Chercheur

    William Fraser , M.D.

    william.fraser@umontreal.ca
    William Fraser
    Axe de recherche
    Pathologies fœtomaternelles et néonatales
    Thème de recherche
    Grossesses à risque
    Adresse
    CHUSJ - Centre de Recherche

    Téléphone
    514 345-4931 #4948

    Fax
    514 345-2195

    Sommaire de carrière

    Utilisation de modèles épidémiologiques dans le but d'évaluer les causes de certaines maladies périnatales telles que les naissances prématurées et l'hypertension gestationnelle. Les diverses études cliniques menées par le Dr Fraser permettent d'évaluer les méthodes thérapeutiques couramment utilisées et cherchent à en développer de plus efficaces au besoin. Le but général de la recherche est de réduire la morbidité ainsi que la mortalité maternelles et néonatales. Dr Fraser favorise également la formation de jeunes chercheurs par le biais d'une initiative stratégique visant à promouvoir l'excellence et l'interdisciplinarité en recherche en santé de la reproduction.

    Pour plus de détails concernant les études du Dr Fraser, aller à la section recherche clinique du site web (MIREC, IRNPQEO, etc.).
     

Publications

Circulating docosahexaenoic acid levels are associated with fetal insulin sensitivity - Zhao JP, Levy E, Fraser W, Julien P, Delvin EE, Montoudis A, Spahis S, Garofalo C, Nuyt A-M, Luo ZC. Circulating docosahexaenoic acid levels are associated with fetal insulin sensitivity. PLoS ONE 2014; 9(1): e85054.

Plasma cotinine indicates an increased risk of preeclampsia in previous and passive smokers - Luo ZC, Julien P, Wei SQ, Audibert F, Smith GN, Fraser W, MIROS study group. Plasma cotinine indicates an increased risk of preeclampsia in previous and passive smokers. Am J Obstet Gynecol 2014; 210(3): 232.e1-5.

Cohort profile: the maternal-infant research on environmental chemicals research platform - Arbuckle TE, Fraser W, Fisher M, Davis K, Liang CL, Lupien N, Bastien S, Velez MP, von Dadelszen P, Hemming DG, Wang J, Helewa ME, Taback S, Sermer M, Foster W, Ross G, Fredette P, Smith G, Walker M, Shear R, Dodds L, Ettinger AS, Weber JP, D'Amour M, Legrand M, Kumarathasan P, Vincent R, Luo ZC, Platt RW, Mitchell GA, Hidiroglou N, Cockell K, Villeneuve M, Rawn DF, Dabeka R, Cao XL, Becalski A, Ratnayake N, Bondy G, Jin X, Wang Z, Tittlemier S, Julien P, Avard D, Weiler H, Leblanc A, Muckle G, Boivin M, Dionne G, Ayotte P, Lanphear B, Séguin JR, Saint-Amour D, Dewailly E, Monnier P, Koren G, Ouellet E. Cohort profile: the maternal-infant research on environmental chemicals research platform. Am J Perinatol 2013; 27(4): 415-425.

Psychosocial stress in pregnancy and preterm birth: associations and mechanisms - Shapiro G, Fraser W, Frasch M, Séguin JR. Psychosocial stress in pregnancy and preterm birth: associations and mechanisms. J Perinat Med 2013; 41(6): 631-645.

What is sufficient evidence to justify a multicenter phase 3 randomized controlled trial in obstetrics? - Constantin G, Shapiro G, Chaillet N, Fraser W. What is sufficient evidence to justify a multicenter phase 3 randomized controlled trial in obstetrics?. Dans: Mattison DR (ed.). Clinical pharmacology during pregnancy. San Diego. Academic Press/Elsevier, 2013; 89-102.

Endothelial nitric oxide synthase gene polymorphisms and risk of preeclampsia - Qi HP, Fraser W, Luo ZC, Julien P, Audibert F, Wei SQ. Endothelial nitric oxide synthase gene polymorphisms and risk of preeclampsia. Am J Perinatol 2013; 30(10): 795-804.

Maternal vitamin D status and adverse pregnancy outcomes: a systematic review and meta-analysis - Wei SQ, Qi HP, Luo ZC, Fraser W. Maternal vitamin D status and adverse pregnancy outcomes: a systematic review and meta-analysis. J Matern Fetal Neonatal Med 2013; 26(9): 889-899.

Early amniotomy and early oxytocin for prevention of, or therapy for, delay in first stage spontaneous labour compared with routine care - Wei SQ, Wo BL, Qi HP, Xu H, Luo ZC, Roy C, Fraser W. Early amniotomy and early oxytocin for prevention of, or therapy for, delay in first stage spontaneous labour compared with routine care. Cochrane DB Syst Rev 2013; 8: CD006794.

Repeated measures of placental growth factor, placental protein 13, and A disintegrin and metalloprotease 12 at first and second trimesters for preeclampsia screening - Boucoiran I, Suarthana E, Rey E, Delvin EE, Fraser W, Audibert F. Repeated measures of placental growth factor, placental protein 13, and A disintegrin and metalloprotease 12 at first and second trimesters for preeclampsia screening. Am J Perinatol 2013; 30(8): 681-688.

