Chercheur

    Guy Grimard , M.D.

    guy_grimard@ssss.gouv.qc.ca
    Guy Grimard
    Axe de recherche
    Maladies musculosquelettiques et réadaptation
    Thème de recherche
    Étude des déformations du rachis et des pathologies musculosquelettiques
    Adresse
    CHUSJ - Centre de Recherche

    Téléphone
    514 345-4931 #4876

    Fax
    514 345-4755

    Sommaire de carrière

    Guy Grimard est un chirurgien orthopédiste gradué de l'Université de Montréal qui a complété une spécialité en orthopédie pédiatrique au CHU Sainte-Justine, au Royal Children's Hospital de Melbourne et à l'Hôpital Debrousse de Lyon en 1993 et 1994. Il a également complété une maîtrise en épidémiologie clinique en 1992. Il est professeur adjoint de clinique au département de chirurgie et chirurgien orthopédique au CHU Sainte-Justine depuis 1994.

    Ses intérêts de recherche sont orientés vers les facteurs pronostiques de la progression de la scoliose idiopathique de l'adolescent, l'analyse biomécanique et clinique des fractures du coude chez l'enfant, ainsi que l'épidémiologie clinique des blessures de l'enfant.

Publications

Spondylolisthesis, sacro-pelvic morphology and orientation in young gymnasts - Toueg CW, Mac-Thiong J-M, Grimard G, Poitras B, Parent S, Labelle H. Spondylolisthesis, sacro-pelvic morphology and orientation in young gymnasts. J Spinal Disord Tech 2014; (sous presse).

Knowledge and management of Adolescent Idiopathic Scoliosis among family physicians, pediatricians, chiropractors and physiotherapists in Québec, Canada: An exploratory study - Théroux J, Grimard G, Beauséjour M, Labelle H, Feldman D. Knowledge and management of Adolescent Idiopathic Scoliosis among family physicians, pediatricians, chiropractors and physiotherapists in Québec, Canada: An exploratory study. J Can Chiropr Assoc 2013; 57(3): 251-259.

A non-synonymous coding variant (L616F) in the TLR5 gene is potentially associated with Crohn's disease and influences responses to bacterial flagellin - Sheridan J, Mack DR, Amre D, Israel D, Cherkasov A, Li H, Grimard G, Steiner TS. A non-synonymous coding variant (L616F) in the TLR5 gene is potentially associated with Crohn's disease and influences responses to bacterial flagellin. PLoS ONE 2013; 8(4): e61326.

Association between the PTPN2 gene and Crohn's disease: dissection of potential causal variants - Marcil V, Mack D, Kumar V, Faure C, Carlson CS, Beaulieu P, Israel D, Krupoves A, Costea I, Lambrette P, Grimard G, Dong J, Seidman E, Amre D, Levy E. Association between the PTPN2 gene and Crohn's disease: dissection of potential causal variants. Inflamm Bowel Dis 2013; 19(6): 1149-1155.

Microarray expression profiling identifies genes with altered expression in Adolescent Idiopathic Scoliosis - Fendri K, Patten S, Kaufman G, Zaouter C, Parent S, Grimard G, Edery P, Moldovan F. Microarray expression profiling identifies genes with altered expression in Adolescent Idiopathic Scoliosis. Eur Spine J 2013; 22(6): 1300-1311.

Genome-wide association study signal at the 12q12 locus for Crohn's disease may represent associations with the MUC19 gene - Kumar V, Mack DR, Marcil V, Israel D, Krupoves A, Costea I, Lambrette P, Grimard G, Dong J, Seidman EG, Amre D, Levy E. Genome-wide association study signal at the 12q12 locus for Crohn's disease may represent associations with the MUC19 gene. Inflamm Bowel Dis 2013; 19(6): 1254-1259.

Quantitative evaluation of an automatic segmentation method for 3D reconstruction of intervertebral scoliotic disks from MR images - Chevrefils C, Cheriet F, Grimard G, Miron MC, Aubin C-É. Quantitative evaluation of an automatic segmentation method for 3D reconstruction of intervertebral scoliotic disks from MR images. BMC Med Imag 2012; 12(1): 26 (1-14).

NELL1, NCF4, and FAM92B genes are not major susceptibility genes for Crohn's disease in canadian children and young adults - Amre D, Mack D, Israel D, Krupoves A, Costea I, Lambrette P, Grimard G, Dong J, Levy E. NELL1, NCF4, and FAM92B genes are not major susceptibility genes for Crohn's disease in canadian children and young adults. Inflamm Bowel Dis 2012; 18(3): 529-535.

