Chercheur

    Sylvana Côté , Ph.D.

    sylvana.cote.1@umontreal.ca
    Sylvana Côté
    Axe de recherche
    Cerveau et développement de l’enfant
    Thème de recherche
    Développement des psychopathologies

    Téléphone
    514 343-6963

    Fax
    514 343-6962

    Sur le Web

    Titres

    • Professeure agrégée, Médecine Sociale et Préventive, Université de Montréal

    Formation

    • Postdoctorat, Heinz School of Public Policy, Carnegie Mellon, États-Unis, 2001-2003
    • PhD en psychologie, Université de Montréal, 1997-2001
    • Maîtrise en psychologie, Université Laval, 1994-1996
    • Baccalauréat en psychologie, Université McGill 1991-1994

    Intérêts de recherche

    Mes travaux examinent les domaines de la psychopathologie développementale et de l’épidémiologie de la santé mentale au cours de la vie. Mon programme de recherche est centré sur l’étude de la transmission intergénérationnelle des facteurs de risque pour les problèmes de santé mentale et l’efficacité de la prévention de ces problèmes par des services périnataux et préscolaires. Mon programme de recherche comprend deux axes de recherche et un axe de transfert de connaissances :

    A) l’axe étiologie ayant pour objectif l’étude des mécanismes bio-psycho-sociaux de transmission intergénérationnelle des problèmes de santé mentale;

    B) l’axe prévention ayant pour objectif l’identification des services périnataux et préscolaires qui sont les plus efficaces dans la prévention des problèmes de santé mentale;

    C) l’axe transfert de connaissance ayant pour objectif de diffuser les connaissances concernant les services périnataux et préscolaires les plus efficaces afin d’améliorer ces services.

    Prix et distinctions

    • Chercheure Sénior, Fond de Recherche en Santé du Québec (FRSQ), 2011-2016
    • Nouveau chercheur, Instituts de recherche en santé du Canada (IRSC), 2006-2011
    • Chaire de recherche Belle van Zuylen, Université d’Utrecht, Pays-Bas, 2006
    • Prix Mary C. Early, Fondation canadienne de la recherche psychiatrique, 2005
    • Bourse postdoctorale, Conseil de recherches en sciences humaines du Canada (CRSH), 2001-2003
    • Bourse doctorale, Conseil de recherche en sciences humaines du Canada (CRSH), 1998-2001
    • Bourse doctorale, National Consortium on Violence Research (NCOVR), National Science Foundation (NSF), 1999-2001
    • Prix McConnell/SSHRC récompensant l'excellence dans la diffusion de la recherche, 1999

Publications

DNA methylation signature of childhood chronic physical aggression in T cells of both men and women - Guillemin C, Provençal N, Suderman MJ, Côté S, Vitaro F, Hallett M, Tremblay RE, Szyf M. DNA methylation signature of childhood chronic physical aggression in T cells of both men and women. PLoS ONE 2014; 9(1): e86822.

Association of childhood chronic physical aggression with a DNA methylation signature in adult human T cells - Provençal N, Suderman MJ, Guillemin C, Vitaro F, Côté S, Hallett M, Tremblay RE, Szyf M. Association of childhood chronic physical aggression with a DNA methylation signature in adult human T cells. PLoS ONE 2014; 9(4): e89839.

Child care in infancy and cognitive performance until middle childhood in the Millennium cohort study - Côté S, Doyle O, Petitclerc A, Timmins L. Child care in infancy and cognitive performance until middle childhood in the Millennium cohort study. Child Development 2013; 84(4): 1191-1208.

Child care quality and cognitive development: trajectories leading to better preacademic skills - Côté S, Mongeau C, Japel C, Xu Q, Séguin JR, Tremblay RE. Child care quality and cognitive development: trajectories leading to better preacademic skills. Child Development 2013; 84(2): 752-766.

Childhood trajectories of inattention, hyperactivity and oppositional behaviors and prediction of substance abuse/dependence: a 15-year longitudinal population-based study - Pingault J-B, Côté S, Galéra C, Genolini C, Falissard B, Vitaro F, Tremblay RE. Childhood trajectories of inattention, hyperactivity and oppositional behaviors and prediction of substance abuse/dependence: a 15-year longitudinal population-based study. Mol Psychiatry 2013; 18(7): 806-812.

