Chercheur

    Guy Van Vliet , M.D.

    guy.van-vliet@recherche-ste-justine.qc.ca
    Guy Van Vliet
    Axe de recherche
    Pathologies fœtomaternelles et néonatales
    Thème de recherche
    Étude des mécanismes des malformations congénitales
    Adresse
    CHUSJ

    Téléphone
    514 345-4931 #4735

    Fax
    514 345-4988

    Sommaire de carrière

    Guy Van Vliet a complété ses études médicales en 1976 à l'Université Libre de Bruxelles où il a ensuite fait sa résidence en pédiatrie de 1976 à 1980. Il a poursuivi ses études postdoctorales en endocrinologie pédiatrique à l'Université de la Californie, San Francisco de 1980 à 1983 avant de retourner à Bruxelles à titre de pédiatre-endocrinologue. Depuis 1989, il oeuvre au CHU Sainte-Justine à titre de chef du Service d'endocrinologie depuis 1991. Il est également professeur titulaire au Département de pédiatrie à l'Université de Montréal depuis 1995.

    Les intérêts de recherche du Dr Van Vliet portent principalement sur la pathophysiologie moléculaire et le dépistage de l’hypothyroïdie congénitale et sur la prise en charge et le devenir des enfants qui en sont atteints. Par ailleurs, Dr Van Vliet a établi un vaste réseau de collaborations afin d'étudier la base moléculaire de nombreuses maladies hypophysaires, thyroïdiennes, surrénaliennes et gonadiques chez l'enfant et l'adolescent.
     

Publications

Autonomous adenomas caused by somatic mutations of the thyroid-stimulating hormone receptor in children - Grob F, Deladoëy J, Legault L, Spigelblatt L, Fournier A, Vassart G, Van Vliet G. Autonomous adenomas caused by somatic mutations of the thyroid-stimulating hormone receptor in children. Horm Res Ped 2014; 81(2): 73-79.

Role for tissue-dependent methylation differences in the expression of FOXE1 in non-tumoral thyroid glands - Abu-Khudir R, Magne F, Chanoine JP, Deal C, Van Vliet G, Deladoëy J. Role for tissue-dependent methylation differences in the expression of FOXE1 in non-tumoral thyroid glands. J Clin Endocrinol Metab 2014; (sous presse).

Hypothyroidism in infants and children: neonatal screening - Van Vliet G, Deladoëy J. Hypothyroidism in infants and children: neonatal screening. Dans: Braverman LE, Cooper D (eds). The Thyroid: A Fundamental and Clinical Text, 10th edition. Philadelphia, PA. Lippincott, Williams & Wilkins, 2013; 787-802.

Whole exome sequencing: opportunities in pediatric endocrinology - Samuels ME, Hasselmann C, Deal C, Deladoëy J, Van Vliet G. Whole exome sequencing: opportunities in pediatric endocrinology. Personalized Med 2013; (sous presse).

Treating congenital hypothyroidism--which levothyroxine? - Deladoëy J, Van Vliet G. Treating congenital hypothyroidism--which levothyroxine?. Nat Rev Endocrinol 2013; 9(5) : 257-258.

Rising serum thyroxine levels and chorea in graves' disease - Leblicq C, Duval M, Carmant L, Van Vliet G, Alos N. Rising serum thyroxine levels and chorea in graves' disease. Pediatrics 2013; 131(2): e616-619.

Quality of referral of short children to the paediatric endocrinologist and impact of a fax communication system - Chiniara L, Perry RJ, Van Vliet G, Huot C, Deal C. Quality of referral of short children to the paediatric endocrinologist and impact of a fax communication system. Paediatr Child Health 2013; 18(10): 533-537.

Thyroid function from birth to adolescence in Prader-Willi syndrome - Sharkia M, Michaud S, Berthier MT, Giguere Y, Stewart L, Deladoëy J, Deal C, Van Vliet G, Chanoine JP. Thyroid function from birth to adolescence in Prader-Willi syndrome. Hum Brain Mapp 2013; 163(3): 800-805.

Bioinactive ACTH causing glucocorticoid deficiency - Samuels ME, Gallo-Payet N, Pinard S, Hasselmann C, Magne F, Patry L, Chouinard L, Schwartzentruber JA, René P, Sawyer N, Bouvier M, Djemli A, Delvin EE, Huot C, Eugène D, Deal C, Van Vliet G, Majewski J, Deladoëy J, FORGE Canada Consortium. Bioinactive ACTH causing glucocorticoid deficiency. J Clin Endocrinol Metab 2013; 98(2): 736-742.

A search for variables predicting cortisol response to low-dose corticotropin stimulation following supraphysiological doses of glucocorticoids - Wildi-Runge S, Deladoëy J, Bélanger C, Deal C, Van Vliet G, Alos N, Huot C. A search for variables predicting cortisol response to low-dose corticotropin stimulation following supraphysiological doses of glucocorticoids. J Pediatr 2013; 163(2): 484-488.e1.

Leydig cell tumors in children: contrasting clinical, hormonal, anatomical, and molecular characteristics in boys and girls - Olivier P, Simoneau-Roy J, Francoeur D, Sartelet H, Parma J, Vassard G, Van Vliet G. Leydig cell tumors in children: contrasting clinical, hormonal, anatomical, and molecular characteristics in boys and girls. J Pediatr 2012; 161(6): 1147-1152.

