Chercheur

    Jacques Lacroix , M.D.

    jacques_lacroix@ssss.gouv.qc.ca
    Jacques Lacroix
    Axe de recherche
    Santé métabolique et maladies complexes
    Thème de recherche
    Soins aigus et médecine transfusionnelle
    Adresse
    CHUSJ

    Téléphone
    514 345-4931 #5549

    Titres

    • Professeur titulaire, Département de pédiatrie, Université de Montréal.
    • Membre, Service des soins intensifs pédiatriques, CHU Sainte-Justine.
    • Responsable, Axe Avancement et devenir en santé, Centre de recherche CHU Sainte-Justine.

    Formation

    • Soins intensifs pédiatriques, Université René Descartes, Paris, 1979-1980.
    • Pédiatrie (FRCPC, FAAP), Université de Montréal, 1974-1978.
    • MD, Université de Montréal, 1969-1974.

    Intérêts de recherche

    • Recherches sur les produits sanguins tels que les concentrés globulaires, ainsi que sur la prévention des transfusions.
    • Sepsis et syndrome de défaillance multiviscérale (SDMV; multiple organ dysfunction syndrome ou MODS en anglais). Nous nous intéressons à la physiopathologie du sepsis et du SDMV, à leurs facteurs de risque, à leur impact clinique, à leur traitement et à leur prévention. Nous avons créé et validé une échelle clinimétrique permettant de mesurer la gravité des cas de SDMV, le Pediatric Logistic Organ Dysfunction (PELOD) score.
    • Traumatologie pédiatrique (traumatisme crânien grave en particulier).
    • Infections nosocomiales en réanimation pédiatrique.

    Prix et distinctions

    • Prix de l’enseignement, Comité des ressources humaines du Conseil d’administration, Programme de reconnaissance du CHU Sainte-Justine, novembre 2007.
    • Programme de reconnaissance pour le développement de la recherche clinique, Centre de recherche CHU Sainte-Justine, 2003-2004.
    • Prix d’excellence en enseignement des études médicales postscolaires pour l’année 2001-2002, Faculté de médecine, Université de Montréal, juin 2002.

Publications

Weaning children from mechanical ventilation with a computer-driven protocol: a pilot trial - Jouvet P, Payen V, Gauvin F, Emeriaud G, Lacroix J. Weaning children from mechanical ventilation with a computer-driven protocol: a pilot trial. Intensive Care Med 2013; 39(5): 919-925.

Clinical equipoise regarding clycemic control: a aurvey of pediatric intensivist perceptions - Hirschberg E, Sward K, Faustino EV, Nadkarni VM, Agus MS, Morris A, Lacroix J. Clinical equipoise regarding clycemic control: a aurvey of pediatric intensivist perceptions. Pediatr Crit Care Med 2013; 14(2): 123-129.

Excess of veno-occlusive disease in a randomized clinical trial on a higher trigger for red blood cell transfusion after bone marrow transplantation: a Canadian Blood and Marrow Transplant Group Trial - Robitaille N, Lacroix J, Alexandrov L, Clayton L, Cortier M, Schultz KR, Bittencourt H, Duval M. Excess of veno-occlusive disease in a randomized clinical trial on a higher trigger for red blood cell transfusion after bone marrow transplantation: a Canadian Blood and Marrow Transplant Group Trial. Biol Blood Marrow Tr 2013; 19(3): 468-473.

Association between plasma transfusions and clinical outcome in critically ill children: a prospective observational study - Karam O, Lacroix J, Robitaille N, Rimensberger P, Tucci M. Association between plasma transfusions and clinical outcome in critically ill children: a prospective observational study. Vox Sang 2013; 104(4): 342-349.

Modes of death in pediatrics: differences in the ethical approach in neonatal and pediatric patients - Fontana M, Farrell CA, Gauvin F, Lacroix J, Janvier A. Modes of death in pediatrics: differences in the ethical approach in neonatal and pediatric patients. J Pediatr 2013; 162(6): 1107-1111.

Does prolonged red cell storage affect outcomes in the critically ill? - Lacroix J, Hébert P. Does prolonged red cell storage affect outcomes in the critically ill?. Am J Respir Crit Care Med 2012; 185(8): 798-788.

Noninvasive or invasive hemoglobin measurement? - Lacroix J, Tucci M. Noninvasive or invasive hemoglobin measurement?. Crit Care Med 2012; 40(9): 2715-2716.

Red blood cell transfusion: decision making in pediatric intensive care units - Lacroix J, Demaret P, Tucci M. Red blood cell transfusion: decision making in pediatric intensive care units. Semin Perinatol 2012; 36(4): 225-231.

Transfusion medicine - Tucci M, Lacroix J, Gauvin F, Toledano B, Robitaille N. Transfusion medicine. Dans: Wheeler DS, Wong HR, Shaley TP(eds). Pediatric Critical Care Medicine: Basic science and clinical evidence, 2nd edition. London. Springer-Verlag, 2012; (sous presse).

The role of comparative effectiveness research in transfusion medicine clinical trials: proceedings of a National Heart, Lung, and Blood Institute workshop - Blajchman M, Carson JL, Eikelboom JW, Heddle NM, Lacroix J, Lauer MS, Platt RW, Tilley B, Triulzi D, Vickers AJ, Yusuf S, Glynn S, Mondoro TH, Wagner É. The role of comparative effectiveness research in transfusion medicine clinical trials: proceedings of a National Heart, Lung, and Blood Institute workshop. Transfusion 2012; 52(6): 1363-1378.

Could organ dysfunctions and other morbidity measures be misleading - Karam O, Tucci M, Ducruet T, Hume HA, Lacroix J, Gauvin F. Could organ dysfunctions and other morbidity measures be misleading. Pediatr Crit Care Med 2012; 13: 495.

Hemoglobin levels and transfusions in neurocritically ill patients: a systematic review of comparative studies - Desjardins P, Turgeon A, Tremblay M, Lauzier F, Zarychanski R, Boutin A, Moore L, McIntyre L, English SW, Rigamonti A, Lacroix J, Ferguson D. Hemoglobin levels and transfusions in neurocritically ill patients: a systematic review of comparative studies. Crit Care 2012; 16: R54 doi:10.1186/cc11293.

Mortality associated with restrictive threshold for red blood cell transfusion in pediatric patients with sepsis - Karam O, Tucci M, Ducruet T, Hume HA, Lacroix J, Gauvin F. Mortality associated with restrictive threshold for red blood cell transfusion in pediatric patients with sepsis. Pediatr Crit Care Med 2012; 13(4): 495: doi: 10.1097/PCC.0b013e31824fbefe.

Transfusion-related Epstein-Barr virus infection among stem cell transplant recipients: a retrospective cohort study in children - Trottier H, Buteau C, Robitaille N, Duval M, Tucci M, Lacroix J, Alfieri C. Transfusion-related Epstein-Barr virus infection among stem cell transplant recipients: a retrospective cohort study in children. Transfusion 2012; 52(12): 2653-2663.