Age-dependent effect of the MAOA gene on childhood physical aggression - Pingault J-B, Côté S, Booij L, Ouellet-Morin I, Castellanos-Ryan N, Vitaro F, Turecki G, Tremblay RE. Age-dependent effect of the MAOA gene on childhood physical aggression. Mol Psychiatry 2013; 18(11): 1151-1152.

Childhood hyperactivity, physical aggression and criminality: a 19-year prospective population-based study - Pingault J-B, Côté S, Lacourse E, Galéra C, Vitaro F, Tremblay RE. Childhood hyperactivity, physical aggression and criminality: a 19-year prospective population-based study. PLoS ONE 2013; 8(5): e62594.

Maternal depressive symptoms and children's emotional problems: can early child care help children of depressed mothers? - Herba C, Tremblay RE, Boivin M, Liu X, Mongeau C, Séguin JR, Côté S. Maternal depressive symptoms and children's emotional problems: can early child care help children of depressed mothers?. JAMA 2013; 70(8): 830-838.

Childcare and overweight or obesity over 10 years of follow-up - Geoffroy MC, Power C, Touchette É, Dubois L, Boivin M, Séguin JR, Tremblay RE, Côté S. Childcare and overweight or obesity over 10 years of follow-up. J Pediatr 2013; 162(4): 753-758.e1.

KmL3D: A non-parametric algorithm for clustering joint trajectories - Genolini C, Pingault J-B, Driss T, Côté S, Tremblay RE, Vitaro F, Arnaud C, Falissard B. KmL3D: A non-parametric algorithm for clustering joint trajectories. Comput Meth Prog Bio 2013; 109(1): 104-111.

Smoking and medication during pregnancy predict repeated unintentional injuries in early childhood - Junger M, Japel C, Xu Q, Côté S, Boivin M, Tremblay RE. Smoking and medication during pregnancy predict repeated unintentional injuries in early childhood. Prev Sci 2013; 14(1): 13-24.

Cohort profile: the Quebec longitudinal study of kindergarten children (QLSKC) - Rouquette A, Côté S, Pryor L, Carbonneau R, Vitaro F, Tremblay RE. Cohort profile: the Quebec longitudinal study of kindergarten children (QLSKC). Int J Epidemiol 2012; (sous presse).

Parental characteristics associated with childcare use during the first 4 years of life: Results from a representative cohort of Québec families - Geoffroy MC, Séguin JR, Lacourse E, Boivin M, Tremblay RE, Côté S. Parental characteristics associated with childcare use during the first 4 years of life: Results from a representative cohort of Québec families. Can J Public Health 2012; 103(1): 76-80.

Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression - Wang D, Szyf M, Benkelfat C, Provençal N, Turecki G, Caramaschi D, Côté S, Vitaro F, Tremblay RE, Booij L. Peripheral SLC6A4 DNA methylation is associated with in vivo measures of human brain serotonin synthesis and childhood physical aggression. PLoS ONE 2012; 7(6): e39501.

The signature of maternal rearing in the methylome in Rhesus Macaque prefrontal cortex and T cells - Provençal N, Suderman MJ, Guillemin C, Massart R, Ruggiero A, Wang D, Bennett AJ, Pierre PJ, Friedman D, Côté S, Hallett M, Tremblay RE, Suomi SJ, Szyf M. The signature of maternal rearing in the methylome in Rhesus Macaque prefrontal cortex and T cells. J Neurosci 2012; 32(44): 15626-15642.

A new approach of personality and psychiatric disorders: a short version of the Affective Neuroscience Personality Scales - Pingault J-B, Falissard B, Côté S, Berthoz S. A new approach of personality and psychiatric disorders: a short version of the Affective Neuroscience Personality Scales. PLoS ONE 2012; 7(7): e41489.

Moderating effects of team sports participation on the link between victimization and mental heatlh problems - Perron A, Brendgen M, Vitaro F, Côté S, Tremblay RE, Boivin M. Moderating effects of team sports participation on the link between victimization and mental heatlh problems. Mental Health Phys Activities 2012; (sous presse).

Does sports protect victimized children from depressive symptoms and externalizing problems? - Perron A, Brendgen M, Vitaro F, Côté S, Tremblay RE, Boivin M. Does sports protect victimized children from depressive symptoms and externalizing problems?. J Abnorm Child Psychol 2012; (sous presse).