A high prevalence of dual thyroid ectopy in congenital hypothyroidism: evidence for insufficient signaling gradients during embryonic thyroid migration or for the polyclonal nature of the thyroid gland? - Wildi-Runge S, Stoppa-Vaucher S, Lambert R, Turpin S, Van Vliet G, Deladoëy J. A high prevalence of dual thyroid ectopy in congenital hypothyroidism: evidence for insufficient signaling gradients during embryonic thyroid migration or for the polyclonal nature of the thyroid gland?. J Clin Endocrinol Metab 2012; 97(6): E978-981.

Muscle-bone characteristics in children with Prader-Willi syndrome - Edouard T, Deal C, Van Vliet G, Gaulin N, Moreau A, Rauch F, Alos N. Muscle-bone characteristics in children with Prader-Willi syndrome. J Clin Endocrinol Metab 2012; 97(2): E275-281.

Is the incidence of congenital hypothyroidism really increasing? A 20-year retrospective population-based study in Québec - Deladoëy J, Ruel J, Giguere Y, Van Vliet G. Is the incidence of congenital hypothyroidism really increasing? A 20-year retrospective population-based study in Québec. J Clin Endocrinol Metab 2011; 96(8): 2422-2429.

Discovery of a fetal goiter on prenatal ultrasound in women treated for Graves' disease: first, do no harm - Stoppa-Vaucher S, Van Vliet G, Deladoëy J. Discovery of a fetal goiter on prenatal ultrasound in women treated for Graves' disease: first, do no harm. Thyroid 2011; 21(8): 931; author reply 932-933.

Variation by ethnicity in the prevalence of congenital hypothyroidism due to thyroid dysgenesis - Stoppa-Vaucher S, Van Vliet G, Deladoëy J. Variation by ethnicity in the prevalence of congenital hypothyroidism due to thyroid dysgenesis. Thyroid 2011; 21(1): 13-18.

Are guidelines for glucocorticoid coverage in adrenal insufficiency currently followed? - Leblicq C, Rottembourg D, Deladoëy J, Van Vliet G, Deal C. Are guidelines for glucocorticoid coverage in adrenal insufficiency currently followed?. J Pediatr 2011; 158(3): 492-498.e1.

Severe cortisol deficiency associated with reversible growth hormone deficiency in two infants: what is the link? - McEachern RR, Drouin J, Metherell L, Huot C, Van Vliet G, Deal C. Severe cortisol deficiency associated with reversible growth hormone deficiency in two infants: what is the link?. J Clin Endocrinol Metab 2011; 96(9): 2670-2674.

Is ultrasonography useful in predicting thyroid cancer in children with thyroid nodules and apparently benign cytopathologic features? - Saavedra J, Deladoëy J, Saint-Vil D, Boivin Y, Alos N, Deal C, Van Vliet G, Huot C. Is ultrasonography useful in predicting thyroid cancer in children with thyroid nodules and apparently benign cytopathologic features?. Horm Res Ped 2011; 75(4): 269-275.

Thyroid disorders - Jemli A, Van Vliet G, Delvin EE. Thyroid disorders. Dans: Dietzen DJ, Bennett MJ, Edward CC (eds). Biochemical and Molecular Basis of Pediatric Diseases, 4th edition. AACC Press, 2010; 155-170.

Non-immune goiter and hypothyroidism in a 19-week fetus: a plea for conservative treatment - Stoppa-Vaucher S, Francoeur D, Grignon A, Alos N, Polhenz J, Hermanns P, Van Vliet G, Deladoëy J. Non-immune goiter and hypothyroidism in a 19-week fetus: a plea for conservative treatment. J Pediatr 2010; 156(6): 1026-1029.

Genetics and epigenetics of congenital hypothyroidism - Van Vliet G. Genetics and epigenetics of congenital hypothyroidism. Dans: Windisford FE (ed). Clinical Management of the Thyroid Disease. Elsevier, 2009; 113-121.

Monozygotic twins are generally discordant for congenital hypothyroidism from thyroid dysgenesis (letter to the editor) - Van Vliet G, Vassard G. Monozygotic twins are generally discordant for congenital hypothyroidism from thyroid dysgenesis (letter to the editor). Horm Res 2009; 72(5): 320.

Disorders of the thyroid gland - Polak M, Van Vliet G. Disorders of the thyroid gland. Dans: Sarafoglou K (ed). Inborn Errors of Metabolism. McGraw-Hill, 2009; 355-382.

Comparison of adolescents with Klinefelter syndrome according to the circumstances of diagnosis: amniocentesis vs clinical signs - Girardin C, Lemyre E, Alos N, Deal C, Huot C, Van Vliet G. Comparison of adolescents with Klinefelter syndrome according to the circumstances of diagnosis: amniocentesis vs clinical signs. Horm Res 2009; 72(2): 98-105.

Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene - Maquet E, Costagliola S, Parma J, Christophe-Hobertus C, Oligny LL, Fournet JC, Robitaille Y, Vuissoz JM, Payot A, Laberge S, Vassard G, Van Vliet G, Deladoëy J. Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene. J Clin Endocrinol Metab 2009; 94(1): 197-203.

