPEN 2009; 35: 1140-1141.

Humidification performances of 48 passive airway humidifiers: Comparison with manufacturers' data - Lellouche F, Taillé S, Lefrançois F, Deye N, Maggiore SM, Jouvet P, Ricard JD, Fumagali B, Brochard L, and "Groupe de travail sur les respirateurs de l'AP-HP". Humidification performances of 48 passive airway humidifiers: Comparison with manufacturers' data. Chest 2009; 135(2): 276-286.

Comment on "Adult ICU ventilators to provide neonatal ventilation: a lung simulator study" - Fontaine MM, Payot A, Morneau S, Jouvet P. Comment on "Adult ICU ventilators to provide neonatal ventilation: a lung simulator study". Intensive Care Med 2009; 35(6): 1140-1; author reply 1142.

Critically ill patients with novel swine origin influenza virus A/H1N1 infection in Canada - Kumar A, Zarychanski R, Pinto R, Cook D, Marshall J, Lacroix J, Stelfox T, Bagshaw S, Choong K, Lamontagne F, Turgeon A, Lapinsky S, Ahern SP, Smith O, Siddiqui F, Jouvet P, Khwaja K, McIntyre L, Menon K, Hutchison J, Hornstein D, Joffe A, Lauzier F, Singh J, Karachi T, Wiebe K, Olafson K, Ramsey C, Sharma S, Dodek P, Meade M, Hall R, Fowler R, for the Canadian Critical Care Trials Group H1N1 Collaborative. Critically ill patients with novel swine origin influenza virus A/H1N1 infection in Canada. JAMA 2009; 302(17): 1872-1879.

Metabolic encephalopathies in children - Jouvet P, Lortie A, Maranda B, Tasker R. Metabolic encephalopathies in children. Dans: Nichols DG (eds). Rogers Textbook of Pediatric Intensive Care. Philadelphia. Wolters Kluwer/Lippincott Williams & Wilkins, 2008; 973-983.

Bedside adherence to clinical practice guidelines in the intensive care unit: the TECLA study - Quenot JP, Mentec H, Feihl F, Annane D, Melot C, Vignon P, Brun-Buisson C, Jouvet P, TECLA Study Group. Bedside adherence to clinical practice guidelines in the intensive care unit: the TECLA study. Intensive Care Med 2008; 34(8): 1393-1400.

Renal replacement therapies in ICU - Butt W, Skipper P, Jouvet P, McBryde K. Renal replacement therapies in ICU. Dans: Nichols DG (eds). Rogers Textbook of Pediatric Intensive Care. Philadelphia. Wolters Kluwer/Lippincott Williams & Wilkins, 2008; 564-583.

Insuffisance hépatique aiguë - Jouvet P, Alvarez F. Insuffisance hépatique aiguë. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 739-744.

Acute lung injury: is volume the question? - Jouvet P, Lacroix J. Acute lung injury: is volume the question?. Pediatr Crit Care Med 2007; 8(4): 397-398.

Weaning children from mechanical ventilation with a computer-driven system (closed-loop protocol): A pilot study - Jouvet P, Farges C, Hatzakis G, Lesage F, Dupic L, Brochard L, Hubert P. Weaning children from mechanical ventilation with a computer-driven system (closed-loop protocol): A pilot study. Pediatr Crit Care Med 2007; 8(5): 425-432.

Assistance respiratoire - Jouvet P, Leclerc F, Rimensberger P, Morneau S, Hatzakis G, Tucci M, Robert D, Bougatef A, Lacroix J. Assistance respiratoire. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 35-61.

Décompensation aiguë de maladies héréditaires du métabolisme - Jouvet P, Saudubray JM, de Pascau L, Mitchell GA, Lambert MA. Décompensation aiguë de maladies héréditaires du métabolisme. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 843-863.

Impact of inborn errors of metabolism on admission and mortality in a pediatric intensive care unit - Jouvet P, Touati G, Lesage F, Dupic L, Tucci M, Saudubray JM, Hubert P. Impact of inborn errors of metabolism on admission and mortality in a pediatric intensive care unit. Eur J Pediatr 2007; 166(5): 461-465.

Acceptable respiratory physiological limits for children during the weaning phase of mechanical ventilation - Santschi M, Gauvin F, Hatzakis G, Lacroix J, Jouvet P. Acceptable respiratory physiological limits for children during the weaning phase of mechanical ventilation. Intensive Care Med 2007; 33(2): 319-325.

Thérapies vasculaires d'épuration extrarénale continue - Litalien C, Mérouani A, Phan V, Gouyon J-B, Jouvet P. Thérapies vasculaires d'épuration extrarénale continue. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 1229-1252.