Maternal plasma 25-hydroxyvitamin D levels, angiogenic factors, and preeclampsia - Wei SQ, Audibert F, Luo ZC, Nuyt A-M, Mâsse B, Julien P, Fraser W, The MIROS Study Group. Maternal plasma 25-hydroxyvitamin D levels, angiogenic factors, and preeclampsia. Am J Obstet Gynecol 2013; 208(5): 390.e1-6.

Endostatin levels and the risk of subsequent preeclampsia - Thissier-Levy S, Boucoiran I, Luo ZC, Nuyt A-M, Julien P, Fraser W, Audibert F. Endostatin levels and the risk of subsequent preeclampsia. Eur J Obstet Gynecol Reprod Biol 2013; 170(2): 396-400.

Understanding childbirth practices as an organizational cultural phenomenon: a conceptual framework - Behruzi R, Hatem M, Goulet L, Fraser W, Misago C. Understanding childbirth practices as an organizational cultural phenomenon: a conceptual framework. BMC Pregnancy and Childbirth 2013; 13: 205. doi: 10.1186/1471-2393-13-205.

Maternal and fetal leptin, adiponectin levels and associations with fetal insulin sensitivity - Luo ZC, Nuyt A-M, Delvin EE, Fraser W, Julien P, Audibert F, Girard I, Shatenstein B, Deal C, Grenier E, Garofalo C, Levy E. Maternal and fetal leptin, adiponectin levels and associations with fetal insulin sensitivity. Obesity 2013; 21(1): 210-216.

Risks for preeclampsia and small for gestational age: predictive values of placental growth factor, soluble fms-like tyrosine kinase-1, and Inhibin A in singleton and multiple-gestation pregnancies - Boucoiran I, Thissier-Levy S, Wu Y, Wei SQ, Luo ZC, Delvin EE, Fraser W, Audibert F, The MIROS Study Group. Risks for preeclampsia and small for gestational age: predictive values of placental growth factor, soluble fms-like tyrosine kinase-1, and Inhibin A in singleton and multiple-gestation pregnancies. Am J Perinatol 2013; 30(7): 607-612.

Labor and delivery - Fraser W, McMaster RM, Wei S. Labor and delivery. Dans: Goldman MB, Troisi R, Rexrode KM (eds). Women & Health, 2nd edition. Elsevier, 2012; (sous presse).

The components of humanized birth care that bring satisfaction to women in a tertiary hospital - Behruzi R, Hatem M, Goulet L, Fraser W. The components of humanized birth care that bring satisfaction to women in a tertiary hospital. Dans: Altamirano Frias T, Jaquez Cano M (eds). Pregnancy: Risk Factors, Management and Recovery. Nova Publishers, 2012; 185-204.

Vitamin D supplementation for the prevention of pre-eclampsia? ‘First do no harm’ - Wei S, Fraser W. Vitamin D supplementation for the prevention of pre-eclampsia? ‘First do no harm’. BJOG 2012; 119(11): 1417–1418.

Longitudinal vitamin D status in pregnancy and the risk of pre-eclampsia - Wei SQ, Audibert F, Hidiroglou N, Sarafin K, Julien P, Wu Y, Luo ZC, Fraser W. Longitudinal vitamin D status in pregnancy and the risk of pre-eclampsia. BJOG 2012; 119(7): 832-839.

Emerging risk factors for postpartum depression: serotonin transporter genotype and omega-3 fatty acid status - Shapiro G, Fraser W, Séguin JR. Emerging risk factors for postpartum depression: serotonin transporter genotype and omega-3 fatty acid status. Can J Psychiatry 2012; 57(11): 704-712.

Longitudinal vitamin D status in pregnancy and the risk of pre-eclampsia - Wei S, Audibert F, Hidiroglou N, Sarafin K, Julien P, Wu Y, Luo ZC, Fraser W. Longitudinal vitamin D status in pregnancy and the risk of pre-eclampsia. BJOG 2012; 119(7): 832-839.

Organochlorine pollutants and female fertility: a systematic review focusing on in vitro fertilization studies - Kadhel P, Monnier P, Boucoiran I, Chaillet N, Fraser W. Organochlorine pollutants and female fertility: a systematic review focusing on in vitro fertilization studies. Reprod Sci 2012; 19(12): 1246-1259.

Maternal and fetal IGF-I and IGF-II levels, fetal growth, and gestational diabetes - Luo ZC, Nuyt A-M, Delvin EE, Audibert F, Girard I, Shatenstein B, Cloutier A, Cousineau J, Djemli A, Deal C, Levy E, Wu Y, Julien P, Fraser W. Maternal and fetal IGF-I and IGF-II levels, fetal growth, and gestational diabetes. J Clin Endocrinol Metab 2012; 97(5): 1720-1728.

Birth outcomes and infant mortality among First Nations Inuit, and non-Indigenous women by northern versus southern residence, Quebec - Luo ZC, Wilkins R, Heaman M, Smylie J, Martens P, McHugh NG, Labranche E, Simonet F, Wassimi S, Minich K, Fraser W. Birth outcomes and infant mortality among First Nations Inuit, and non-Indigenous women by northern versus southern residence, Quebec. J Epidemiol Community Health 2012; 66(4): 328-333.