Outcome after bariatric surgery in two adolescents with hypothalamic obesity following treatment of craniopharyngioma - Rottembourg D, O'Gorman C, Urbach S, Garneau P, Van Vliet G, Huot C. Outcome after bariatric surgery in two adolescents with hypothalamic obesity following treatment of craniopharyngioma. J Pediatr Endocr Met 2009; 22(9): 867-872.

Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism - Raivio T, Sidis Y, Plummer L, Chen H, Ma J, Mukherjee A, Jacobson-Dickman EE, Quinton R, Van Vliet G, Lavoie H, Hughes VA, Dwyer A, Hayes FJ, Xu S, Sparks S, Kaiser UB, Mohammadi M, Pitteloud N. Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab 2009; 94(11): 4380-4390.

Molecular studies of a patient with complete androgen insensitivity and a 47,XXY karyotype - Girardin C, Deal C, Lemyre E, Paquette J, Lumbroso R, Beitel LK, Trifiro MA, Van Vliet G. Molecular studies of a patient with complete androgen insensitivity and a 47,XXY karyotype. J Pediatr 2009; 155(3): 439-443.

Hartsfield holoprosencephaly-ectrodactyly syndrome in five male patients: further delineation and review - Vilain C, Mortier G, Van Vliet G, Dubourg C, Heinrichs C, de Silva D, Verloes A, Baumann C. Hartsfield holoprosencephaly-ectrodactyly syndrome in five male patients: further delineation and review. Am J Med Genet A 2009; 149A(7): 1476-1481.

Retrospective study of the potential benefits and adverse events during growth hormone treatment in children with Prader-Willi syndrome - Fillion M, Deal C, Van Vliet G. Retrospective study of the potential benefits and adverse events during growth hormone treatment in children with Prader-Willi syndrome. J Pediatr 2009; 154(2): 230-233.

Treating fetal thyroid and adrenal disorders through the mother - Van Vliet G, Polak M, Ritzen M. Treating fetal thyroid and adrenal disorders through the mother. Nat Clin Pract Endoc 2008; 4(12): 675-682.

Meeting report: measuring endocrine-sensitive endpoints within the first years of life - Arbuckle TE, Hauser R, Swan SH, Mao CS, Longnecker MP, Main KM, Whyatt RM, Mendola P, Legrand M, Rovet J, Till C, Wade M, Jarrell J, Matthews S, Van Vliet G, Bornehag CG, Mieusset R. Meeting report: measuring endocrine-sensitive endpoints within the first years of life. Environ Health Perspect 2008; 116(7): 948-951.

Variation in growth hormone immunoassays in clinical practice in Canada - Amed S, Delvin EE, Hamilton J, Van Vliet G, on behalf of the Canadian Pediatric Endocrine Group. Variation in growth hormone immunoassays in clinical practice in Canada. Horm Res 2008; 69(5): 290-294.

Pseudodominant inheritance of goitrous congenital hypothyroidism caused by TPO mutations: molecular and in silico studies - Deladoëy J, Pfarr N, Vuissoz JM, Parma J, Vassart G, Biesterfeld S, Polhenz J, Van Vliet G. Pseudodominant inheritance of goitrous congenital hypothyroidism caused by TPO mutations: molecular and in silico studies. J Clin Endocrinol Metab 2008; 93(2): 627-633.

Mutations in prokineticin 2 (PROK2) and PROK2 receptor (PROKR2) in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum - Cole L, Sidis Y, Zhang C, Quinton R, Plummer L, Pignatelli D, Hughes VA, Dwyer A, Raivio T, Hayes FJ, Seminara S, Huot C, Alos N, Speiser P, Takeshita A, Van Vliet G, Pearce S, Crowley W, Zhou Q-Y, Pitteloud N. Mutations in prokineticin 2 (PROK2) and PROK2 receptor (PROKR2) in human gonadotrophin-releasing hormone deficiency: molecular genetics and clinical spectrum. J Clin Endocrinol Metab 2008; 93(9): 3551-3559.

Impact of patient characteristics and clinical factors on the decision to initiate growth hormone treatment in Turner syndrome - Khatchadourian K, Huot C, Alos N, Van Vliet G, Deal C. Impact of patient characteristics and clinical factors on the decision to initiate growth hormone treatment in Turner syndrome. Horm Res 2008; 70(5): 300-308.

Intellectual outcome of children with severe congenital hypothyroidism: treating at 20 days of life is not early enough - Van Vliet G. Intellectual outcome of children with severe congenital hypothyroidism: treating at 20 days of life is not early enough. J Clin Endocrinol Metab 2007; electronic letter.

Congenital hypothyroidism: Look at the whole patient! Editorial comment on the paper by El Kholy et al. in this issue - Van Vliet G. Congenital hypothyroidism: Look at the whole patient! Editorial comment on the paper by El Kholy et al. in this issue. Horm Res 2007; 68(6): 276-277.

Outcomes in CAH: need for evidence-based estimates - Grosse SD, Van Vliet G. Outcomes in CAH: need for evidence-based estimates. Horm Res 2007; 68(4): 203.

How many deaths can be prevented by newborn screening for congenital adrenal hyperplasia? - Grosse SD, Van Vliet G. How many deaths can be prevented by newborn screening for congenital adrenal hyperplasia?. Horm Res 2007; 67(6): 284-291.