Struggling to do what is right for the child: Pediatric life-support decisions among physicians and nurses in France and Quebec - Carnevale F, Farrell CA, Cremer R, Canoui P, Séguret S, Gaudreault J, de Bérail B, Lacroix J, Leclerc F, Hubert P. Struggling to do what is right for the child: Pediatric life-support decisions among physicians and nurses in France and Quebec. J Child Health Care 2012; 16(2): 109-123.

Risk factors associated with increased length of mechanical ventilation in children - Payen V, Jouvet P, Lacroix J, Ducruet T, Gauvin F. Risk factors associated with increased length of mechanical ventilation in children. Pediatr Crit Care Med 2012; 13(2): 152-157.

Transfusion medicine - Lacroix J, Tucci M, Tinmouth A, Gauvin F, Karam O. Transfusion medicine. Dans: Fuhrman BP, Zimmerman JJ (eds). Pediatric Critical Care, 4th edition. Toronto (Ontario). Elsevier, 2011; 1162-1176.

The Age of Blood Evaluation (ABLE) randomized controlled trial: study design - Lacroix J, Hébert P, Fergusson DM, Tinmouth A, Blajchman M, Callum J, Cook D, Marshall JC, McIntyre L, Turgeon A, ABLE study group. The Age of Blood Evaluation (ABLE) randomized controlled trial: study design. Transf Med Rev 2011; 25(3): 197-205.

[Clinical impact of length of storage before red blood cell transfusion] - Lacroix J, Tucci M. [Clinical impact of length of storage before red blood cell transfusion]. Transfus Clin Biol 2011; 18(2): 97-105.

Effects and outcomes associated with red blood cell storage age - Spinella PC, Lacroix J, Tucci M. Effects and outcomes associated with red blood cell storage age. Dans: Spinella PC, Nadkarni VM (eds). Current Concepts in Pediatric Critical Care Course. Des Plaines. Society of Critical Care Medicine, 2011; 41-49.

Hematology and oncology in children - Emeriaud G, Lacroix J. Hematology and oncology in children. Dans: Vincent J-L, Abraham E, Kochanek P, Moore FA, Fink MP (eds). Textbook of Critical Care, 6th edition. Philadelphia, PA. Elsevier, 2011; 1168-1171.

Red cell transfusion in pediatric cardiac patients: fact and fallacies - Toledano B, Tucci M, Lacroix J. Red cell transfusion in pediatric cardiac patients: fact and fallacies. Pediatr Crit Care Med 2011; 12(1): 107-108.

Red blood cell transfusion thresholds in pediatric patients with sepsis - Karam O, Tucci M, Ducruet T, Hume HA, Lacroix J, Gauvin F, for the Canadian Critical Care Trials Group, and the PALISI Network. Red blood cell transfusion thresholds in pediatric patients with sepsis. Pediatr Crit Care Med 2011; 12(5): 512-518.

Targeted temperature management in critical care: a report and recommendations from five professional societies - Nunnally ME, Jaeschke R, Bellingan GJ, Lacroix J, Mourvillier B, Rodriguez-Vega GM, Rubertsson S, Vassilakopoulos T, Weinert C, Zanotti-Cavazzoni S, Buchman TG. Targeted temperature management in critical care: a report and recommendations from five professional societies. Pediatr Crit Care Med 2011; 39(5): 1113-1125.

Developmental outcome after a single episode of status epilepticus - Roy H, Lippé S, Lussier F, Sauerwein HC, Lortie A, Lacroix J, Lassonde M. Developmental outcome after a single episode of status epilepticus. Epilepsy Behav 2011; 21(4): 430-436.

Red blood cell transfusion and increased length of storage are not associated with deep vein thrombosis in medical and surgical critically ill patients: a prospective observational cohort study - Katsios C, Griffith L, Spinella P, Lacroix J, Crowther M, Hébert P, Meade M, Geerts W, Rabbat C, Cook D. Red blood cell transfusion and increased length of storage are not associated with deep vein thrombosis in medical and surgical critically ill patients: a prospective observational cohort study. Crit Care 2011; 15(6): R263 doi: 10.1186/cc10526.

LRPPRC mutations cause a phenotypically distinct form of Leigh syndrome with cytochrome c oxidase deficiency - Debray FG, Morin C, Janvier A, Villeneuve J, Maranda B, Laframboise R, Lacroix J, Décarie JC, Robitaille Y, Lambert MA, Robinson BH, Mitchell GA. LRPPRC mutations cause a phenotypically distinct form of Leigh syndrome with cytochrome c oxidase deficiency. J Med Genet 2011; 48(3): 183-189.

Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum - Fraser DD, Close TE, Rose KL, Ward R, Mehl M, Farrell CA, Lacroix J, Creery D, Kesselman M, Stanimirovic D, Hutchison JS, for the Canadian Critical Care Translational Biology Group. Severe traumatic brain injury in children elevates glial fibrillary acidic protein in cerebrospinal fluid and serum. Pediatr Crit Care Med 2011; 12(3): 319-324.

Transfuser ou ne pas transfuser: Un choix déterminant pour les enfants hospitalisés en service de soins intensifs. [Improving use of red-cell transfusion in pediatric intensive care units] - Lacroix J, Trottier H, Tucci M. Transfuser ou ne pas transfuser: Un choix déterminant pour les enfants hospitalisés en service de soins intensifs. [Improving use of red-cell transfusion in pediatric intensive care units]. Médecine Sciences 2010; 25(11): 963-965.

Improving interhospital paediatric transport - Jouvet P, Lacroix J. Improving interhospital paediatric transport. Lancet 2010; 376(9742): 660-661.

Treatment of severe paediatric traumatic brain injury by hypothermia: pros and cons - Beauchamp MH, Hutchison JS, Lacroix J. Treatment of severe paediatric traumatic brain injury by hypothermia: pros and cons. Réanimation 2010; 19(7): 665-670.

Cardiac arrhythmias associated with severe traumatic brain injury and hypothermia therapy - Bourdages M, Bigras JL, Farrell CA, Hutchison JS, Lacroix J, Canadian Critical Care Trials Group. Cardiac arrhythmias associated with severe traumatic brain injury and hypothermia therapy. Pediatr Crit Care Med 2010; 11(3): 408-414.

Daily estimation of the severity of multiple organ dysfunction syndrome in critically ill children - Leteurtre S, Duhamel A, Grandbastien B, Proulx F, Cotting J, Gottesman R, Joffe A, Wagner B, Hubert P, Martinot A, Lacroix J, Leclerc F. Daily estimation of the severity of multiple organ dysfunction syndrome in critically ill children. CMAJ 2010; 182(11): 1181-1187.

Red blood cell transfusion threshold in postsurgical pediatric intensive care patients: A randomized clinical trial - Rouette J, Trottier H, Ducruet T, Beaunoyer M, Lacroix J, Tucci M, for the Canadian Critical Care Trials Group, and the PALISI Network. Red blood cell transfusion threshold in postsurgical pediatric intensive care patients: A randomized clinical trial. Ann Surg 2010; 251(3): 421-427.

Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis - Willems A, Harrington K, Lacroix J, Biarent D, Joffe A, Wensley D, Ducruet T, Hébert P, Tucci M, TRIPICU investigators, Canadian Critical Care Trials Group, for the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Comparison of two red-cell transfusion strategies after pediatric cardiac surgery: a subgroup analysis. Crit Care Med 2010; 38(2): 649-656.

Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study - Karam O, Tucci M, Bateman ST, Ducruet T, Spinella PC, Randolph AG, Lacroix J. Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study. Crit Care 2010; 14(2): R57.

Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients - Gauvin F, Spinella PC, Lacroix J, Choker G, Ducruet T, Karam O, Hébert P, Hutchison JS, Hume HA, Tucci M. Association between length of storage of transfused red blood cells and multiple organ dysfunction syndrome in pediatric intensive care patients. Transfusion 2010; 50(9): 1902-1913.

Survey of transfusion policies at US and Canadian children's hospitals in 2008 and 2009 - Spinella PC, Dressler A, Tucci M, Carroll CL, Rosen RS, Hume HA, Sloan SR, Lacroix J, for the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Survey of transfusion policies at US and Canadian children's hospitals in 2008 and 2009. Transfusion 2010; 50(11): 2328-2335.

Impact of hypotension and low cerebral perfusion pressure on outcomes in children treated with hypothermia therapy following severe traumatic brain injury: a post hoc analysis of the Hypothermia Pediatric Head Injury Trial - Hutchison JS, Frndova H, Lo TY, Guerguerian A-M, Farrell CA, Lacroix J, Hyperthermia Pediatric Head Injury Trial Investigators, Canadian Critical Care Trials Group. Impact of hypotension and low cerebral perfusion pressure on outcomes in children treated with hypothermia therapy following severe traumatic brain injury: a post hoc analysis of the Hypothermia Pediatric Head Injury Trial. Dev Neurosci 2010; 32(5-6): 406-412.

Differences in organ dysfunctions between neonates and older children: a prospective, observational, multicenter study - Bestati N, Leteurtre S, Duhamel A, Proulx F, Grandbastien B, Lacroix J, Leclerc F. Differences in organ dysfunctions between neonates and older children: a prospective, observational, multicenter study. Crit Care 2010; 14(6): R202 doi: 10.1186/cc9323.

A review of the TRIPICU study and clinical implications - Lacroix J, Tucci M. A review of the TRIPICU study and clinical implications. Minerva Anestesiol 2009; 75(supp. 1): 791-793.

[Improving use of red-cell transfusion in pediatric intensive care units] - Lacroix J, Tucci M, Trottier H. [Improving use of red-cell transfusion in pediatric intensive care units]. Méd Sci (Paris) 2009; 25(11): 963-966.

Should we avoid transfusion inthe pediatric intensive care unit? - Gauvin F, Lacroix J. Should we avoid transfusion inthe pediatric intensive care unit?. Pediatr Crit Care Med 2009; 10(3): 400-401.

Critically ill patients with novel swine origin influenza virus A/H1N1 infection in Canada - Kumar A, Zarychanski R, Pinto R, Cook D, Marshall J, Lacroix J, Stelfox T, Bagshaw S, Choong K, Lamontagne F, Turgeon A, Lapinsky S, Ahern SP, Smith O, Siddiqui F, Jouvet P, Khwaja K, McIntyre L, Menon K, Hutchison J, Hornstein D, Joffe A, Lauzier F, Singh J, Karachi T, Wiebe K, Olafson K, Ramsey C, Sharma S, Dodek P, Meade M, Hall R, Fowler R, for the Canadian Critical Care Trials Group H1N1 Collaborative. Critically ill patients with novel swine origin influenza virus A/H1N1 infection in Canada. JAMA 2009; 302(17): 1872-1879.

Length of storage and in vitro immunomodulation induced by prestorage leukoreduced red blood cells - Karam O, Tucci M, Toledano B, Robitaille N, Cousineau J, Thibault L, Lacroix J, Le Deist F. Length of storage and in vitro immunomodulation induced by prestorage leukoreduced red blood cells. Transfusion 2009; 49(11): 2326-2334.

Hypothermia therapy after pediatric cardiac arrest - Doherty DR, Parshuram CS, Gaboury I, Hoskote A, Lacroix J, Tucci M, Joffe A, Choong K, Farrell R, Bohn D, Hutchison JS, and the Canadian Critical Care Trials Group. Hypothermia therapy after pediatric cardiac arrest. Circulation 2009; 119(11): 1492-1500.

Children with chronic conditions in pediatric intensive care units located in predominantly French-speaking regions: Prevalence and implications on rehabilitation care need and utilization - Cremer R, Leclerc F, Lacroix J, Ploin D, Emeriaud G, GFRUP/RMEF Chronic Diseases in PICU Study Group. Children with chronic conditions in pediatric intensive care units located in predominantly French-speaking regions: Prevalence and implications on rehabilitation care need and utilization. Crit Care Med 2009; 37(4): 1456-1462.

The pediatric multiple organ dysfunction syndrome - Proulx F, Joyal JS, Maricelsco MM, Leteurtre S, Leclerc F, Lacroix J. The pediatric multiple organ dysfunction syndrome. Pediatr Crit Care Med 2009; 10(1): 12-22.

Anemia, blood loss, and blood transfusions in North American children in the intensive care unit - Bateman ST, Lacroix J, Boven K, Forbes P, Barton R, Thomas N, Jacobs B, Markovitz B, Goldstein B, Hanson JH, Li HA, Randolph AG, and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Anemia, blood loss, and blood transfusions in North American children in the intensive care unit. Am J Respir Crit Care Med 2008; 178(1): 26-33.

Hypothermia therapy after traumatic brain injury in children - Hutchison S, Lacroix J, Hébert P. Hypothermia therapy after traumatic brain injury in children. N Engl J Med 2008; 359(11): 1180.

Blood products in the PICU - Lacroix J, Luban N, Wong E. Blood products in the PICU. Dans: Nichols DG (eds). Rogers Textbook of Pediatric Intensive Care. Philadelphia. Wolters Kluwer/Lippincott Williams & Wilkins, 2008; 584-599.

Life-support technologies - Dalton H, Lacroix J. Life-support technologies. Dans: Nichols DG (eds). Rogers Textbook of Pediatric Intensive Care. Philadelphia. Wolters Kluwer/Lippincott Williams & Wilkins, 2008; 508-511.

Blood glucose control in critically ill adults and children: a survey on stated practice - Hirschberg E, Lacroix J, Sward K, Willson D, Morris A. Blood glucose control in critically ill adults and children: a survey on stated practice. Chest 2008; 133(6): 1328-1335.

Severity injury mechanisms in two pediatric trauma centres: Determination of prevention priorities - Cyr C, Xhignesse M, Lacroix J. Severity injury mechanisms in two pediatric trauma centres: Determination of prevention priorities. Paediatr Child Health 2008; 13(1): 165-172.