Childhood trajectories of inattention and hyperactivity and prediction of educational attainment in early adulthood: a 16-year longitudinal population-based study - Pingault J-B, Tremblay RE, Vitaro F, Carbonneau R, Genolini C, Falissard B, Côté S. Childhood trajectories of inattention and hyperactivity and prediction of educational attainment in early adulthood: a 16-year longitudinal population-based study. Am J Psychiatry 2011; 168(11): 1164-1170.

Early risk factors for hyperactivity-impulsivity and inattention trajectories from age 17 months to 8 years - Galéra C, Côté S, Bouvard MP, Pingault J-B, Melchior M, Michel G, Boivin M, Tremblay RE. Early risk factors for hyperactivity-impulsivity and inattention trajectories from age 17 months to 8 years. Arch Gen Psychiatry 2011; 68(12): 1267-1275.

Developmental trajectories of body mass index in early childhood and their risk factors: an 8-year longitudinal study - Pryor L, Tremblay RE, Boivin M, Touchette É, Dubois L, Genolini C, Liu X, Falissard B, Côté S. Developmental trajectories of body mass index in early childhood and their risk factors: an 8-year longitudinal study. Arch Pediat Adol Med 2011; 165(10): 906-912.

Subclinical eating disorders and their comorbidity with mood and anxiety disorders in adolescent girls - Touchette É, Henegar A, Godart NT, Pryor L, Falissard B, Tremblay RE, Côté S. Subclinical eating disorders and their comorbidity with mood and anxiety disorders in adolescent girls. Psychiat Res 2011; 185(1-2): 185-192.

Linking developmental propensity score to fuzzy sets: a new perspective, applications and generalizations - Liu X, Côté S, Tremblay RE, Carbonneau R. Linking developmental propensity score to fuzzy sets: a new perspective, applications and generalizations. Dans: Li S, Wang X, Okazaki Y, Kawabe J, Murofushi T, Guan L (eds). Nonlinear Mathematics for Uncertainty and its Applications (Advances in Intelligent and Soft Computing). Springer, 2011; 341-348.

Prenatal alcohol exposure and cortisol activity in 19-month-old toddlers: an investigation of the moderating effects of sex and testosterone - Ouellet-Morin I, Dionne G, Lupien S, Muckle G, Côté S, Pérusse D, Tremblay RE, Boivin M. Prenatal alcohol exposure and cortisol activity in 19-month-old toddlers: an investigation of the moderating effects of sex and testosterone. Psychopharmacology 2011; 214(1): 297-307.

Linking developmental propensity scores to fuzzy sets: A new perspective, applications and generalizations - Liu X, Tremblay RE, Côté S, Carbonneau R. Linking developmental propensity scores to fuzzy sets: A new perspective, applications and generalizations. Int J Intelligent Technol and Applied Stat 2011; 4(4): 419-430.

Short- and long-term risk for infections as a function of group child care attendance: an 8-year-population-based study - Côté S, Petitclerc A, Raynault M-F, Xu Q, Falissard B, Boivin M, Tremblay RE. Short- and long-term risk for infections as a function of group child care attendance: an 8-year-population-based study. Arch Pediat Adol Med 2010; 164(12): 1132-1137.

Pre-school education services and aggressive behavior: a preventive role in vulnerable families - Côté S, Pingault J-B, Boivin M, Japel C, Nagin D, Xu Q, Zoccolillo M, Junger M, Tremblay RE. Pre-school education services and aggressive behavior: a preventive role in vulnerable families . Psychiatry Science Human Neurosciences 2010; 8: 77-87.

Closing the gap in academic readiness and achievement: the role of early childcare - Geoffroy MC, Côté S, Giguère C, Dionne G, Zelazo PD, Tremblay RE, Boivin M, Séguin JR. Closing the gap in academic readiness and achievement: the role of early childcare. J Child Psychol Psychiatry 2010; 51(12): 1359-1367.

Diurnal cortisol secretion at home and in child care: a prospective study of 2-year-old toddlers - Ouellet-Morin I, Tremblay RE, Boivin M, Meaney M, Kramer M, Côté S. Diurnal cortisol secretion at home and in child care: a prospective study of 2-year-old toddlers. J Child Psychol Psychiatry 2010; 51(3): 295-303.