Insuffisance surrénale - Moussa A, Van Vliet G, Tucci M. Insuffisance surrénale. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 755-761.

Polymorphic length of FOXE1 alanine stretch: evidence for genetic susceptibility to thyroid dysgenesis - Carre A, Castanet M, Sura-Trueba S, Szinnai G, Van Vliet G, Trochet D, Amiel J, Léger J, Czernichow P, Scotet V, Polak M. Polymorphic length of FOXE1 alanine stretch: evidence for genetic susceptibility to thyroid dysgenesis. Hum Genet 2007; 122(5): 467-476.

Apparent manifesting heterozygosity in P450 oxidoreductase deficiency and its effect on coexisting 21-hydroxylase deficiency - Scott R, Gomes LG, Huang N, Van Vliet G, Miller WL. Apparent manifesting heterozygosity in P450 oxidoreductase deficiency and its effect on coexisting 21-hydroxylase deficiency. J Clin Endocrinol Metab 2007; 92(6): 2318-2322.

Coding sequence analysis of GNRHR and GPR54 in patients with congenital and adult-onset forms of hypogonadotropic hypogonadism. - Cerrato F, Shagoury J, Kralickova M, Dwyer A, Falardeau J, Ozata M, Van Vliet G, Bouloux P, Hall J, Hayes FJ, Pitteloud N, Martin KA, Welt C, Seminara S. Coding sequence analysis of GNRHR and GPR54 in patients with congenital and adult-onset forms of hypogonadotropic hypogonadism.. Eur J Endocrinol 2007; 155 (suppl 1): S3-S10.

Random variability in congenital hypothyroidism from thyroid dysgenesis over 16 years in Quebec - Deladoëy J, Bélanger N, Van Vliet G. Random variability in congenital hypothyroidism from thyroid dysgenesis over 16 years in Quebec. J Clin Endocrinol Metab 2007; 92(8): 3158-3161.

Possible non-mendelian mechanisms of thyroid dysgenesis - Deladoëy J, Vassart G, Van Vliet G. Possible non-mendelian mechanisms of thyroid dysgenesis. Endocr Dev 2007; 10: 29-42.

Hyperthyroïdie et hypothyroïdie du nouveau-né et de l'enfant - Carranza D, Van Vliet G, Polak M. Hyperthyroïdie et hypothyroïdie du nouveau-né et de l'enfant. Dans: Encyclopédie Médico-Chirurgicale. France. Elsevier, 2006; 1-11.

[Congenital hypothyroidism] - Carranza D, Van Vliet G, Polak M. [Congenital hypothyroidism]. Ann Endocrinol (Paris) 2006; 67(4): 295-302.

Congenital hypothyroidism: from paracelsus to molecular diagnosis - Djemli A, Van Vliet G, Delvin EE. Congenital hypothyroidism: from paracelsus to molecular diagnosis. Clin Biochem 2006; 39(5): 511-518.

Normal minipuberty of infancy in boys with Prader-Willi syndrome - Filion M, Deal C, Van Vliet G. Normal minipuberty of infancy in boys with Prader-Willi syndrome. J Pediatr 2006; 149(6): 874-876.

Genomic imprinting in Turner syndrome: effects on response to growth hormone and on risk of sensorinal hearing loss - Hamelin C, Anglin G, Quigley CA, Deal C, Van Vliet G, on behalf of the Canadian GH Advisory Committee. Genomic imprinting in Turner syndrome: effects on response to growth hormone and on risk of sensorinal hearing loss. J Clin Endocrinol Metab 2006; 91(8): 3002-3010.

Effects of early high-dose Levothyroxine treatment on auditory brain event-related potentials at school entry in children with congenital hypothyroidism - Marti S, Alvarez M, Simoneau-Roy J, Leroux S, Van Vliet G, Robaey P. Effects of early high-dose Levothyroxine treatment on auditory brain event-related potentials at school entry in children with congenital hypothyroidism. Horm Res 2006; 66(5): 240-248.

Longitudinal study of thyroid function in Down's syndrome in the first two decades - Van Vliet G. Longitudinal study of thyroid function in Down's syndrome in the first two decades. J Pediatr 2005; 147(5): 707-708.

Neonatal endocrinopathies: should we change the screening methods? - Van Vliet G. Neonatal endocrinopathies: should we change the screening methods?. Ital J Pediatr 2005; 31: 209-212.

Hypothyroidism in infants and children - Van Vliet G. Hypothyroidism in infants and children. Dans: Braverman LE, Utiger RD (eds). The Thyroid, 9e édition. Lippincott, Williams and Wilkins, 2005; 1029-1047.

Impact of Growth Hormone supplementation on adult height in Turner syndrome: results of the Canadian randomized controlled trial - Stephure DK, Van Vliet G, Deal C, Huot C, The Canadian Growth Hormone Advisory Committee. Impact of Growth Hormone supplementation on adult height in Turner syndrome: results of the Canadian randomized controlled trial. J Clin Endocrinol Metab 2005; 90(6): 3360-3366.

Primary adrenal insufficiency in children: twenty years experience at the Sainte-Justine Hospital, Montreal - Perry RJ, Kecha O, Paquette J, Huot C, Van Vliet G, Deal C. Primary adrenal insufficiency in children: twenty years experience at the Sainte-Justine Hospital, Montreal. J Clin Endocrinol Metab 2005; 90(6): 3243-3250.