Hypothermia therapy after traumatic brain injury in children - Hutchison JS, Ward R, Lacroix J, Hébert P, Barnes M, Bohn D, Dirks P, Doucette S, Fergusson DM, Gottesman R, Joffe A, Kirpalani H, Meyer P, Morris K, Moher D, Singh R, Skippen P, Farrell CA, Hyperthermia Pediatric Head Injury Trial Investigators, and the Canadian Critical Care Trials Group. Hypothermia therapy after traumatic brain injury in children. N Engl J Med 2008; 358(23): 2447-2256.

Procalcitonin and C-reactive protein as markers of bacterial infection in critically ill children at onset of systemic inflammatory response syndrome - Simon L, St-Louis P, Amre D, Lacroix J, Gauvin F. Procalcitonin and C-reactive protein as markers of bacterial infection in critically ill children at onset of systemic inflammatory response syndrome. Pediatr Crit Care Med 2008; 9(4): 407-413.

Transfusion strategies for patients in pediatric intensive care units - Lacroix J, Hébert P, Hutchison JH, Hume HA, Tucci M, Ducruet T, Gauvin F, Collet JP, Toledano B, Robillard P, Joffe A, Biarent D, Meert K, Peters MJ, on behalf of the TRIPICU investigators, for the Canadian Critical Care Trial Group, and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Transfusion strategies for patients in pediatric intensive care units. N Engl J Med 2007; 356(16): 1609-1619.

Le syndrome de défaillance multiviscérale chez l'enfant: étiopathogénie (Pediatric multiple organ dysfunction syndrome: physiopathology) - Lacroix J, Proulx F. Le syndrome de défaillance multiviscérale chez l'enfant: étiopathogénie (Pediatric multiple organ dysfunction syndrome: physiopathology). Dans: Brissaud O (ed). Actualités en Réanimation et Urgences. Paris. Elsevier, 2007; 580-591.

Transfusion in pediatric intensive care units: reply to letter to the editor - Lacroix J, Tucci M, Gauvin F. Transfusion in pediatric intensive care units: reply to letter to the editor. N Engl J Med 2007; 357: 302.

Stridor - Lacroix J, Giguère C. Stridor. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 1168-1172.

Insuffisance respiratoire aiguë - Lacroix J. Insuffisance respiratoire aiguë. Dans: Turgeon J, Bernard-Bonnin AC, Gervais P, Ovetchkine P, Gauthier M (eds). Dictionnaire de thérapeutique pédiatrique Weber, 2e édition. Boucherville. Gaëtan Morin, 2007; 749-755.

Urgences et soins intensifs pédiatriques - Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P, e. Urgences et soins intensifs pédiatriques. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 1368 pages.

Les soins intensifs pédiatriques - Lacroix J. Les soins intensifs pédiatriques. Dans: Roy CC (éd). La petite histoire de Ste-Justine 1907-2007. Montréal. Éditions du CHU Ste-Justine, 2007; 210-214.

What tests can help diagnose and estimate the severity of sepsis? - Lacroix J. What tests can help diagnose and estimate the severity of sepsis?. J Pediatr 2007; 83(4): 297-298.

Red blood cell transfusion in pediatric ICU - Lacroix J, Tucci M, Gauvin F. Red blood cell transfusion in pediatric ICU. Dans: Vincent JL (ed.). Yearbook of intensvie care and emergency medicine. Heidelberg. Springer-Verlag, 2007; 813-822.

Transfusion medicine - Lacroix J, Tucci M, Gauvin F, Toledano B, Hume HA. Transfusion medicine. Dans: Wheeler DS, Wong HR, Shaley TP(eds). Pediatric Critical Care Medicine: Basic science and clinical evidence. London. Springer-Verlag, 2007; 1263-1280.

Obstruction grave des voies aériennes supérieures - Lacroix J, Fayoux P, Caouette-Laberge L. Obstruction grave des voies aériennes supérieures. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 295-317.

Traumatisme de la moelle cervicale - Meyer D, Lacroix J, Mercier C. Traumatisme de la moelle cervicale. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 933-945.

Sepsis et choc septique - Leclerc F, Lacroix J, Proulx F, Tapiero B, Hazelzet J. Sepsis et choc septique. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 211-240.

Acute lung injury: is volume the question? - Jouvet P, Lacroix J. Acute lung injury: is volume the question?. Pediatr Crit Care Med 2007; 8(4): 397-398.

Inspiratory muscle unloading by neurally adjusted ventilatory assist during maximal inspiratory efforts in healthy subjects - Sinderby C, Beck J, Spahija J, De Marchie M, Lacroix J, Navalesi P, Slutsky AS. Inspiratory muscle unloading by neurally adjusted ventilatory assist during maximal inspiratory efforts in healthy subjects. Chest 2007; 131(3): 711-717.

Risk factors of acute renal failure in critically ill children: a prospective descriptive epidemiological study - Bailey D, Phan V, Litalien C, Ducruet T, Mérouani A, Lacroix J, Gauvin F. Risk factors of acute renal failure in critically ill children: a prospective descriptive epidemiological study. Pediatr Crit Care Med 2007; 8(1): 29-35.

Parental involvement in treatment decisions regarding their critically ill child: a comparative study of France and Quebec - Carnevale F, Canoui P, Cremer R, Farrell CA, Doussau A, Séguin MJ, Hubert P, Leclerc F, Lacroix J. Parental involvement in treatment decisions regarding their critically ill child: a comparative study of France and Quebec. Pediatr Crit Care Med 2007; 8(4): 337-342.

Étude comparative, en France et au Québec, de la place des parents lors des décisions de limitation des traitements en réanimation pédiatrique - Carnevale F, Farrell CA, Canoui P, Cremer R, Séguin MJ, Leclerc F, Hubert P, Lacroix J. Étude comparative, en France et au Québec, de la place des parents lors des décisions de limitation des traitements en réanimation pédiatrique. Médecine Palliative 2007; 6: 78-79.

Principes de pharmacologie en réanimation pédiatrique - Tréluyer JM, Gaudreault P, Lacroix J. Principes de pharmacologie en réanimation pédiatrique. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 1017-1032.

Intoxication: généralités - Gaudreault P, Cremer R, Lacroix J, Lheureux P. Intoxication: généralités. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 1033-1049.

Mesures physiologiques et scores de gravité - Fayon M, Leclerc F, Leteurtre S, Roze JC, Lacroix J, Meyer P. Mesures physiologiques et scores de gravité. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 1265-1292.

Soins post-opératoires de chirurgie cardiaque - Houde C, Biarent D, Da Cruz E, Toledano B, Vobecky S, Lacroix J. Soins post-opératoires de chirurgie cardiaque. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 483-513.

Hémorragie digestive haute - Faure C, Chaïbou M, Lacroix J. Hémorragie digestive haute. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 705-719.

Syndrome de défaillance multiviscérale - Proulx F, Leteurtre S, Leclerc S, Lacroix J, Van den Berghe G, Vanasse M. Syndrome de défaillance multiviscérale. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 143-165.

État de mal convulsif - Gaillot T, Carmant L, Guillois B, Mitchell GA, Lacroix J, Gaudreault P, Rousseau E. État de mal convulsif. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 613-631.