Depression and anxiety symptoms: onset, developmental course and risk factors during early childhood - Côté S, Boivin M, Liu X, Nagin D, Zoccolillo M, Tremblay RE. Depression and anxiety symptoms: onset, developmental course and risk factors during early childhood. J Child Psychol Psychiatry 2009; 50(10): 1201-1208.

Sex differences in types of aggressive behaviours: Do women have a higher level of conscience than men? - Côté S. Sex differences in types of aggressive behaviours: Do women have a higher level of conscience than men? . Dans: Koops K, Brugman D, Ferguson TJ, Sanders AF (eds). The Development and Structure of Conscience. New York (NY). Psychology Press, 2009; 287-310.

A developmental perspective on sex differences in aggressive behaviours - Côté S. A developmental perspective on sex differences in aggressive behaviours. Dans: Tremblay RE, Van Aken M (eds). The development of behavior problems. New York (NY). Psychology Press, 2009; 143-163.

Short nighttime sleep-duration and hyperactivity trajectories in early childhood - Touchette É, Côté S, Petit D, Liu X, Falissard B, Boivin M, Tremblay RE, Montplaisir J. Short nighttime sleep-duration and hyperactivity trajectories in early childhood. Pediatrics 2009; 124(5): e985-993.

Development of sex differences in physical aggression: the maternal link to epigenetic mechanisms - Tremblay RE, Côté S. Development of sex differences in physical aggression: the maternal link to epigenetic mechanisms. Behav Brain Sciences 2009; 32(3-4): 290-291; discussion 292-311.

La garderie avant 2 ans nuisible pour les enfants: Mythe ou réalité? - Geoffroy MC, Manningham S, Séguin JR, Côté S. La garderie avant 2 ans nuisible pour les enfants: Mythe ou réalité?. Revue de psychoéducation 2009; 38: 111-115.

Policy implications of present knowledge on the development and prevention of physical aggression and violence - Junger M, Feder L, Côté S, Tremblay RE. Policy implications of present knowledge on the development and prevention of physical aggression and violence. Dans: Tremblay RE, Van Aken MAG, Koops W (eds). Development and prevention of behaviour problems: From genes to social policy. New York (NY). Psychology Press, 2009; 181-215.

Prosocial development from childhood to adolescence: A multi-informant perspective with Canadian and Italian longitudinal studies - Nantel-Vivier A, Caprara GV, Tremblay RE, Vitaro F, Kokko K, Pastorelli R, Paciello M, Gerbino M, Côté S. Prosocial development from childhood to adolescence: A multi-informant perspective with Canadian and Italian longitudinal studies. J Child Psychol Psychiatry 2009; 50(5): 590-598.

Nonmaternal care in infancy and emotional/behavioral difficulties at 4 years old: Moderation by family risk characteristics - Côté S, Borge AI, Rutter M, Geoffroy MC, Tremblay RE. Nonmaternal care in infancy and emotional/behavioral difficulties at 4 years old: Moderation by family risk characteristics. Dev Psychol 2008; 44(1): 155-168.

Links between life course trajectories of family dysfunction and anxiety during middle childhood - Pagani L, Japel C, Vaillancourt T, Côté S, Tremblay RE. Links between life course trajectories of family dysfunction and anxiety during middle childhood. J Am Acad Child Adolesc Psychiatry 2008; 36(1): 41-53.

Girls' hyperactivity and physical aggression during childhood predict adjustment problems in early adulthood: a 15-year longitudinal study - Fontaine N, Carbonneau R, Barker ED, Vitaro F, Hébert M, Côté S, Nagin D, Zoccolillo M, Tremblay RE. Girls' hyperactivity and physical aggression during childhood predict adjustment problems in early adulthood: a 15-year longitudinal study. Arch Gen Psychiatry 2008; 65(3): 320-328.

Controlling parenting and chronic physical aggression during elementary school - Joussemet M, Vitaro F, Barker ED, Côté S, Nagin D, Zoccolillo M, Tremblay RE. Controlling parenting and chronic physical aggression during elementary school. Child Development 2008; 79(2): 411-425.