In vivo dynamic bone growth modulation is less detrimental but as effective as static growth modulation - Valteau B, Grimard G, Londono I, Moldovan F, Villemure I. In vivo dynamic bone growth modulation is less detrimental but as effective as static growth modulation. Bone 2011; 49(5): 996-1004.

Objective grading of the pivot shift phenomenon using a support vector machine approach - Labbe D, de Guise JA, Mezghani N, Godbout V, Grimard G, Baillargeon D, Lavigne P, Fernandes J, Ranger P, Hagemeister N. Objective grading of the pivot shift phenomenon using a support vector machine approach. J Biomech 2011; 44(1): 1-5.

Accounting for velocity of the pivot shift test manoeuvre decreases kinematic variability - Labbe D, de Guise JA, Godbout V, Grimard G, Baillargeon D, Lavigne P, Fernandes J, Massé V, Ranger P, Hagemeister N. Accounting for velocity of the pivot shift test manoeuvre decreases kinematic variability. Knee 2011; 18(2): 88-93.

Validation and clinical relevance of a French-Canadian version of the spinal appearance questionnaire in adolescent patients - Roy-Beaudry M, Beauséjour M, Joncas J, Forcier M, Bekhiche S, Labelle H, Grimard G, Parent S. Validation and clinical relevance of a French-Canadian version of the spinal appearance questionnaire in adolescent patients. Spine 2011; 36(9): 746-751.

Prevalence of spondylolisthesis in a population of gymnasts - Toueg CW, Mac-Thiong J-M, Grimard G, Parent S, Poitras B, Labelle H. Prevalence of spondylolisthesis in a population of gymnasts. Dans: Aubin C-E, Stokes AIF, Labelle H, Moreau A (eds). Research into Spinal Deformities VII (Studies in Health Technology and Informatics). Netherlands. IOS Press, 2010; 132-137.

Association between genome-wide association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children - Amre D, Mack D, Morgan K, Israel D, Deslandres C, Seidman E, Lambrette P, Costea I, Krupoves A, Feguery H, Dong J, Zhu Z, Grimard G, Levy E. Association between genome-wide association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children. Hum Genet 2010; 128(2): 131-135.

Feature selection using a principal component analysis of the kinematics of the pivot shift phenomenon - Labbe D, de Guise JA, Mezghani N, Godbout V, Grimard G, Baillargeon D, Lavigne P, Fernandes J, Ranger P, Hagemeister N. Feature selection using a principal component analysis of the kinematics of the pivot shift phenomenon. J Biomech 2010; 43(16): 3080-3084.

Genes involved in the metabolism of poly-unsaturated fatty-acids (PUFA) and risk for Crohn's disease in children & young adults - Costea I, Mack D, Israel D, Morgan K, Krupoves A, Seidman E, Deslandres C, Lambrette P, Grimard G, Levy E, Amre D. Genes involved in the metabolism of poly-unsaturated fatty-acids (PUFA) and risk for Crohn's disease in children & young adults. PLoS ONE 2010; 5(12): e15672.

Susceptibility loci reported in genome-wide association studies are associated with Crohn's disease in Canadian children - Amre D, Mack D, Morgan K, Israel D, Deslandres C, Seidman E, Lambrette P, Costea I, Krupoves A, Feguery H, Dong H, Grimard G, Levy E. Susceptibility loci reported in genome-wide association studies are associated with Crohn's disease in Canadian children. Aliment Pharmacol Therap 2010; 31(11): 1186-1191.

Cell-based screening test for idiopathic scoliosis using cellular dielectric spectroscopy - Akoume MY, Azeddine B, Turgeon I, Franco A, Labelle H, Poitras B, Rivard C-H, Grimard G, Ouellet J, Parent S, Moreau A. Cell-based screening test for idiopathic scoliosis using cellular dielectric spectroscopy. Spine 2010; 35(13): E601-608.

Effects of in vivo static compressive loading on aggrecan and type II and X collagens in the rat growth plate extracellular matrix - Cancel M, Grimard G, Crisinel DT, Moldovan F, Villemure I. Effects of in vivo static compressive loading on aggrecan and type II and X collagens in the rat growth plate extracellular matrix. Bone 2009; 44(2): 306-315.

Autophagy gene ATG16L1 but not IRGM is associated with Crohn's disease in Canadian children - Amre D, Mack D, Morgan K, Krupoves A, Costea I, Lambrette P, Grimard G, Dong J, Feguery H, Bucionis V, Deslandres C, Levy E, Seidman EG. Autophagy gene ATG16L1 but not IRGM is associated with Crohn's disease in Canadian children. Inflamm Bowel Dis 2009; 15(4): 501-507.