Acceptable respiratory physiological limits for children during the weaning phase of mechanical ventilation - Santschi M, Gauvin F, Hatzakis G, Lacroix J, Jouvet P. Acceptable respiratory physiological limits for children during the weaning phase of mechanical ventilation. Intensive Care Med 2007; 33(2): 319-325.

Incidence of deep vein thrombosis related to peripherally inserted central catheters (PICC) in children - Dubois J, Rypens FF, Garel L, David M, Lacroix J, Gauvin F. Incidence of deep vein thrombosis related to peripherally inserted central catheters (PICC) in children. CMAJ 2007; 177(10): 1185-1190.

Choc hémorragique - Orliaguet G, Gauvin F, Hume HA, Lacroix J, Hébert P. Choc hémorragique. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 167-186.

Assistance respiratoire - Jouvet P, Leclerc F, Rimensberger P, Morneau S, Hatzakis G, Tucci M, Robert D, Bougatef A, Lacroix J. Assistance respiratoire. Dans: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds). Urgences et soins intensifs pédiatriques. Montréal et Paris. Éditions du CHU Sainte-Justine et Elsevier Masson, 2007; 35-61.

Acute transfusion reactions in pediatric intensive care unit - Gauvin F, Lacroix J, Robitaille P, Lapointe H, Hume HA. Acute transfusion reactions in pediatric intensive care unit. Transfusion 2006; 46(11): 1899-1908.

Nosocomial infection in the Pediatric Intensive Care Unit: Epidemioloy and control - Lacroix J, Gauvin F, Skippen P, Cox P, Langley JM, Matlow A. Nosocomial infection in the Pediatric Intensive Care Unit: Epidemioloy and control. Dans: Fuhrman BP, Zimmerman JJ (eds). Pediatric Critical Care, 3rd edition. St-Louis. Mosby Year Book, 2006; 1294-1342.

Erythropoietin in PICU: Is it appropriate therapy? - Tucci M, Lacroix J. Erythropoietin in PICU: Is it appropriate therapy?. Pediatr Crit Care Med 2006; 7(6): 607-608.

Goal-directed blood transfusion therapies - Tucci M, Lacroix J. Goal-directed blood transfusion therapies. Dans: Nadkarni VM (ed). Current Concepts in Pediatric Critical Care Course. Des Plaines. Society of Critical Care Medicine, 2006; 103-120.

Limitation in paediatric logistic organ dysfunction (PELOD) score - Leteurtre S, Duhamel A, Grandbastien B, Lacroix J, Leclerc F. Limitation in paediatric logistic organ dysfunction (PELOD) score. Lancet 2006; 368: 1051; author reply 1051-1052.

Diaphragm electrical activity during expiration in mechanically ventilated infants - Emeriaud G, Beck J, Tucci M, Lacroix J, Sinderby C. Diaphragm electrical activity during expiration in mechanically ventilated infants. Pediatr Res 2006; 59(5): 705-710.

Paediatric logistic organ dysfunction (PELOD) score - Leteurtre S, Duhamel A, Grandbastien B, Lacroix J, Leclerc F. Paediatric logistic organ dysfunction (PELOD) score. Lancet 2006; 367(9514): 897; author reply 900-902.

Diaphragm electrical activity during expiration in mechanically ventilated infants - Emeriaud G, Beck J, Tucci M, Lacroix J, Sinderby C. Diaphragm electrical activity during expiration in mechanically ventilated infants. Pediatr Res 2006; 59(5): 705-710.

Hypothermia pediatric head injury trial: the value of a pretrial clinical evaluation - Hutchison J, Ward R, Lacroix J, Hébert P, Skippen P, Barnes M, Meyer P, Morris K, Kirpalani H, Singh R, Dirks P, Bohn D, Moher D, Farrell CA, and the Canadian Critical Care Trial Group. Hypothermia pediatric head injury trial: the value of a pretrial clinical evaluation. Dev Neurosci 2006; 28: 291-301.

The moral experience of parents regarding life-support decisions for their critically-ill children: a preliminary study in France - Carnevale F, Canoui P, Hubert P, Farrell CA, Leclerc F, Doussau A, Séguin MJ, Lacroix J. The moral experience of parents regarding life-support decisions for their critically-ill children: a preliminary study in France. J Child Health Care 2006; 10(1): 69-82.

When the brain is injured, the body suffers - Lacroix J, Toledano B. When the brain is injured, the body suffers. Crit Care Med 2005; 33(3): 697-698.

Severity of illness and organ dysfunction scoring in children - Lacroix J, Cotting J, for the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Severity of illness and organ dysfunction scoring in children. Crit Care Med 2005; 6(suppl. 3): S126-S134.

Transfusion of blood products: When, why and how - Lacroix J, Hume HA, Gauvin F, Severinii MH. Transfusion of blood products: When, why and how. Dans: Piva JP, Garcia PCR (eds). Medicina intensiva em Pediatra, 5e édition. Rio de Janiero. Editora Medsi, 2005; 216-246.

Hematology and oncology in children - Emeriaud G, Lacroix J. Hematology and oncology in children. Dans: Fink MP, Abraham E, Kochanek PM, Vincent JL (eds). Textbook of Critical Care, 5th edition. Philadelphia, PA. Elsevier, 2005; 1471-1475.

PICU mortality: It is better 9 to 5? - Tucci M, Lacroix J. PICU mortality: It is better 9 to 5?. Pediatr Crit Care Med 2005; 6(5): 608-609.

International Pediatric Sepsis Consensus Conference: Definitions for sepsis and organ dysfunction in pediatrics - Goldstein B, Giroir B, Randolph AG, Lacroix J, and members of the International Consensus Conference Panel. International Pediatric Sepsis Consensus Conference: Definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 2005; 6: 2-8.

Determinants of red blood cell transfusion in Pediatric Intensive Care Unit: a prospective epidemiologic study - Armano R, Gauvin F, Ducruet T, Lacroix J. Determinants of red blood cell transfusion in Pediatric Intensive Care Unit: a prospective epidemiologic study. Crit Care Med 2005; 33(11): 2637-2644.

Noninvasive therapy with helium-oxygen for severe bronchiolitis - Liet JM, Millotte B, Tucci M, Laflamme S, Hutchison JS, Creery D, Ducruet T, Lacroix J. Noninvasive therapy with helium-oxygen for severe bronchiolitis. J Pediatr 2005; 147(6): 812-817.

Cumulative influence of organ dysfunctions and septic state on mortality of critically ill children - Leclerc F, Leteurtre S, Duhamel A, Grandbastien B, Proulx F, Martinot A, Gauvin F, Hubert P, Lacroix J. Cumulative influence of organ dysfunctions and septic state on mortality of critically ill children. Am J Respir Crit Care Med 2005; 171(4): 348-353.

Reply to Knudsen and Kristiansen - Simon L, Gauvin F, Amre D, St-Louis P, Lacroix J. Reply to Knudsen and Kristiansen. Clin Infect Dis 2005; 40(9): 1373-1374; erratum 1386-1388.