Periodontal disease is not associated with preeclampsia in Canadian pregnant women - Taghzouti N, Xiong X, Gornitsky M, Chandad F, Voyer R, Gagnon G, Leduc L, Xu H, Tulandi T, Wei B, Senécal J, Velly AM, Salah MH, Fraser W. Periodontal disease is not associated with preeclampsia in Canadian pregnant women. J Periodont 2012; 83(7): 871-877.

Association of uric acid with progression to preeclampsia and development of adverse conditions in gestational hypertensive pregnancies - Wu Y, Xiong X, Fraser W, Luo ZC. Association of uric acid with progression to preeclampsia and development of adverse conditions in gestational hypertensive pregnancies. J Hypertension 2012; 25(6): 711-717.

Early versus late amniotomy for labour induction: a randomized controlled trial - Gagnon-Gervais K, Bujold E, Iglesias MH, Duperron L, Masse A, Mayrand MH, Sansregret A, Fraser W, Audibert F. Early versus late amniotomy for labour induction: a randomized controlled trial. J Matern Fetal Neonatal Med 2012; 25(11): 2326-2329.

Obstetric intervention - Zhang J, Joseph KS, Fraser W. Obstetric intervention. Dans: Buck Louis G, Platt RW (eds). Reproductive and Perinatal Epidemiology. New York (NY). Oxford University Press, 2011; 129-151.

The facilitating factors and barriers encountered in the adoption of a humanized birth care approach in a highly specialized university affiliated hospital - Behruzi R, Hatem M, Goulet L, Fraser W. The facilitating factors and barriers encountered in the adoption of a humanized birth care approach in a highly specialized university affiliated hospital. BMC Womens Health 2011; 11: 53 (on line).

Reporting results of human biomonitoring of environmental chemicals to study participants: a comparison of approaches followed in two Canadian studies - Haines DA, Arbuckle TE, Lye E, Legrand M, Fisher M, Langlois R, Fraser W. Reporting results of human biomonitoring of environmental chemicals to study participants: a comparison of approaches followed in two Canadian studies. J Epidemiol Community Health 2011; 65(3): 191-198.

Birth technology and maternal roles in birth: knowledge and attitudes of canadian women approaching childbirth for the first time - Klein MC, Kaczorowski J, Hearps SJ, Tomkinson J, Baradaran N, Hall WA, McNiven PC, Brant R, Grant J, Doré S, Brasset-Latulippe A, Fraser W. Birth technology and maternal roles in birth: knowledge and attitudes of canadian women approaching childbirth for the first time. J Obstet Gynaecol Can 2011; 33(6): 598-608.

Duration of passive and active phases of the second stage of labour and risk of severe postpartum haemorrhage in low-risk nulliparous women - Le Ray C, Fraser W, Rozenberg P, Langer B, Subtil D, Goffinet F, PREMODA Study Group. Duration of passive and active phases of the second stage of labour and risk of severe postpartum haemorrhage in low-risk nulliparous women. Eur J Obstet Gynecol Reprod Biol 2011; 158(2): 167-172.

The trial to reduce IDDM in the genetically at risk (TRIGR) study: recruitment, intervention and follow-up - TRIGR Study Group, Fraser W. The trial to reduce IDDM in the genetically at risk (TRIGR) study: recruitment, intervention and follow-up. Diabetologia 2011; 54(3): 627-633.

Relative validity of a food frequency questionnaire for Canadian pregnant women - Shatenstein B, Xu H, Luo ZC, Fraser W. Relative validity of a food frequency questionnaire for Canadian pregnant women. Can J Diet Pract Res 2011; 72(2): 60-69.

Diabetes in pregnancy may differentially affect neonatal outcomes for twins and singletons - Luo ZC, Simonet F, Wei S, Xu H, Rey E, Fraser W. Diabetes in pregnancy may differentially affect neonatal outcomes for twins and singletons. Diabet Med 2011; 28(9): 1068-1073.

Risk factors for severe neonatal acidosis - Maisonneuve E, Audibert F, Guilbaud L, Lathelize J, Jousse M, Pierre F, Fraser W, Carbonne B. Risk factors for severe neonatal acidosis. Obstet Gynecol 2011; 118(4): 818-823.

Prevention of adverse pregnancy outcomes with low-dose ASA in early pregnancy: new perspectives for future randomized trials - Bujold E, Tapp S, Audibert F, Ferreira E, Forest JC, Rey E, Fraser W, Chaillet N, Giguere Y. Prevention of adverse pregnancy outcomes with low-dose ASA in early pregnancy: new perspectives for future randomized trials. J Obstet Gynaecol Can 2011; 33(5): 480-483.

Incidence, risk factors, and associated complications of eclampsia - Liu S, Joseph KS, Liston RM, Bartholomew S, Walker M, León JA, Kirby RS, Sauvé R, Kramer MS, Fraser W, Maternal Health Study Group of Canadian Perinatal Surveillance System (Public Health Agency of Canada). Incidence, risk factors, and associated complications of eclampsia. Obstet Gynecol 2011; 118(5): 987-994.

Attitudes of the new generation of Canadian obstetricians: how do they differ from their predecessors? - Klein MC, Liston R, Fraser W, Baradaran N, Hearps SJ, Tomkinson J, Kaczorowski J, Brant R, Maternity Care Research Group. Attitudes of the new generation of Canadian obstetricians: how do they differ from their predecessors?. Birth 2011; 38(2): 129-139.