Maladies métaboliques à expression néonatales - Mitchell GA, Lambert MA, Jouvet P, Payot A. Maladies métaboliques à expression néonatales. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 833-838.

A nutritional support team in the pediatric intensive care unit: Changes and factors impeding appropriate nutrition - Lambe C, Hubert P, Jouvet P, Cosnes J, Colomb V. A nutritional support team in the pediatric intensive care unit: Changes and factors impeding appropriate nutrition. Clin Nutr 2007; 26(3): 355-363.

Ventilation non invasive en réanimation pédiatrique: indications, modalités [Non invasive ventilation in children] - Jouvet P, Morneau S, Payen V, Santschi M. Ventilation non invasive en réanimation pédiatrique: indications, modalités [Non invasive ventilation in children]. Arch Pediatr 2006; 13(6): 804-806.

Épuration extrarénale chez l'enfant - Jouvet P, Litalien C, Phan V, Mérouani A. Épuration extrarénale chez l'enfant. Dans: Bastien O, Honoré P, Robert R (eds). Circulations extra-corporelles en réanimation. Paris. Elsevier, 2006; 193-210.

Validation of a sedation scale for young mechanically ventilated children: a painful challenge? - Litalien C, Jouvet P. Validation of a sedation scale for young mechanically ventilated children: a painful challenge?. Pediatr Crit Care Med 2006; 7(2): 183-184.

Methylmalonic and propionic acidurias: Management without or with a few supplements of specific amino acid mixture - Touati G, Valayannopoulos V, Mention K, de Lonlay P, Jouvet P, Depondt E, Assoun M, Souberbielle JC, Rabier D, Ogier de Baulay H, Saudubray JM. Methylmalonic and propionic acidurias: Management without or with a few supplements of specific amino acid mixture. J Inherit Metab Dis 2006; 29(2-3): 288-298.

Duration of extracorporeal therapy in acute maple syrup urine disease: a kinetic model - Phan V, Clermont MJ, Mérouani A, Litalien C, Tucci M, Lambert MA, Mitchell GA, Jouvet P. Duration of extracorporeal therapy in acute maple syrup urine disease: a kinetic model. Pediatr Nephrol 2006; 21(5): 698-704.

Pathophysiology of impaired ovarian function in galactosaemia - Forges T, Monnier-Barbarino P, Leheup B, Jouvet P. Pathophysiology of impaired ovarian function in galactosaemia. Hum Reprod Update 2006; 12(5): 573-584.

Kinetic modeling of plasma leucine levels during continuous venovenous extracorporeal removal therapy in neonates with maple syrup urine disease - Jouvet P, Hubert P, Saudubray JM, Rabier D, Man NK. Kinetic modeling of plasma leucine levels during continuous venovenous extracorporeal removal therapy in neonates with maple syrup urine disease. Pediatr Res 2005; 58(2): 278-282.

Oedèmes pulmonaires - Jouvet P, De Blic J. Oedèmes pulmonaires. Dans: Labrune P, Oriot D, Labrune B, Huault G. Urgences pédiatriques. Pathologies: clinique, examens, stratégies, gestes. Paris. Estem, 2004; 83-85.

Échanges plasmatiques - Jouvet P. Échanges plasmatiques. Dans: Labrune P, Oriot D, Labrune B, Huault G. Urgences pédiatriques. Pathologies: clinique, examens, stratégies, gestes. Paris. Estem, 2004; 1580-1582.

Épuration extracorporelle continue - Jouvet P. Épuration extracorporelle continue. Dans: Labrune P, Oriot D, Labrune B, Huault G. Urgences pédiatriques. Pathologies: clinique, examens, stratégies, gestes. Paris. Estem, 2004; 1576-1579.

Prise en charge des maladies héréditaires du métabolisme par intoxication endogène en réanimation pédiatrique - Jouvet P. Prise en charge des maladies héréditaires du métabolisme par intoxication endogène en réanimation pédiatrique. Dans: Société de réanimation de langue française. Actualités en Réanimation et Urgences 2004. Paris. Elsevier, 2004; 547-556.

Fetal home monitoring for the prenatal management of gastroschisis - Salomon LJ, Mahieu-Caputo D, Jouvet P, Jouannic JM, Benachi A, Grebille AG, Dumez Y, Dommergues M. Fetal home monitoring for the prenatal management of gastroschisis. Acta Obstet Gynecol Scand 2004; 83: 1061-1064.

Dialyse péritonéale et lavage péritonéal - Jouvet P. Dialyse péritonéale et lavage péritonéal. Dans: Labrune P, Oriot D, Labrune B, Huault G. Urgences pédiatriques. Pathologies: clinique, examens, stratégies, gestes. Paris. Estem, 2004; 1571-1575.

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