Interactions of sepsis, organ dysfucntion, and outcome of critically in children - Leclerc F, Leteurtre S, Duhamel A, Lacroix J. Interactions of sepsis, organ dysfucntion, and outcome of critically in children. Am J Respir Crit Care Med 2005; 172: 1606-1607.

Red blood cell transfusion practices in pediatric critical care - Lacroix J, Tucci M, Gauvin F. Red blood cell transfusion practices in pediatric critical care. Transfus Altern Transfus Med 2004; 6(2): 22-26.

Grandeurs et misères de la recherche clinique appliquée - Lacroix J. Grandeurs et misères de la recherche clinique appliquée. P.R.I.S.M.E. 2004; 42: 148-152.

Transfusion practices in pediatric critical care - Lacroix J, Tucci M. Transfusion practices in pediatric critical care. Transfus Altern Transfus Med 2004; 6: S59-60.

Transfusion in pediatrics - Desmet VJ, Lacroix J. Transfusion in pediatrics. Crit Care Med 2004; 20(2): 299-311.

Diaphragm electrical activity during synchronized intermittent mandatory ventilation in infants - Beck J, Tucci M, Emeriaud G, Lacroix J, Sinderby C. Diaphragm electrical activity during synchronized intermittent mandatory ventilation in infants. Pediatr Res 2004; 55: 1-8.

Sepse/Sindrome da resposta inflamatoria systêmica (SRIS) (Sepsis and systemic inflammatory syndrome (SIRS)) - Simon L, Farrell CA, Lacroix J, Proulx F, Toledano B, Piva JP, Garcia PCR. Sepse/Sindrome da resposta inflamatoria systêmica (SRIS) (Sepsis and systemic inflammatory syndrome (SIRS)). Dans: Piva JP, Garcia PCR (eds). Medicina intensiva em Pediatra, 5e édition. Rio de Janiero. Editora Medsi, 2004; 103-134.

Serum procalcitonin and C-reactive protein as markers of bacterial infection: A systematic review and meta-analysis - Simon L, Gauvin F, Amre D, St-Louis P, Lacroix J. Serum procalcitonin and C-reactive protein as markers of bacterial infection: A systematic review and meta-analysis. Clin Infect Dis 2004; 39(2): 206-217.

Prolonged neural expiratory time induced by mechanical ventilation in infants - Beck J, Tucci M, Emeriaud G, Lacroix J, Sinderby C. Prolonged neural expiratory time induced by mechanical ventilation in infants. Pediatr Res 2004; 55(5): 747-754.

Bronchiolitis; what next? - Guerguerian A-M, Farrell CA, Gauthier M, Lacroix J. Bronchiolitis; what next?. Pediatr Crit Care Med 2004; 5(5): 498-500.

Prolonged neural expiratory time induced by mechanical ventilation in infants - Beck J, Tucci M, Emeriaud G, Lacroix J, Sinderby C. Prolonged neural expiratory time induced by mechanical ventilation in infants. Pediatr Res 2004; 55(5): 747-754.

Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study - Leteurtre S, Martinot A, Duhamel A, Proulx F, Grandbastien B, Cotting J, Gottesman R, Joffe A, Pfenninger J, Hubert P, Lacroix J, Leclerc F. Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study. Lancet 2003; 362(9379): 192-197.

Erythropoietin for critically ill children - Lacroix J, Toledano B. Erythropoietin for critically ill children. Pediatr Crit Care Med 2003; 4(1): 123-124.

The habit and the hub (éditorial) - Lacroix J, Gauvin F. The habit and the hub (éditorial). Crit Care Med 2003; 31(5): 1583-1584.

Décision de transfusion érythrocytaire en réanimation - Hébert P, Lacroix J. Décision de transfusion érythrocytaire en réanimation. Réanimation 2003; 12: 615-622.

Naloxone for patients in shock (Cochrane Review) - Boeuf B, Poirier V, Gauvin F, Guerguerian A-M, Roy CC, Farrell CA, Lacroix J. Naloxone for patients in shock (Cochrane Review). Dans: The Cochrane Library. Chichester, UK. John Wiley Sons, Ltd, 2003; Issue 4.

The effect of short-term dimethylglycine treatment on oxygen consumption in cytochrome oxidase deficiency: A double-blind randomized crossover trial - Liet JM, Pelletier V, Robinson BH, Laryea MD, Wendel U, Morneau S, Morin C, Mitchell GA, Lacroix J. The effect of short-term dimethylglycine treatment on oxygen consumption in cytochrome oxidase deficiency: A double-blind randomized crossover trial. J Pediatr 2003; 142(1): 62-66.

Evaluation of the pediatric risk of admission (PRISA) score in a pediatric emergency department - Gravel J, Gouin S, Amre D, Bergeron S, Lacroix J. Evaluation of the pediatric risk of admission (PRISA) score in a pediatric emergency department. Ann Emerg Med 2003; 41(5): 630-638.

Ventilator-associated pneumonia in intubated children: comparison of different diagnostic methods - Gauvin F, Dassa C, Chaïbou M, Proulx F, Farrell CA, Lacroix J. Ventilator-associated pneumonia in intubated children: comparison of different diagnostic methods. Pediatr Crit Care Med 2003; 4(4): 437-443.

Randomized clinical trials in pediatric critical care: Rarely done but desperately needed - Randolph AG, Lacroix J. Randomized clinical trials in pediatric critical care: Rarely done but desperately needed. Pediatr Crit Care Med 2002; 3: 102-107.

Book review: Nosocomial infections - Gauvin F, Lacroix J. Book review: Nosocomial infections. Crit Care Med 2002; 30(3): 724-725.

Reproductivity of blind protected bronchoalveolar lavage in mechanically-ventilated children - Gauvin F, Lacroix J, Guertin M-C, Proulx F, Farrell CA, Moghrabi A, Lebel P, Dassa C. Reproductivity of blind protected bronchoalveolar lavage in mechanically-ventilated children. Am J Respir Crit Care Med 2002; 165(12): 1618-1623.

An update on pediatric multiple organ dysfunction syndrome - Armano R, Proulx F, Toledano B, Lacroix J. An update on pediatric multiple organ dysfunction syndrome. Recent Res Dev Resp Crit Care Med 2002; 2: 83-101.

Survey of transfusion practices of pediatric intensive care units - Laverdière C, Gauvin F, Hébert P, Infante-Rivard C, Hume HA, Toledano B, Guertin M-C, Lacroix J, and the Canadian Critical Care Trial Group. Survey of transfusion practices of pediatric intensive care units. Pediatr Crit Care Med 2002; 3(4): 335-340.

Drogues et produits entraînant une dépendance: cannabis, amphétamines, cocaïne, hallucinogènes, PCP et drogues de synthèse - Millotte B, Bailey B, Arditti J, Lacroix J. Drogues et produits entraînant une dépendance: cannabis, amphétamines, cocaïne, hallucinogènes, PCP et drogues de synthèse. Dans: Bedry R, Llanas B, Danel V, Fayon M (eds). Guide pratique de toxicologie pédiatrique, 1ère édition. Bordeaux. Arnette, 2002; 181-190.