Congenital isolated adrenocorticotropin deficiency: an underestimated cause of neonatal death, explained by TPIT gene mutations - Vallette-Kasic S, Brue T, Pulichino A-M, Gueydan M, Barlier A, David M, Nicolino M, Malpuech G, Déchelotte P, Deal C, Van Vliet G, De Vroede M, Riepe FG, Partsch CJ, Sippell WG, Berberoglu M, Atasay B, de Zegher F, Beckers D, Kyllo J, Donohoue P, Fassnacht M, Hahner S, Allolio B, Noordam K, Dunkel L, Hero M, Pigeon B, Weill J, Yigit S, Brauner R, Heinrich JJ, Cummings E, Riddell C, Enjalbert A, Drouin J. Congenital isolated adrenocorticotropin deficiency: an underestimated cause of neonatal death, explained by TPIT gene mutations. J Clin Endocrinol Metab 2005; 90(3): 1323-1331.

How often should we screen children with Down's syndrome for hypothyroidism? - Van Vliet G. How often should we screen children with Down's syndrome for hypothyroidism?. Arch Dis Child 2005; 90(6): 557-558.

Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci - Grasberger H, Mimouni-Bloch A, Vantyghem MC, Van Vliet G, Abramowicz M, Metzger DL, Abdullatif H, Rydlewski C, Macchia PE, Scherberg NH, Van Sande J, Mimouni M, Weiss RE, Vassart G, Refetoff S. Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci. J Clin Endocrinol Metab 2005; 90(7): 4025-4034.

Alu-element insertion in the homeodomain of HESX1 and aplasia of the anterior pituitary - Sobrier M-L, Netchine I, Heinrichs C, Thibaud N, Vie-Luton MP, Van Vliet G, Amselem S. Alu-element insertion in the homeodomain of HESX1 and aplasia of the anterior pituitary. Hum Mutat 2005; 25(5): 503.

Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis - Huang N, Pandey AV, Agrawal V, Reardon W, Lapunzina PD, Mowat D, Jabs EW, Van Vliet G, Sack J, Fluck CE, Miller WL. Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis. Am J Hum Genet 2005; 76(5): 729-749.

Sexual dimorphism of thyroid function in newborns with congenital hypothyroidism - Eugène D, Djemli A, Van Vliet G. Sexual dimorphism of thyroid function in newborns with congenital hypothyroidism. J Clin Endocrinol Metab 2005; 90(5): 2696-2700.

Thyroid radiodioine imaging is superior to ultrasonography in evaluating infants with congenital hypothyroidism (commentaire invité) - Van Vliet G. Thyroid radiodioine imaging is superior to ultrasonography in evaluating infants with congenital hypothyroidism (commentaire invité). Clin Thyroidol 2004; 16: 9.

Screening for neonatal endocrinopathies: rationale, methods and results - Van Vliet G, Czernichow P. Screening for neonatal endocrinopathies: rationale, methods and results. Semin Neonatol 2004; 9(1): 75-85.

Sudden death in growth hormone-treated children with Prader-Willi syndrome - Van Vliet G, Deal C, Crock P, Robitaille Y, Oligny LL. Sudden death in growth hormone-treated children with Prader-Willi syndrome. J Pediatr 2004; 144(1): 129-131.

Molecular mechanisms of normal and abnormal thyroid gland development - Van Vliet G. Molecular mechanisms of normal and abnormal thyroid gland development. Dans: Pescovitz OH, Eugster EE (eds). Pediatric Endocrinology: Mechanisms, Manifestations, and Management. Lippincott Williams and Wilkins, 2004; 479-489.

Hypothyroidism, congenital, long-term follow-up - Dubuis JM, Van Vliet G. Hypothyroidism, congenital, long-term follow-up. Dans: Martini L (ed). Encyclopedia of Endocrine Diseases. Amsterdam. Elsevier Inc., 2004; 728-730.

Reference intervals for free thyroxine, total triiodothyronine, thyrotropin and thyroglobulin for Quebec newborns, children and teenagers - Djemli A, Van Vliet G, Belgoudi J, Lambert MA, Delvin EE. Reference intervals for free thyroxine, total triiodothyronine, thyrotropin and thyroglobulin for Quebec newborns, children and teenagers. Clin Biochem 2004; 37(4): 328-330.

Cognition and behavior at school entry in children with congenital hypothyroidism treated early with high-dose levothyroxine - Simoneau-Roy J, Marti S, Deal C, Huot C, Robaey P, Van Vliet G. Cognition and behavior at school entry in children with congenital hypothyroidism treated early with high-dose levothyroxine. J Pediatr 2004; 144(6): 747-752.

A neonatal form of isolated ACTH deficiency frequently associated with Tpit gene mutations - Vallette-Kasic S, Pulichino A-M, Gueydan M, Barlier A, David M, Malpuech G, Deal C, Van Vliet G, De Vroede M, Riepe FG, Partsch CJ, Sippell WG, Berberoglu M, Atasay B, de Zegher F, Kyllo J, Donohoue P, Déchelotte P, Fassnacht M, Noordam K, Dunkel L, Pigeon B, Weill J, Yigit S, Brauner R, Léger J, Heinrich JJ, Enjalbert A, Brue T, Drouin J. A neonatal form of isolated ACTH deficiency frequently associated with Tpit gene mutations. Endocr Res 2004; 30(4): 943-944.