High-dose vs low-dose oxytocin for labor augmentation: a systematic review - Wei SQ, Luo ZC, Qi HP, Xu H, Fraser W. High-dose vs low-dose oxytocin for labor augmentation: a systematic review. Am J Obstet Gynecol 2010; 203(4): 296-304.

Meta-analyses - Xu H, Fraser W. Meta-analyses. Dans: Sheiner E (ed). Perinatal Epidemiology. Philadelphia (PA). Nova Science Publishers, 2010; ISBN: 978-1-60741-648-7.

Inflammatory cytokines and spontaneous preterm birth in asymptomatic women: a systematic review - Wei S, Fraser W, Luo ZC. Inflammatory cytokines and spontaneous preterm birth in asymptomatic women: a systematic review. Obstet Gynecol 2010; 116(2 Pt 1): 393-401.

The natural history of the normal first stage of labor - Zhang J, Troendle J, Mikolajczyk R, Sundaram R, Beaver J, Fraser W. The natural history of the normal first stage of labor. Obstet Gynecol 2010; 115(4): 705-710.

Contingent use of fetal Fibronectin testing and cervical length measurement inwomen with preterm labor - Audibert F, Fortin S, Delvin EE, Djemli A, Brunet S, Dubé J, Fraser W. Contingent use of fetal Fibronectin testing and cervical length measurement inwomen with preterm labor. J Obstet Gynaecol Can 2010; 32(4): 307-312.

Twin-twin transfusion syndrome: an ethics-based and evidence-based argument for clinical research - Stamilio DM, Fraser W, Moore TR. Twin-twin transfusion syndrome: an ethics-based and evidence-based argument for clinical research. Am J Obstet Gynecol 2010; 203(1): 3-16.

Middle cerebral artery Doppler in fetomaternal hemorrhage - Huissoud C, Fraser W, Rudigoz RC, Audibert F. Middle cerebral artery Doppler in fetomaternal hemorrhage. J Matern Fetal Neonatal Med 2010; 23(6): 573-575.

Risk ractors for early and late onset of respiratory symptoms in babies born through meconium - Xu H, Calvet M, Wei S, Luo ZC, Fraser W. Risk ractors for early and late onset of respiratory symptoms in babies born through meconium. Am J Perinatol 2010; 27(4): 271-278.

Humanized birth in high risk pregnancy: barriers and facilitating factors - Behruzi R, Hatem M, Goulet C, Fraser W, Leduc N, Misago C. Humanized birth in high risk pregnancy: barriers and facilitating factors. Med Health Care Philos. 2010; 13(1): 49-58.

Large prospective birth cohort studies on environmental contaminants and child health - Goals, challenges, limitations and needs - Luo ZC, Liu JM, Fraser W. Large prospective birth cohort studies on environmental contaminants and child health - Goals, challenges, limitations and needs. Med Hypotheses 2010; 74(2): 318-324.

Birth outcomes and infant mortability by the degree of rural isolation among First Nations and non-First Nations in Manitoba, Canada - Luo ZC, Wilkins R, Heaman M, Martens P, Smylie J, Hart L, Simonet F, Wassimi S, Wu Y, Fraser W. Birth outcomes and infant mortability by the degree of rural isolation among First Nations and non-First Nations in Manitoba, Canada. J Rural Health 2010; 26(2): 175-181.

Maternal glucose tolerance in pregnancy affects fetal insulin sensitivity - Luo ZC, Delvin EE, Fraser W, Audibert F, Deal C, Julien P, Girard I, Shear R, Levy E, Nuyt A-M. Maternal glucose tolerance in pregnancy affects fetal insulin sensitivity. Diabetes Care 2010; 33(9): 2055-2061.

Existence of compensatory defense mechanisms against oxidative stress and hypertension in preeclampsia - Roland L, Gagné A, Bélanger M-C, Boutet M, Berthiaume L, Fraser W, Julien P, Bilodeau JF. Existence of compensatory defense mechanisms against oxidative stress and hypertension in preeclampsia. Hypertension in Pregnancy 2010; 29(1): 21-37.

Individual- and community-level disparities in birth outcomes and infant mortality among First Nations, Inuit and other populations in Quebec - Simonet F, Wassimi S, Heaman M, Smylie J, Martens P, Nancy GLM, Labranche E, Wilkins R, Fraser W, Luo ZC. Individual- and community-level disparities in birth outcomes and infant mortality among First Nations, Inuit and other populations in Quebec. Open Women's Health J 2010; 4: 18-24.

Urban living is not associated with better birth and infant outcomes among Inuit and First Nations in Quebec - Simonet F, Wilkins R, Heaman M, Smylie J, Martens P, Nancy GLM, Labranche E, Wassimi S, Fraser W, Luo ZC. Urban living is not associated with better birth and infant outcomes among Inuit and First Nations in Quebec. Open Women's Health J 2010; 4: 25-31.

Community remoteness, perinatal outcomes and infant mortality among First Nations in Quebec - Wassimi S, Nancy GLM, Wilkins R, Heaman M, Martens P, Smylie J, Simonet F, Fraser W, Luo ZC. Community remoteness, perinatal outcomes and infant mortality among First Nations in Quebec. Open Women's Health J 2010; 4: 32-38.