Fin de vie en réanimation pédiatrique: expérience canadienne - Millotte B, Farrell CA, Gauvin F, Lacroix J. Fin de vie en réanimation pédiatrique: expérience canadienne. Dans: Dhainault JF (ed). Actualités en Réanimation et Urgences. Paris. Arnette, 2002; 385-392.

Le syndrome de défaillance multiviscérale pédiatrique en salle d'urgence - Armano R, Proulx F, Toledano B, Lacroix J. Le syndrome de défaillance multiviscérale pédiatrique en salle d'urgence. Urgence Pratique 2002; 53: 11-14.

Hyperbaric oxygen for children with cerebral palsy: a randomised multicentre trial - Collet JP, Vanasse M, Marois P, Amar M, Goldberg J, Lambert J, Lassonde M, Hardy P2, Fortin J, Tremblay SD, Montgomery D, Lacroix J, Robinson A, Majnemer A. Hyperbaric oxygen for children with cerebral palsy: a randomised multicentre trial. Lancet 2001; 357(9256): 582-586.

Hyperbaric oxygenation for cerebral palsy (lettre) - Collet JP, Lassonde M, Tremblay S, Lacroix J, Majnemer A. Hyperbaric oxygenation for cerebral palsy (lettre). Lancet 2001; 357: 253.

Pediatric sepsis and multiple organ dysfunction syndrome - Despond O, Proulx F, Carcillo J, Lacroix J. Pediatric sepsis and multiple organ dysfunction syndrome. Curr Opin Pediatr 2001; 13(3): 247-253.

The impact of clinically significant upper gastrointestinal bleeding acquired in a pediatric intensive care unit - Gauvin F, Dugas M-A, Chaïbou M, Morneau S, Lebel D, Lacroix J. The impact of clinically significant upper gastrointestinal bleeding acquired in a pediatric intensive care unit. Pediatr Crit Care Med 2001; 2: 294-298.

La ventilation liquide et la place de la kinésithérapie en réanimation pédiatrique - Lacroix J, Morneau S, Farrell CA. La ventilation liquide et la place de la kinésithérapie en réanimation pédiatrique. Kinéréa 2000; 24: 50-54.

Pulmonary injury after intravenous hydrocarbon (Varsol) injection - Guerguerian A-M, Lacroix J. Pulmonary injury after intravenous hydrocarbon (Varsol) injection. Paediatr Child Health 2000; 5: 471-472.

End-of-life issues in the ICU: A need for acute palliative care? - Rocker G, Shemie S, Lacroix J. End-of-life issues in the ICU: A need for acute palliative care?. J Palliat Care 2000; 16: S5-6.

Markers of tissue hypoperfusion in pediatric septic shock - Dugas M-A, Proulx F, de Jaegger A, Lacroix J, Lambert MA. Markers of tissue hypoperfusion in pediatric septic shock. Intensive Care Med 2000; 26: 75-83.

Reactive hemophagocytic syndrome presenting as a component of multiple dysfunction syndrome - Gauvin F, Toledano B, Champagne J, Lacroix J. Reactive hemophagocytic syndrome presenting as a component of multiple dysfunction syndrome. Crit Care Med 2000; 28(9): 3341-3345.

Hemolytic uremic syndrome associated with invasive streptococcus pneumoniae infection - Proulx F, Liet JM, David M, Seidman EG, Tapiero B, Robitaille P, Lacroix J. Hemolytic uremic syndrome associated with invasive streptococcus pneumoniae infection. Pediatr Res 2000; 105: 462-463.

Hypotensive reaction associated with platelet transfusion through leukocyte reduction filte - Gauvin F, Toledano B, Hume HA, Lacroix J. Hypotensive reaction associated with platelet transfusion through leukocyte reduction filte. J Intensive Care Med 2000; 15: 329-332.

Decision making and end-of-life care in critically ill children: an interpretive review - Masri C, Farrell CA, Lacroix J, Rocker G, Shemie S. Decision making and end-of-life care in critically ill children: an interpretive review. J Palliat Care 2000; 16 (suppl): S45-52.

Pratiques de transfusion de concentré globulaire en réanimation pédiatrique - Gauvin F, Chaïbou M, Leteurtre S, Toledano B, Hume HA, Proulx F, Hébert P, Martinot A, Leclerc F, Lacroix J. Pratiques de transfusion de concentré globulaire en réanimation pédiatrique. Réan Urg 2000; 9: 339-344.

La ventilation artificielle chez l'enfant: les acquis des cinq dernières années (Mechanical ventilation in children: an update) - Lacroix J, Morneau S. La ventilation artificielle chez l'enfant: les acquis des cinq dernières années (Mechanical ventilation in children: an update). Arch Pediatr 1999; 6(2): 496-497.

L'évolution des urgences pédiatriques à l'Hôpital Sainte-Justine - Lacroix J, Arseneault M. L'évolution des urgences pédiatriques à l'Hôpital Sainte-Justine. Arch Pediatr 1999; 6(2): 457-458.

Encéphalite aiguë grave pédiatrique: 14 cas consécutifs - Guerguerian A-M, Tucci M, Toledano B, Farrell CA, Proulx F, Lacroix J. Encéphalite aiguë grave pédiatrique: 14 cas consécutifs. Réan Urg 1999; 8: 395-398.

Development of a pediatric multiple organ dysfunction score. Use of two strategies - Leteurtre S, Martinot A, Duhamel A, Gauvin F, Grandbastien B, Nam TV, Proulx F, Lacroix J. Development of a pediatric multiple organ dysfunction score. Use of two strategies. Med Decis Making 1999; 19: 399-410.

A randomized, double-blind placebo-controlled clinical trial of ribavirin in children mechanically ventilated for a bronchiolitis caused by respiratory syncitial virus - Guerguerian A-M, Gauthier M, Lebel MH, Farrell CA, Lacroix J. A randomized, double-blind placebo-controlled clinical trial of ribavirin in children mechanically ventilated for a bronchiolitis caused by respiratory syncitial virus. Am J Respir Crit Care Med 1999; 160: 829-834.

Protected specimen brush or bronchoalveolar lavage to diagnose bacterial nosocomial pneumonia in ventilated adults: a meta-analysis - de Jaegger A, Litalien C, Lacroix J, Guertin M-C, Infante-Rivard C. Protected specimen brush or bronchoalveolar lavage to diagnose bacterial nosocomial pneumonia in ventilated adults: a meta-analysis. Crit Care Med 1999; 27: 2548-2560.

Stroke-like episodes in autosomal recessive cytochrome oxidase deficiency - Morin C, Dubé J, Robinson BH, Lacroix J, Michaud J, de Braekeller M, Geoffroy G, Lortie A, Blanchette BS, Lambert MA, Mitchell GA. Stroke-like episodes in autosomal recessive cytochrome oxidase deficiency. Ann Neurol 1999; 45(3): 389-392.