Lost and found tests: the importance of the hCG stimulation test and other testicular markers to confirm a surgical declaration of anorchia - McEachern RR, Houle AM, Garel L, Van Vliet G. Lost and found tests: the importance of the hCG stimulation test and other testicular markers to confirm a surgical declaration of anorchia. Horm Res 2004; 62: 124-128.

Twenty years later: a reevaluation of the contribution of plasma thyroglobulin to the etiological diagnosis of thyroid dysgenesis in infants with congenital hypothyroidism - Djemli A, Filion M, Belgoudi J, Lambert R, Delvin EE, Schneider W, Van Vliet G. Twenty years later: a reevaluation of the contribution of plasma thyroglobulin to the etiological diagnosis of thyroid dysgenesis in infants with congenital hypothyroidism. Clin Biochem 2004; 37(9): 818-822.

Development of the thyroid gland: lessons from congenitally hypothyroid mice and men - Van Vliet G. Development of the thyroid gland: lessons from congenitally hypothyroid mice and men. Clin Genet 2003; 63: 445-455.

Thyroid disorders in infancy - Van Vliet G. Thyroid disorders in infancy. Dans: Lifshitz F (ed). Pediatric Endocrinology, 4e édition. New York. Marcel Dekker, 2003; 347-358.

Sex-specific impact of congenital hypothyroidism due to thyroid dysgenesis on skeletal maturation in term newborns - Van Vliet G, Larroque B, Bubuteishvili L, Surprenant K, Léger J, on behalf of the Association Française pour le Dépistage et la Prévention des Handicaps de l'Enfant. Sex-specific impact of congenital hypothyroidism due to thyroid dysgenesis on skeletal maturation in term newborns. J Clin Endocrinol Metab 2003; 88(5): 2009-2013.

IGF-1 transcript levels in whole-liver tissue, in freshly isolated hepatocytes, and in cultured hepatocytes from lean and obese Zucker rats - Tenoutasse S, Van Vliet G, Ledru E, Deal C. IGF-1 transcript levels in whole-liver tissue, in freshly isolated hepatocytes, and in cultured hepatocytes from lean and obese Zucker rats. Horm Res 2003; 59(3): 135-141.

Human and mouse TPIT gene mutations cause early onset pituitary ACTH deficiency - Pulichino A-M, Vallette-Kasic S, Couture C, Gauthier Y, Brue T, David M, Malpuech G, Deal C, Van Vliet G, De Vroede M, Riepe FG, Partsch CJ, Sippell WG, Berberoglu M, Atasay B, Drouin J. Human and mouse TPIT gene mutations cause early onset pituitary ACTH deficiency. Gene Dev 2003; 17(6): 711-716.

Thyroid disorders in infancy - Van Vliet G. Thyroid disorders in infancy. Dans: Lifshitz F (ed). Pediatric Endocrinology, 4e édition. New York. Marcel Dekker, 2002; 347-358.

Molecular mechanisms of thyroid gland development: insights from clinical studies and from mutant mice - Van Vliet G. Molecular mechanisms of thyroid gland development: insights from clinical studies and from mutant mice. Dans: Eugster EA, Pescovitz OH (eds). Developmental Endocrinology: From Research to Clinical Practice. Totowa, New Jersey. Humana Press Inc, 2002; 123-134.

Childhood endocrinology - Van Vliet G. Childhood endocrinology. Dans: Shalet SM, Wass JAH (eds). Oxford Textbook of Endocrinology. Oxford University Press, 2002; 949-958.

Hypergonadotropic hypogonadism in a boy with Fanconi's anemia, growth hormone deficiency and pituitary stalk interruption (lettre) - Massa GG, Heinrichs C, Vamos E, Van Vliet G. Hypergonadotropic hypogonadism in a boy with Fanconi's anemia, growth hormone deficiency and pituitary stalk interruption (lettre). J Pediatr 2002; 140(2): 277-278.

Very low birth weight newborns do not need repeat screening for congenital hypothyroidism - Vincent MA, Rodd C, Dussault JH, Van Vliet G. Very low birth weight newborns do not need repeat screening for congenital hypothyroidism. J Pediatr 2002; 140(3): 311-314.

Discordance of monozygotic twins for thyroid dysgenesis: implications for screening and for molecular pathophysiology - Perry RJ, Heinrichs C, Bourdoux P, Khoury K, Szotsz F, Dussault JH, Vassart G, Van Vliet G. Discordance of monozygotic twins for thyroid dysgenesis: implications for screening and for molecular pathophysiology. J Clin Endocrinol Metab 2002; 87(9): 4072-4077.

Anomalies génétiques de l'axe thyréotrope - Van Vliet G, Heinrichs C. Anomalies génétiques de l'axe thyréotrope. Dans: Leclère J, Orgiazzi J, Rousset B, Schlienger JL, Wémeau JL (eds). La Thyroïde, 2e édition. Paris. Elsevier, 2001; 238-244.

Treatment of congenital hypothyroidism - Van Vliet G. Treatment of congenital hypothyroidism. Lancet 2001; 358(9276): 86-87.