Does living on-reserve versus off-reserve make a difference in First Nations birth outcomes in Manitoba, Canada? - Heaman M, Martens P, Hart L, Smylie J, Agnew E, Simonet F, Wassimi S, Fraser W, Luo ZC. Does living on-reserve versus off-reserve make a difference in First Nations birth outcomes in Manitoba, Canada? . Open Women's Health J 2010; 4: 39-45.

North-south gradients in adverse birth outcomes for First Nations and others in Manitoba, Canada - Martens P, Heaman M, Hart L, Wilkins R, Smylie J, Wassimi S, Simonet F, Wu F, Fraser W, Luo ZC. North-south gradients in adverse birth outcomes for First Nations and others in Manitoba, Canada. Open Women's Health J 2010; 4: 46-54.

Neighborhood socioeconomic characteristics, birth outcomes and infant mortality among First Nations and non-First Nations in Manitoba, Canada - Luo ZC, Wilkins R, Heaman M, Martens P, Smylie J, Hart L, Wassimi S, Simonet F, Wu Y, Fraser W. Neighborhood socioeconomic characteristics, birth outcomes and infant mortality among First Nations and non-First Nations in Manitoba, Canada. Open Women's Health J 2010; 4: 55-64.

High-dose vs low-dose oxytocin for labor augmentation: a systematic review - Wei S, Luo ZC, Qi HP, Xu H, Fraser W. High-dose vs low-dose oxytocin for labor augmentation: a systematic review. Am J Obstet Gynecol 2010; 203(4): 296-304.

Facilitators and barriers in the humanization of childbirth practice in Japan - Behruzi R, Hatem M, Fraser W, Goulet L, Ii M, Misago C. Facilitators and barriers in the humanization of childbirth practice in Japan. BMC Pregnancy and Childbirth 2010; 10: 25 (on line).

An international trial of antioxidants in the prevention of preeclampsia (INTAPP) - Xu H, Perez-Cuevas R, Xiong X, Reyes H, Roy C, Julien P, Smith G, von Dadelszen P, Leduc L, Audibert F, Moutquin JM, Piedboeuf B, Shatenstein B, Parra-Cabrera S, Choquette P, Winsor S, Wood S, Benjamin A, Walker M, Helewa ME, Dubé J, Tawagi G, Seaward G, Ohlsson A, Magee LA, Olatunbosun O, Gratton R, Shear R, Demianczuk N, Collet JP, Wei S, Fraser W, INTAPP study group. An international trial of antioxidants in the prevention of preeclampsia (INTAPP). Am J Obstet Gynecol 2010; 202(3): 239.e1-239.e10.

Caffeine for apnea of prematurity trial: benefits may vary in subgroups - Davis P, Schmidt B, Roberts RS, Doyle LW, Asztalos E, Haslam R, Sinha S, Tin W, Barrington K, Fraser W, Caffeine for Apnea of Prematurity Trial Group. Caffeine for apnea of prematurity trial: benefits may vary in subgroups. J Pediatr 2010; 156(3): 382-387.

Severe maternal morbidity in Canada, 2003 to 2007: surveillance using routine hospitalization data and ICD-10CA codes - Joseph KS, Liu S, Rouleau J, Kirby RS, Kramer MS, Sauvé R, Fraser W, Young DC, Lister P, Maternal Health Study Group of Canadian Perinatal Surveillance System (Public Health Agency of Canada). Severe maternal morbidity in Canada, 2003 to 2007: surveillance using routine hospitalization data and ICD-10CA codes. J Obstet Gynaecol Can 2010; 32(4): 307-312.

Maternal mortality and severe maternal morbidity surveillance in Canada - Allen V, Campbell M, Carson G, Fraser W, Liston RM, Walker M, Barrett J, Canadian Maternal Morbidity Working Group. Maternal mortality and severe maternal morbidity surveillance in Canada. J Obstet Gynaecol Can 2010; 32(12): 1140-1146.

Fetal abdominal scarring caused by the umbilical cord of a cotwin following selective cord coagulation - Taillefer C, Fraser W, Audibert F. Fetal abdominal scarring caused by the umbilical cord of a cotwin following selective cord coagulation. Ultrasound Med Biol 2009; 34(4): 482-483.

Diagnosis, management, and evaluation of hypertensive disorders of pregnancy - Aleksandrov N, Fraser W, Audibert F. Diagnosis, management, and evaluation of hypertensive disorders of pregnancy. J Obstet Gynaecol Can 2009; 30(11): 1000; author reply 1000-1.

The effect of early oxytocin augmentation in labor: a meta-analysis - Wei S, Luo ZC, Xu H, Fraser W. The effect of early oxytocin augmentation in labor: a meta-analysis. Obstet Gynecol 2009; 111(3): 641-649. Erratum in: 2010; 116(1): 196.

Tea consumption during pregnancy and the risk of pre-eclampsia - Wei S, Xu H, Xiong X, Luo ZC, Audibert F, Fraser W. Tea consumption during pregnancy and the risk of pre-eclampsia. Int J Gynecol Obstet 2009; 105(2): 123-126.