Nosocomial infections in the PICU: Epidemiology and control - Lacroix J, Skippen P, Cox P, Langley JM, Matlow A, Barker G, Lee Ford-Jones E. Nosocomial infections in the PICU: Epidemiology and control. Dans: Fuhrman BP, Zimmerman JJ (eds). Pediatric Critical Care, 2e édition. St-Louis. Mosby Year Book, 1998; 1035-1059.

Nosocomial infection: Diagnostic criteria - Lacroix J, Gauvin F. Nosocomial infection: Diagnostic criteria. Dans: Fatima DM, Freire M, Sapolnik R, Araujo K (eds). Actualizaçao em Terapia Intensiva Pediatrica. Salvador. P & A Grafia e Editora Ltd, 1998; 81-101.

Multiple organ dysfunction failure - Lacroix J, Proulx F. Multiple organ dysfunction failure. Dans: Fatima DM, Freire M, Sapolnik R, Araujo K (eds). Actualizaçao em Terapia Intensiva Pediatrica. Salvador. P & A Grafia e Editora Ltd, 1998; 45-62.

Septic shock: Immunomodulation - Lacroix J, Toledano B. Septic shock: Immunomodulation. Dans: Fatima DM, Freire M, Sapolnik R, Araujo K (eds). Actualizaçao em Terapia Intensiva Pediatrica. Salvador. P & A Grafia e Editora Ltd, 1998; 27-44.

The influence of ischemia-reperfusion injury on plasma malondialdehyde undergoing cardiopulmonary bypass - Fayon M, Lacroix J, Champagne J, Lepage G, Chartrand C, Vobecky S, Farrell CA, Delvin EE. The influence of ischemia-reperfusion injury on plasma malondialdehyde undergoing cardiopulmonary bypass. Intensive Care Med 1998; 13(1): 44-52.

Markers of cellular dysoxia during orthotopic liver transplantation in pigs - de Jaegger A, Proulx F, Yandza T, Dugas M-A, Boeuf B, Manika A, Lacroix J, Lambert MA. Markers of cellular dysoxia during orthotopic liver transplantation in pigs. Intensive Care Med 1998; 24: 268-275.

Incidence and risk factors of catherter-related deep vein thrombosis in a Pediatric Intensive Care Unit. A Prospective Study - Beck C, Dubois J, Grignon A, Lacroix J, David M. Incidence and risk factors of catherter-related deep vein thrombosis in a Pediatric Intensive Care Unit. A Prospective Study. J Pediatr 1998; 133: 237-241.

Safety of endotracheal Rh-DNAse for treatment of pulmonary atelectasis in mechanically ventilated children - Boeuf B, Proulx F, Morneau S, Marton D, Lacroix J. Safety of endotracheal Rh-DNAse for treatment of pulmonary atelectasis in mechanically ventilated children. Pediatr Pulmonol 1998; 26: 147.

Clinically significant upper gastrointestinal bleeding acquired in a pediatric intensive care unit: A prospective study - Chaïbou M, Tucci M, Dugas M-A, Farrell CA, Proulx F, Lacroix J. Clinically significant upper gastrointestinal bleeding acquired in a pediatric intensive care unit: A prospective study. Pediatr Res 1998; 102: 933-938.

Maladies obstructives laryngo-tranchéales chroniques ou récidivantes chez l'enfant - Gauvin F, Quintal MC, Farrell CA, Bergeron S, Lacroix J. Maladies obstructives laryngo-tranchéales chroniques ou récidivantes chez l'enfant. Med Ther Ped 1998; 1(5): 419-425.

Le syndrome de défaillance multiviscérale pédiatrique - Proulx F, Dugas M-A, Boeuf B, Lacroix J. Le syndrome de défaillance multiviscérale pédiatrique. Med Ther 1998; 1: 427-433.

Therapy of shock with naloxone: a meta-analysis - Boeuf B, Gauvin F, Guerguerian A-M, Farrell CA, Lacroix J, Jenicek M. Therapy of shock with naloxone: a meta-analysis. Crit Care Med 1998; 26(11): 1910-1916.

Hepatic failure - de Jaegger A, Lacroix J. Hepatic failure. Dans: Singh NC (ed). Manual of pediatric critical care. Philadelphie. Saunders company, 1997; 240-246.

Acquired carnitine abnormalities in critically ill children - Proulx F, Lacroix J, Qureshi IA, Nadeau D, Gauthier M, Lambert MA. Acquired carnitine abnormalities in critically ill children. Eur J Pediatr 1997; 156: 864-869.

Pediatric multiple organ dysfunction syndrome - Proulx F, Boeuf B, Lacroix J. Pediatric multiple organ dysfunction syndrome. Intensive Care Med 1997; 14: 79-82.

Epidemiology of sepsis and multiple organ dysfunction syndrome - Proulx F, Fayon M, Farrell CA, Lacroix J, Gauthier M. Epidemiology of sepsis and multiple organ dysfunction syndrome. Dans: Parillo JE, Balk RA, Calvin JE, Franklin CM, Shapiro BA (eds). Year Book of Critical Care Medicine. St-Louis. Mosby, 1997; 29.

Nosocomial bacterial pneumonia and tracheitis in pediatric intensive care - Fayon M, Tucci M, Lacroix J, Farrell CA, Gauthier M, Lafleur L, Nadeau D. Nosocomial bacterial pneumonia and tracheitis in pediatric intensive care. Am J Respir Crit Care Med 1997; 155: 162-169.

Problèmes d'électrolytes en pédiatrie - Toledano B, Tucci M, Lacroix J, Farrell CA. Problèmes d'électrolytes en pédiatrie. Dans: Offenstadt G, Brunette MG (eds). Désordres acido-basiques et hydro-électrolythiques. Paris. Arnette, 1997; 407-443.

Innocuité de la Rh DNase (Pulmozyme tm) dans le traitement des atélectasies pulmonaires chez l'enfant ventilé mécaniquement - Proulx F, Morneau S, Marton D, Lacroix J. Innocuité de la Rh DNase (Pulmozyme tm) dans le traitement des atélectasies pulmonaires chez l'enfant ventilé mécaniquement. Réan Urg 1997; 6(6): 709-829.

Blood lactate and gastric intramucosal pH during severe sepsis - Proulx F, Lacroix J, Farrell CA, Gauthier M, Lambert MA. Blood lactate and gastric intramucosal pH during severe sepsis. Crit Care Med 1996; 24: 1092.

Epidemiology of sepsis and multiple organ dysfunction syndrome - Proulx F, Fayon M, Farrell CA, Lacroix J, Gauthier M. Epidemiology of sepsis and multiple organ dysfunction syndrome. Chest 1996; 109: 1033-1037.

The clinical and economic consequences of clinically ill gastrointestinal bleeding in critically ill patients - Heyland D, Gafni A, Griffith L, Cook D, Fuller H, Marshall J, Todd T, Guslits B, Heule M, Hewson J, Lacroix J, Noseworthy T, and the Canadian Critical Care Trial Group, Powles P. The clinical and economic consequences of clinically ill gastrointestinal bleeding in critically ill patients. Clin Intens Care 1996; 7: 121-125.

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