The role of maternal education and non-maternal care services in the prevention of children's physical aggression - Côté S, Boivin M, Nagin D, Japel C, Xu Q, Zoccolillo M, Tremblay RE. The role of maternal education and non-maternal care services in the prevention of children's physical aggression. Arch Gen Psychiatry 2007; 64(11): 1305-1312.

The joint development of physical and indirect aggression: Predictors of continuity and change during childhood - Côté S, Vaillancourt T, Barker ED, Nagin D, Tremblay RE. The joint development of physical and indirect aggression: Predictors of continuity and change during childhood. Dev Psychol 2007; 19(1): 37-55.

Sex differences in physical and indirect aggression: a developmental perspective - Côté S. Sex differences in physical and indirect aggression: a developmental perspective. Eur J Crimin Policy & Research 2007; 13(3-4): XX.

Association between nonmaternal care in the first year of life and children's receptive language skills prior to school entry: the moderating role of socioeconomic status - Geoffroy MC, Côté S, Borge AI, Larouche F, Séguin JR, Rutter M. Association between nonmaternal care in the first year of life and children's receptive language skills prior to school entry: the moderating role of socioeconomic status. J Child Psychol Psychiatry 2007; 48(5): 490-497.

Trajectories and predictors of indirect aggression: results from a nationally representative longitudinal study of Canadian children aged 2-10 - Vaillancourt T, Miller J, Fagbemi J, Côté S, Tremblay RE. Trajectories and predictors of indirect aggression: results from a nationally representative longitudinal study of Canadian children aged 2-10. Aggressive Behav 2007; 33(4): 314-326.

Preventing violence in seven countries: Global convergence in policies - Junger M, Feder L, Clay J, Côté S, Farrington DP, Freiber K, Genovès VG, Homel R, Lösel F, Manning M, Mazerolle P, Santos R, Schmucker M, Sullivan C, Sutton C, van Yperen T, Tremblay RE. Preventing violence in seven countries: Global convergence in policies. Eur J Crimin Policy & Research 2007; 13(3-4): 327-356.

Policy implications of present knowledge on the development and prevention of physical aggression - Junger M, Feder L, Côté S. Policy implications of present knowledge on the development and prevention of physical aggression. Eur J Crimin Policy & Research 2007; 13(3-4): 301-326.

Assocation entre facteurs de risque maternel et l'agressité physique chez les jeunes enfants - Salvas MC, Geoffroy MC, Vitaro F, Boivin M, Tremblay RE, Côté S. Assocation entre facteurs de risque maternel et l'agressité physique chez les jeunes enfants. Devenir 2007; 19(4): 313-325.

Gender differences in physical aggression: a prospective population-based survey of children before and after two years of age - Baillargeon RH, Zoccolillo M, Keenan K, Côté S, Pérusse D, Wu H-X, Boivin M, Tremblay RE. Gender differences in physical aggression: a prospective population-based survey of children before and after two years of age. Dev Psychol 2007; 43(1): 13-26.

The development of physical aggression from toddlerhood to pre-adolescence: a nation wide longitudinal study of Canadian children - Côté S, Vaillancourt T, LeBlanc J-C, Nagin D, Tremblay RE. The development of physical aggression from toddlerhood to pre-adolescence: a nation wide longitudinal study of Canadian children. J Abnorm Child Psychol 2006; 34(1): 71-85.

Daycare attendance, stress, and mental health - Geoffroy MC, Côté S, Séguin JR, Parent S. Daycare attendance, stress, and mental health. Can J Psychiatry 2006; 51(9): 607-615.

Middle chilhood life-course trajectories: Links between family dysfunction and children's behavioral development - Pagani L, Japel C, Girard A, Farhat A, Côté S, Tremblay RE. Middle chilhood life-course trajectories: Links between family dysfunction and children's behavioral development. Dans: Huston AC, Ripke MN (eds). Developmental contexts in middle childhood . New York. Cambridge University Press, 2006; 130-149.

Prediction of early onset deviant peer group affiliation: a 12-year longitudinal study - Lacourse E, Nagin D, Vitaro F, Côté S, Arsenault L, Tremblay RE. Prediction of early onset deviant peer group affiliation: a 12-year longitudinal study. Arch Gen Psychiatry 2006; 63(5): 562-568.