Abnormal fetal heart rate tracing patterns in patients with thick meconium staining of the amniotic fluid: association with perinatal outcomes - Xu H, Mas-Calvet M, Wei S, Luo ZC, Fraser W. Abnormal fetal heart rate tracing patterns in patients with thick meconium staining of the amniotic fluid: association with perinatal outcomes. Am J Obstet Gynecol 2009; 200(3): 283.e1-7.

When to stop pushing: effects of duration of second-stage expulsion efforts on maternal and neonatal outcomes in nulliparous women with epidural analgesia - Le Ray C, Audibert F, Goffinet F, Fraser W. When to stop pushing: effects of duration of second-stage expulsion efforts on maternal and neonatal outcomes in nulliparous women with epidural analgesia. Am J Obstet Gynecol 2009; 201(4): 361.e1-7.

QUARITE (quality of care, risk management and technology in obstetrics): a cluster-randomized trial of a multifaceted intervention to improve emergency obstetric care in Senegal and Mali - Dumont A, Fournier P, Fraser W, Haddad S, Traore M, Diop I, Gueye M, Gaye A, Couturier F, Pasquier JC, Beaudoin F, Lalonde A, Hatem M, Abrahamowicz M. QUARITE (quality of care, risk management and technology in obstetrics): a cluster-randomized trial of a multifaceted intervention to improve emergency obstetric care in Senegal and Mali. Trials 2009; 10: 85 (on line).

Early amniotomy and early oxytocin for prevention of, or therapy for, delay in first stage spontaneous labour compared with routine care - Wei S, Wo BL, Xu H, Luo ZC, Roy C, Fraser W. Early amniotomy and early oxytocin for prevention of, or therapy for, delay in first stage spontaneous labour compared with routine care. Cochrane DB Syst Rev 2009; 2: CD006794.

Primary birthing attendants and birth outcomes in remote Inuit communities - a natural "experiment" in Nunavik, Canada - Simonet F, Wilkins R, Labranche E, Smylie J, Heaman M, Martens P, Fraser W, Minich K, Wu Y, Carry C, Luo ZC. Primary birthing attendants and birth outcomes in remote Inuit communities - a natural "experiment" in Nunavik, Canada. J Epidemiol Community Health 2009; 63(7): 546-551.

Absorption, transport, and bioavailability of vitamin e and its role in pregnant women - Gagné A, Wei S, Fraser W, Julien P. Absorption, transport, and bioavailability of vitamin e and its role in pregnant women. J Obstet Gynaecol Can 2009; 31(3): 210-217.

Role of nutrition in the risk of preeclampsia - Xu H, Shatenstein B, Luo ZC, Wei S, Fraser W. Role of nutrition in the risk of preeclampsia. Nutr Rev 2009; 67(11): 639-657.

The attitudes of Canadian maternity care practitioners towards labour and birth: many differences but important similarities - Klein MC, Kaczorowski J, Hall WA, Fraser W, Liston RM, Eftekhary S, Brant R, Mâsse LC, Rosinski J, Mehrabadi A, Baradaran N, Tomkinson J, Doré S, McNiven PC, Saxell L, Lindstrom K, Grant J, Chamberlaine A. The attitudes of Canadian maternity care practitioners towards labour and birth: many differences but important similarities. J Obstet Gynaecol Can 2009; 31(9): 827-840.

Quitting smoking during early versus late pregnancy: the risk of preeclampsia and adverse birth outcomes. - Xiong X, Zhang J, Fraser W. Quitting smoking during early versus late pregnancy: the risk of preeclampsia and adverse birth outcomes.. J Obstet Gynaecol Can 2009; 31(8): 702-707.

Accuracy of recall in quality-of-life assessment among women operated on for stress urinary incontinence - Larochelle A, Podoba J, Ouellet S, Fraser W. Accuracy of recall in quality-of-life assessment among women operated on for stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct 2009; 20(10): 1233-1441.

Impact of pain level on second-stage delivery outcomes among women with epidural analgesia: Results from the PEOPLE study - Abenhaim HA, Fraser W. Impact of pain level on second-stage delivery outcomes among women with epidural analgesia: Results from the PEOPLE study. Am J Obstet Gynecol 2008; 199(5): 500.e1-6.

Review: misoprostol and intramuscular prostaglandins do not prevent postpartum haemorrhage more than injectable uterotonics - Wei S, Fraser W. Review: misoprostol and intramuscular prostaglandins do not prevent postpartum haemorrhage more than injectable uterotonics. Evid Based Med 2008; 13(3): 82.

Patterns of pregnancy exposure to prescription FDA C, D and X drugs in a Canadian population - Wen SW, Yang T, Krewski D, Yang Q, Nimrod C, Garner PR, Fraser W, Olatunbosun O, Walker M. Patterns of pregnancy exposure to prescription FDA C, D and X drugs in a Canadian population. J Perinatol 2008; 28(5): 324-329.

Exploring heterogeneity in meta-analyses: needs, resources and challenges - Xu H, Platt RW, Luo ZC, Wei S, Fraser W. Exploring heterogeneity in meta-analyses: needs, resources and challenges. Pediatr Perinat Epidemiol 2008; 22 (suppl. 1): 18-28.