Interleukin 10 (IL-10) gene variants and susceptibility for pediatric onset Crohn's disease - Amre D, Mack D, Morgan K, Israel D, Lambrette P, Costea I, Krupoves A, Feguery H, Dong J, Grimard G, Deslandres C, Levy E, Seidman EG. Interleukin 10 (IL-10) gene variants and susceptibility for pediatric onset Crohn's disease. Aliment Pharmacol Therap 2009; 29(9): 1025-1031.

Associations between ABCB1/MDR1 gene polymorphisms and Crohn's disease: A gene-wide study in a pediatric population - Krupoves A, Seidman EG, Mack D, Israel D, Morgan K, Lambrette P, Costea I, Deslandres C, Grimard G, Law L, Levy E, Amre D. Associations between ABCB1/MDR1 gene polymorphisms and Crohn's disease: A gene-wide study in a pediatric population. Inflamm Bowel Dis 2009; 15(6): 900-908.

Reliability and validity of adapted French Canadian version of Scoliosis Research Society Outcomes Questionnaire (SRS-22) in Quebec - Beauséjour M, Joncas J, Goulet L, Roy-Beaudry M, Parent S, Grimard G, Forcier M, Lauriault S, Labelle H. Reliability and validity of adapted French Canadian version of Scoliosis Research Society Outcomes Questionnaire (SRS-22) in Quebec. Spine 2009; 34(6): 623-628.

Investigation of reported associations between the 20q13 and 21q22 loci and pediatric-onset Crohn's disease in Canadian children - Amre D, Mack D, Morgan K, Fujiwara M, Israel D, Deslandres C, Seidman E, Lambrette P, Costea I, Krupoves A, Feguery H, Dong J, Grimard G, Levy E. Investigation of reported associations between the 20q13 and 21q22 loci and pediatric-onset Crohn's disease in Canadian children. Am J Gastroenterol 2009; 104(11): 2824-2828.

Texture analysis for automatic segmentation of intervertebral disks of scoliotic spines from MR images - Chevrefils C, Cheriet F, Aubin C-É, Grimard G. Texture analysis for automatic segmentation of intervertebral disks of scoliotic spines from MR images. IEEE T Inf Technol B 2009; 13(4): 608-620.

[Molecular and genetic aspects of idiopathic scoliosis. Blood test for idiopathic scoliosis] - Moreau A, Akoumé Ndong MY, Azeddine B, Franco A, Rompré PH, Roy-Gagnon M-H, Turgeon I, Wang D, Bagnall K, Poitras B, Labelle H, Rivard C-H, Grimard G, Ouellet J, Parent S, Moldovan F. [Molecular and genetic aspects of idiopathic scoliosis. Blood test for idiopathic scoliosis]. Orthopade 2009; 38(2): 114-6, 118-21.

Prospective validation and head-to-head comparison of 3 ankle rules in a pediatric population - Gravel J, Hedrei P, Grimard G, Gouin S. Prospective validation and head-to-head comparison of 3 ankle rules in a pediatric population. Ann Emerg Med 2009; 54(4): 534-540.e1.

Investigation of associations between the pregnane-X receptor gene (NR1I2) and Crohn's disease in Canadian children using a gene-wide haplotype-based approach - Amre D, Mack D, Israel D, Morgan K, Krupoves A, Costea I, Lambrette P, Grimard G, Deslandres C, Levy E, Seidman EG. Investigation of associations between the pregnane-X receptor gene (NR1I2) and Crohn's disease in Canadian children using a gene-wide haplotype-based approach. Inflamm Bowel Dis 2008; 14(9): 1214-1218.

Associations between genetic variants in the IL23R gene and early-onset Crohn’s disease. Results from a case-control and family-based study among Canadian children - Amre D, Mack D, Israel D, Morgan K, Lambrette P, Law L, Grimard G, Deslandres C, Krupoves A, Bucionis V, Costea I, Bissonauth V, Feguery H, D'Souza S, Levy E, Seidman EG. Associations between genetic variants in the IL23R gene and early-onset Crohn’s disease. Results from a case-control and family-based study among Canadian children. Am J Gastroenterol 2008; 103(3): 615-620.

Récents progrès dans l’étiopathogénie de la scoliose idiopathique de l’adolescent et nouveaux concepts moléculaires - Letellier K, Azeddine B, Blain S, Turgeon I, Wang DS, Samba Boiro M, Moldovan F, Labelle H, Poitras B, Rivard C-H, Grimard G, Parent S, Ouellet J, Lacroix G, Moreau A. Récents progrès dans l’étiopathogénie de la scoliose idiopathique de l’adolescent et nouveaux concepts moléculaires. Médecine Sciences 2007; 23(11): 910-916.

Previous head injury is a risk factor for subsequent head injury in children: a longitudinal cohort study - Swaine BR, Tremblay C, Platt RW, Grimard G, Zhang X, Pless IB. Previous head injury is a risk factor for subsequent head injury in children: a longitudinal cohort study. Pediatrics 2007; 119(4): 749-758.