Development and prediction of hyperactive symptoms from 2 to 7 years in a population-based sample - Romano E, Tremblay RE, Faraht A, Côté S. Development and prediction of hyperactive symptoms from 2 to 7 years in a population-based sample. Pediatrics 2006; 117(6): 2101-2010.

Trouble des conduites chez l'enfant et l'adolescent - Cohen-Salmon C, Côté S, Fourneret P, Gasquet I, Guedeney A, Hamon M, Lamboy B, Le Heuzey M-F, Michel G, Reneric J-P, Tremblay RE, Wohl M, Blatier C, Born M, Choquet M, e. Trouble des conduites chez l'enfant et l'adolescent. , 2005; 428 pages.

The developmental origins of aggression: where are we going? - Tremblay RE, Côté S. The developmental origins of aggression: where are we going?. Dans: Tremblay RE, Hartup WH, Archer J (eds). Developmental origins of aggression. New York. Guilford Press, 2005; 447-464.

Sex differences in aggressive behavior: A developmental and evolutionary perspective - Archer J, Côté S. Sex differences in aggressive behavior: A developmental and evolutionary perspective. Dans: Tremblay RE, Hartup WH, Archer J (eds). Developmental origins of aggression. New York. Guilford Press, 2005; 425-446.

The intergenerational transmission of aggression and antisocial behavior - Zoccolillo M, Romano E, Joubert D, Mazzarello T, Côté S, Boivin M, Pérusse D, Tremblay RE. The intergenerational transmission of aggression and antisocial behavior. Dans: Tremblay RE, Hartup WH, Archer J (eds). Developmental origins of aggression. New York. Guilford Press, 2005; 353-375.

La qualité des services à la petite enfance: Résultats de l'étude longitudinale sur le développement des enfants du Québec (ELDEQ) - Japel C, Tremblay RE, Côté S. La qualité des services à la petite enfance: Résultats de l'étude longitudinale sur le développement des enfants du Québec (ELDEQ). Éducation et francophonie 2005; 23(2): 7-27.

Parenting as an important outcome of conduct disorder in girls - Zoccolillo M, Paquette D, Azar R, Côté S, Tremblay RE. Parenting as an important outcome of conduct disorder in girls. Dans: Putallaz M, Bierman KL (eds). Aggression, antisocial behavior and violence among girls: A developmental perspective. New York. Guilford Press, 2004; 241-246.

Early childcare and physical aggression: Differentiating social selection and social causation - Borge AI, Rutter M, Côté S, Tremblay RE. Early childcare and physical aggression: Differentiating social selection and social causation. J Child Psychol Psychiatry 2004; 45(2): 367-376.

Le développement de l'aggression physique au cours de l'enfance: différences entre les sexes et facteurs de risque familiaux - Côté S, Tremblay RE, Vitaro F. Le développement de l'aggression physique au cours de l'enfance: différences entre les sexes et facteurs de risque familiaux. Sociologie et Sociétés 2003; 35(1): 203-220.

The development of impulsivity, fearfulness, and helpfulness during childhood: patterns of consistency and change in the trajectories of boys and girls - Côté S, Tremblay RE, Nagin D, Zoccolillo M, Vitaro F. The development of impulsivity, fearfulness, and helpfulness during childhood: patterns of consistency and change in the trajectories of boys and girls. J Child Psychol Psychiatry 2002; 43(5): 609-618.

Childhood behavioral profiles leading to adolescent conduct disorder: risk trajectories for boys and girls - Côté S, Tremblay RE, Nagin D, Zoccolillo M, Vitaro F. Childhood behavioral profiles leading to adolescent conduct disorder: risk trajectories for boys and girls. J Am Acad Child Adolesc Psychiatry 2002; 41(9): 1086-1094.

A longitudinal-experimental approach to testing theories of antisocial behavior development - Lacourse E, Côté S, Nagin D, Vitaro F, Brendgen M, Tremblay RE. A longitudinal-experimental approach to testing theories of antisocial behavior development. Dev Psychopathol 2002; 14(4): 909-924.

Predicting girls' conduct disorder in adolescence from childhood trajectories of disruptive behaviors - Côté S, Zoccolillo M, Tremblay RE, Nagin D, Vitaro F. Predicting girls' conduct disorder in adolescence from childhood trajectories of disruptive behaviors. J Am Acad Child Adolesc Psychiatry 2001; 40(6): 678-684.

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