Maternal characteristics associated with pregnancy exposure to FDA category C, D, and X drugs in a Canadian population - Yang T, Walker M, Krewski D, Yang Q, Nimrod C, Garner PR, Fraser W, Olatunbosun O, Wen SW. Maternal characteristics associated with pregnancy exposure to FDA category C, D, and X drugs in a Canadian population. Pharmacoepidemiol Drug Safety 2008; 17(3): 270-277.

Effect on birth outcomes of a formalised approach to care in hospital labour assessment units: international, randomised controlled trial - Hodnett E, Stremler R, Willan AR, Weston JA, Lowe NK, Simpson KR, Fraser W, Gafni A, SELAN (Structured Early Labour Assessment and Care by Nurses) Trial Group. Effect on birth outcomes of a formalised approach to care in hospital labour assessment units: international, randomised controlled trial. BMJ 2008; 337: a1021.

Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes - Wen SW, Zhou J, Yang Q, Fraser W, Olatunbosun O, Walker M. Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes. CMAJ 2008; 179(12): 1263-1268.

Obstetric approaches to the prevention of meconium aspiration syndrome - Xu H, Wei S, Fraser W. Obstetric approaches to the prevention of meconium aspiration syndrome. J Perinatol 2008; 28 (suppl 3): S14-18.

Induction of labour post-term or expectant management with serial fetal monitoring had similar neonatal outcomes - Wei S, Fraser W. Induction of labour post-term or expectant management with serial fetal monitoring had similar neonatal outcomes. Evid Based Med 2007; 12(1): 174.

Review: planned early birth after prelabour rupture of membranes at term has benefits for mother and infant - Abenhaim HA, Fraser W. Review: planned early birth after prelabour rupture of membranes at term has benefits for mother and infant. Evid Based Med 2007; 12(1): 16.

Review: planned early birth after prelabour rupture of membranes at term has benefits for mother and infant - Abenhaim L, Fraser W. Review: planned early birth after prelabour rupture of membranes at term has benefits for mother and infant. Arch Dis Child Educ Pract Ed 2007; 92(4): ep125.

Pregnancy-induced hypertension and perinatal mortality - Xiong X, Buekens P, Pridjian G, Fraser W. Pregnancy-induced hypertension and perinatal mortality. J Reprod Med 2007; 52(5): 402-406.

Intrapartum amnioinfusion for meconium-stained amniotic fluid: a systematic review of randomised controlled trials - Xu H, Hofmeyer J, Roy C, Fraser W. Intrapartum amnioinfusion for meconium-stained amniotic fluid: a systematic review of randomised controlled trials. BJOG 2007; 114(4): 383-390.

Factors associated with postpartum urinary/anal incontinence in primiparous women in Quebec - Hatem M, Pasquier JC, Fraser W, Lepire E. Factors associated with postpartum urinary/anal incontinence in primiparous women in Quebec. J Obstet Gynaecol Can 2007; 29(3): 232-239.

Occurrence and determinants of trimethoprim/sulfamethoxazole use in pregnancy - Yang T, Walker M, Krewski D, Yang Q, Garner PR, Fraser W, Olatunbosun O, Nimrod C, Wen SW. Occurrence and determinants of trimethoprim/sulfamethoxazole use in pregnancy. Acta Obstet Gynecol Scand 2007; 86(11): 1310-1316.

The effects and mechanisms of primiparity on the risk of preeclampsia: A systematic review - Luo ZC, An N, Xu H-R, Larante A, Audibert F, Fraser W. The effects and mechanisms of primiparity on the risk of preeclampsia: A systematic review. Paediatr Perinat Epidemiol 2007; 21 (suppl. 1): 36-45.

Tracing the origins of " fetal origins " of adult diseases: programming by oxidative stress? - Luo ZC, Fraser W, Julien P, Deal C, Audibert F, Smith GN, Xiong X, Walker M. Tracing the origins of " fetal origins " of adult diseases: programming by oxidative stress? . Med Hypotheses 2006; 66(1): 38-44.

Evidence-based strategies for implementing Guidelines in Obstetrics: a systematic review - Chaillet N, Dubé E, Dugas M, Audibert F, Tourigny C, Fraser W, Dumont A. Evidence-based strategies for implementing Guidelines in Obstetrics: a systematic review. Obstet Gynecol 2006; 108(5): 1234-1245.

Effect on neonatal outcomes in gestational hypertension in twin compared with singleton pregnancies - Luo ZC, Simonet F, An N, Bao FY, Audibert F, Fraser W. Effect on neonatal outcomes in gestational hypertension in twin compared with singleton pregnancies. Obstet Gynecol 2006; 108(5): 1138-1144.

Periodontal disease and adverse pregnancy outcomes: a systematic review - Xiong X, Buekens P, Fraser W, Beck J, Offenbacher S. Periodontal disease and adverse pregnancy outcomes: a systematic review. BJOG 2006; 113(2): 135-143.

Selective serotonin reuptake inhibitors and adverse pregnancy outcomes - Wen SW, Yang Q, Fraser W, Olatunsobun O, Nimrod C, Walker M. Selective serotonin reuptake inhibitors and adverse pregnancy outcomes. Am J Obstet Gynecol 2006; 194(4): 961-966.