US of the pediatric female pelvis: a clinical perspective - Garel L, Dubois J, Grignon A, Filiatrault D, Van Vliet G. US of the pediatric female pelvis: a clinical perspective. Radiographics 2001; 21(6): 1393-1407.

Nine novel mutations in NR0B1 (DAX1) causing adrenal hypoplasia congenita - Zhang YH, Huang BL, Anyane-Yeboa K, Carvalho JA, Clemons RD, Cole T, De Figueiredo BC, Lubinsky M, Metzger DL, Quadrelli R, Repaske DR, Reyno S, Seaver LH, Vaglio A, Van Vliet G, McCabe LL, McCabe ER, Phelan JK. Nine novel mutations in NR0B1 (DAX1) causing adrenal hypoplasia congenita. Hum Mutat 2001; 18(6): 547.

Molecular characterization of a pediatric pheochromocytoma with suspected bilateral disease - Mircescu H, Wilkin F, Paquette J, Oligny LL, Decaluwé H, Gaboury L, Nolet S, Van Vliet G, Deal C. Molecular characterization of a pediatric pheochromocytoma with suspected bilateral disease. J Pediatr 2001; 138(2): 269-273.

A new insight into the molecular basis of 3beta-hydroxysteroid dehydrogenase deficiency - Simard J, Ricketts ML, Moisan AM, Tardy V, Peter M, Van Vliet G, Morel Y. A new insight into the molecular basis of 3beta-hydroxysteroid dehydrogenase deficiency. Endocr Res 2000; 26: 761-770.

Hyperfunctioning malignant thyroid nodule in an eleven-year-old girl: Pathological and molecular study - Mircescu H, Parma J, Huot C, Deal C, Oligny LL, Vassard G, Van Vliet G. Hyperfunctioning malignant thyroid nodule in an eleven-year-old girl: Pathological and molecular study. J Pediatr 2000; 137(4): 585-587.

A novel A10E homozygous mutation in the HSD3B2 gene causing severe salt-wasting 3b-hydroxysteroid dehydrogenase deficiency in 46 XX and 46 XY French Canadians - Alos N, Moisan AM, Ward L, Desrochers M, Legault L, Leboeuf G, Van Vliet G, Simard J. A novel A10E homozygous mutation in the HSD3B2 gene causing severe salt-wasting 3b-hydroxysteroid dehydrogenase deficiency in 46 XX and 46 XY French Canadians. J Clin Endocrinol Metab 2000; 85: 1968-1974.

Congenital central isolated hypothyroidism caused by abnormal TSH due to a homozygous mutation in the TSH-beta subunit gene - Heinrichs C, Parma J, Scherberg NH, Delange F, Van Vliet G, Duprez L, Bourdoux P, Bergmann P, Vassard G, Refetoff S. Congenital central isolated hypothyroidism caused by abnormal TSH due to a homozygous mutation in the TSH-beta subunit gene. Thyroid 2000; 10: 387-391.

Neonatal hypothyroidism: treatment and outcome - Van Vliet G. Neonatal hypothyroidism: treatment and outcome. Thyroid 1999; 9: 79-84.

Managing the short stature of Turner syndrome: an evidence-based approach to the suggestion of growth hormone supplementation - Taback S, Van Vliet G. Managing the short stature of Turner syndrome: an evidence-based approach to the suggestion of growth hormone supplementation. Dans: Hindmarsh PC (ed). Current Indications for Growth Hormone Therapy. 1999; 102-117.

Outcome of Pediatric Graves' Disease after treatment with antithyroid medication and radioiodine - Ward L, Huot C, Lambert R, Deal C, Collu R, Van Vliet G. Outcome of Pediatric Graves' Disease after treatment with antithyroid medication and radioiodine. Clin Invest Med 1999; 22: 132-139.

Pharmacological manipulation of height: qualitative review of study populations and designs - Taback S, Guyda HJ, Van Vliet G. Pharmacological manipulation of height: qualitative review of study populations and designs. Clin Invest Med 1999; 22: 53-59.

A search for the possible molecular mechanisms of thyroid dysgenesis: sex ratios and associated malformations - Devos H, Rodd C, Gagné N, Laframboise R, Van Vliet G. A search for the possible molecular mechanisms of thyroid dysgenesis: sex ratios and associated malformations. J Clin Endocrinol Metab 1999; 84: 2502-2506.

Bases moléculaires de l'hypothyroïdie congénitale - Van Vliet G. Bases moléculaires de l'hypothyroïdie congénitale. Dans: Croissance endocrinologie de l'enfant. Paris. Séminaires Pierre Royer, 1998; 111-116.

Growth hormone supplementation in Turner's Syndrome - Van Vliet G, Deal C. Growth hormone supplementation in Turner's Syndrome. J Pediatr 1998; 133: 803.

Treatment and outcome of neonatal hypothyroidism - Van Vliet G. Treatment and outcome of neonatal hypothyroidism. Dans: Mann K, Pinchera A, Hostalek U (eds). The Thyroid and Age. New York. Schattauer, Stuttgart, 1998; 109-120.

La différentiation sexuelle chez le foetus - Garel L, Van Vliet G. La différentiation sexuelle chez le foetus. P.R.I.S.M.E. 1998; 8(2): 24-32.