The vitamin E debate: implications for ongoing trials of pre-eclampsia prevention - Fraser W, Audibert F, Bujold E, Leduc L, Xu H, Boulvain M, Julien P. The vitamin E debate: implications for ongoing trials of pre-eclampsia prevention. Brit J Obstet Gynaec 2005; 112(6): 684-688.

Amnioinfusion for the prevention of the meconium aspiration syndrome - Fraser W, Hofmeyer J, Lede R, Faron G, Alexander S, Goffinet F, Ohlsson A, Goulet C, Turcot-Lemay L, Prendiville W, Marcoux S, Laperrière L, Roy C, Petrou S, Xu H, Wei B, for the Amnioinfusion Trial Group, Audibert F. Amnioinfusion for the prevention of the meconium aspiration syndrome. N Engl J Med 2005; 353(9): 909-917.

Pregnancy-induced hypertension and infant growth at 28 and 42 days postpartum - Baulon E, Fraser W, Piedboeuf B, Buekens P, Xiong X. Pregnancy-induced hypertension and infant growth at 28 and 42 days postpartum. BMC Pregnancy and Childbirth 2005; 5(1): 10.

Postpartum urinary and anal incontinence: a population-based study of quality of life of primiparous women in Quebec - Hatem M, Fraser W, Lepire E. Postpartum urinary and anal incontinence: a population-based study of quality of life of primiparous women in Quebec. J Obstet Gynaecol Can 2005; 27(7): 682-688.

Prevalence, management, and outcome sof preterm prelabour rupture of the membrane of women in Canada - Smith G, Rafuse C, Anand N, Brennan B, Connors G, Cane J, Fraser W, Gratton R, Moutquin JM, Scott H, Schneider C, Walker M. Prevalence, management, and outcome sof preterm prelabour rupture of the membrane of women in Canada. J Obstet Gynaecol Can 2005; 66(1): 38-44.

Effect of fetal position on second-stage duration and labor outcome - Senécal J, Xiong X, Fraser W, and the PEOPLE (Pushing Early of Pushing Late with Epidural) Study Group. Effect of fetal position on second-stage duration and labor outcome. Obstet Gynecol 2005; 105(4): 763-772.

Prostaglandin E2 vaginal gel to treat dystocia in spontaneous labour: a multicentre randomised placebo-controlled trial - Oppenheimer LW, Labrecque M, Wells G, Bland ES, Fraser W, Eason E, Brisson-Carroll G, Yetisir E. Prostaglandin E2 vaginal gel to treat dystocia in spontaneous labour: a multicentre randomised placebo-controlled trial. BJOG 2005; 112(5): 612-618.

Impact of pregnancy-induced hypertension on birthweight by gestational age - Xiong X, Fraser W. Impact of pregnancy-induced hypertension on birthweight by gestational age. Paediatr Perinat Epidemiol 2004; 18(3): 186-191.

The Prevention of Pre-eclampsia - Takser L, Fraser W. The Prevention of Pre-eclampsia. Dans: Pre-eclampsia: Current Perspectives on Management. Boca Raton, London, New York, Washington, DC. The Parthenon Publishing Group, 2004; 243-257.

History of abortion, preterm and term birth, and risk of gestational hypertension: a population-based study - Xiong X, Fraser W, Demianczuk N. History of abortion, preterm and term birth, and risk of gestational hypertension: a population-based study. J Reprod Med 2004; 49(11): 899-907.

Choix du paradigme éducationel pour la formation de sages-femmes au Québec - Hatem M, Fraser W, Blais R, Levy R. Choix du paradigme éducationel pour la formation de sages-femmes au Québec. Rupture 2003; 9(1): 86-102.

Anemia during pregnancy in a Chinese population - Xiong X, Buekens P, Fraser W, Guo Z. Anemia during pregnancy in a Chinese population. Int J Gynecol Obstet 2003; 83(2): 159-164.

The management of VBAC at term: a survey of Canadian obstetricians - Brill Y, Kingdom J, Thomas J, Fraser W, Milne JK, Thomas M, Windrim R. The management of VBAC at term: a survey of Canadian obstetricians. J Obstet Gynaecol Can 2003; 25(4): 300-310.

Risk factors for difficult delivery in nulliparas with epidural analgesia in second stage of labor - Fraser W, Cayer M, Soeder BM, Turcot L, Marcoux S, for the PEOPLE study group. Risk factors for difficult delivery in nulliparas with epidural analgesia in second stage of labor. Obstet Gynecol 2002; 99(3): 409-418.

History of abortion, preterm, term birth, and risk of preeclampsia: a population-based study - Xiong X, Fraser W, Demianczuk N. History of abortion, preterm, term birth, and risk of preeclampsia: a population-based study. Am J Obstet Gynecol 2002; 187(4): 1013-1018.

Reply: Association of preeclampsia with high birth weight for gestational age (lettre è l'éditeur) - Xiong X, Fraser W. Reply: Association of preeclampsia with high birth weight for gestational age (lettre è l'éditeur). Am J Obstet Gynecol 2002; 186: 1105-1106.

The impact of preeclampsia and gestational hypertension on birth weight by gestational age - Xiong X, Demianczuk N, Duncan Saunders L, Wang F, Fraser W. The impact of preeclampsia and gestational hypertension on birth weight by gestational age. Am J Epidemiol 2002; 155(3): 203-209.

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