Androgens and fetal growth - de Zegher F, François I, Boehmer AL, Saggese G, Muller J, Hiort O, Sultan C, Clayton P, Brauner R, Cacciari E, Ibanez L, Van Vliet G, Tiulpakov A, Saka N, Ritzen M, Sippell WG. Androgens and fetal growth. Horm Res 1998; 50: 243-244.

Decreased growth hormone response to glucagon in infants after an apnea of infancy - Chanoine JP, Rebuffat E, Kahn A, Van Vliet G. Decreased growth hormone response to glucagon in infants after an apnea of infancy. J Pediatr 1998; 132: 452-454.

Apparent congenital athyreosis contrasting with normal plasma thyroglobulin levels and associated with inactivating mutations in the thyrotropin receptor gene: are athyreosis and ectopic thyroid distinct entities? - Gagné N, Parma J, Deal C, Vassart G, Van Vliet G. Apparent congenital athyreosis contrasting with normal plasma thyroglobulin levels and associated with inactivating mutations in the thyrotropin receptor gene: are athyreosis and ectopic thyroid distinct entities?. J Clin Endocrinol Metab 1998; 83: 1171-1175.

Severe congenital hypopituitarism with low prolactin levels and normal pituitary anatomy: A clue to a PIT-I mutation - Ward L, Chavez M, Huot C, Lecoq P, Collu R, Décarie JC, Martial JA, Van Vliet G. Severe congenital hypopituitarism with low prolactin levels and normal pituitary anatomy: A clue to a PIT-I mutation. J Pediatr 1998; 132(6): 1036-1038.

Brief report: central hypothyroidism caused by inactivating mutations in the thyrotropin-releasing hormone receptor gene - Collu R, Tang J, Castagné J, Lagacé G, Masson N, Huot C, Deal C, Delvin EE, Faccenda E, Eidne K, Van Vliet G. Brief report: central hypothyroidism caused by inactivating mutations in the thyrotropin-releasing hormone receptor gene. J Clin Endocrinol Metab 1997; 82: 1561-1565.

Diversity and prevalence of somatic mutations in the TSH receptor and Gsa genes as causes of toxic thyroid adenomas - Parma J, Duprez L, Van Sande J, Hermans J, Rocmans P, Van Vliet G, Costagliola S, Rodien P, Dumont J, Vassart G. Diversity and prevalence of somatic mutations in the TSH receptor and Gsa genes as causes of toxic thyroid adenomas. J Clin Endocrinol Metab 1997; 82: 2695-2701.

Altered mRNA expression due to insertion or substitution of thymine at position +3 or two splice-donor sites in the androgen receptor gene - Trifiro MA, Lumbroso R/Beitel LK, Vasikiou DM, Bouchard J, Deal C, Van Vliet G, Pinsky L. Altered mRNA expression due to insertion or substitution of thymine at position +3 or two splice-donor sites in the androgen receptor gene. Eur J Hum Genet 1997; 5: 50-58.

Endocrine therapy in Turner syndrome. (Letter to the editor) - Taback S, Deal C, Van Vliet G. Endocrine therapy in Turner syndrome. (Letter to the editor). N Engl J Med 1997; 336: 1527.

Growth hormone treatment and adult height in Turner syndrome: do we need controlled studies? - Van Vliet G. Growth hormone treatment and adult height in Turner syndrome: do we need controlled studies?. Dans: Rovet J (ed). Turner Syndrome Across the Life Span. Markham, Ontario. Klein Graphics, 1996; 76-80.

Outcome of severe congenital hypothyroidism: closing the developmental gap with early high dose levothyroxine treatment - Dubuis JM, Glorieux J, Richer F, Deal C, Dussault JH, Van Vliet G. Outcome of severe congenital hypothyroidism: closing the developmental gap with early high dose levothyroxine treatment. J Clin Endocrinol Metab 1996; 81: 222-227.

Effects of 14-day infusions of growth hormone (GH) and/or insulin-like growth factor I on the obesity of growing Zucker rats - Dubuis JM, Deal C, Van Vliet G. Effects of 14-day infusions of growth hormone (GH) and/or insulin-like growth factor I on the obesity of growing Zucker rats. Endocrinology 1996; 137: 2799-2806.

Does growth hormone supplementation affect adult height in Turner syndrome? - Taback S, Collu R, Deal C, Guyda HJ, Salisbury S, Dean H, Van Vliet G. Does growth hormone supplementation affect adult height in Turner syndrome?. Lancet 1996; 348: 25-27.

Somatostatin analog pretreatment enhances growth hormone (GH) responsiveness to GH releasing hormone (GHRH): potential efficacy in the diagnosis of GH deficiency - Tzanella M, Guyda HJ, Van Vliet G, Tannenbaum GS. Somatostatin analog pretreatment enhances growth hormone (GH) responsiveness to GH releasing hormone (GHRH): potential efficacy in the diagnosis of GH deficiency. J Clin Endocrinol Metab 1996; 81: 2487-2494.

Mortality in Canadian children with growth hormone (GH) deficiency receiving GH therapy 1967-1992 - Taback S, Dean H, and members of the Canadian Growth Hormone Advisory Committee, Deal C, Van Vliet G. Mortality in Canadian children with growth hormone (GH) deficiency receiving GH therapy 1967-1992. J Clin Endocrinol Metab 1996; 81: 1693-1696.

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