Watershed segmentation of intervertebral disk and spinal canal from MR images - Chevrefils C, Cheriet F, Grimard G, Aubin C-É. Watershed segmentation of intervertebral disk and spinal canal from MR images. Dans: Kamel M (ed.). Image analysis & recognition (Lecture notes in computer science, Vol. 4633). Berlin / Heidelberg (Germany). Springer, 2007; 1017-1027.

Imbalances in dietary consumption of fatty acids, vegetables, and fruits are associated with risk for Crohn's disease in children - Amre D, D'Souza S, Morgan K, Seidman EG, Lambrette P, Grimard G, Israel D, Mack D, Ghadirian P, Deslandres C, Chotard V, Budai B, Law L, Levy E, Seidman EG. Imbalances in dietary consumption of fatty acids, vegetables, and fruits are associated with risk for Crohn's disease in children. Am J Gastroenterol 2007; 102(9): 2016-2025.

Biomechanical study of anterior spinal instrumentation configurations - Cloutier L, Aubin C-É, Grimard G. Biomechanical study of anterior spinal instrumentation configurations. Eur Spine J 2007; 16(7): 1039-1045.

Investigating the hygiene hypothesis as a risk factor in pediatric onset Crohn's disease: a case-control study - Amre D, Lambrette P, Law L, Krupoves A, Chotard V, Costea F, Grimard G, Israel D, Mack D, Seidman EG. Investigating the hygiene hypothesis as a risk factor in pediatric onset Crohn's disease: a case-control study. Am J Gastroenterol 2006; 101(5): 1005-1011.

Dépistage précoce de la scoliose idiopathique et nouvelles perspectives thérapeutiques - Moreau A, Azeddine B, Letellier K, Blain S, Turgeon I, Wang DS, Samba Boiro M, Moldovan F, Labelle H, Poitras B, Rivard C-H, Grimard G, Parent S, Ouellet J, Lacroix G. Dépistage précoce de la scoliose idiopathique et nouvelles perspectives thérapeutiques. Physiother Paediat Bull 2006; 18: 21-24.

A variability study of computerised sagittal spino-pelvic radiological measures of trunk balance - Berthonnaud E, Labelle H, Roussouly P, Grimard G, Vaz G, Dimnet J. A variability study of computerised sagittal spino-pelvic radiological measures of trunk balance. J Spinal Disord Techniques 2005; 18(1): 66-71.

Melatonin signaling dysfunction in adolescent idiopathic scoliosis - Moreau A, Wang DS, Forget S, Azeddine B, Angeloni D, Fraschini F, Labelle H, Poitras B, Rivard C-H, Grimard G. Melatonin signaling dysfunction in adolescent idiopathic scoliosis. Spine 2004; 29(16): 1772-1781.

New emerging role of melatonin in adolescent idiopathic scoliosis: implication of a melatonin signaling dysfunction in AIS etiopathogenesis - Moreau A, Wang DS, Forget S, Azeddine B, Labelle H, Poitras B, Rivard C-H, Grimard G. New emerging role of melatonin in adolescent idiopathic scoliosis: implication of a melatonin signaling dysfunction in AIS etiopathogenesis. Dans: Sawatsky BJ (ed). Research into Spinal Deformities V. The Netherlands. IOS Press, 2004; 43-46.

Évaluation d'une méthode clinique d'acquisition rapide de la géométrie 3D de colonnes vertébrales scoliotiques - Vaiton M, Dansereau J, Grimard G, Beauséjour M, Labelle H, de Guise JA. Évaluation d'une méthode clinique d'acquisition rapide de la géométrie 3D de colonnes vertébrales scoliotiques. Innov Technol Biol Med 2004; 25(3): 150-162.

Biomechanical study of different configurations for the anteror instrumentation of the scoliotic spine - Cloutier L, Aubin C-É, Grimard G. Biomechanical study of different configurations for the anteror instrumentation of the scoliotic spine. Dans: Sawatsky BJ (ed). Research into Spinal Deformities V. The Netherlands. IOS Press, 2004; 170-173.

Sclerotherapy in aneurysmal bone cysts in children: a review of 17 cases - Dubois J, Chigot V, Grimard G, Isler M, Garel L. Sclerotherapy in aneurysmal bone cysts in children: a review of 17 cases. Pediatr Radiol 2003; 33(6): 365-372.

The pediatric spine - Labelle H, Grimard G. The pediatric spine. Dans: Koval KJ (ed). Orthopaedic Knowledge Update 7. American Academy of Orthopaedic Surgeons, 2002; 581-592.

Relationships between strap tension, interface pressures and spine correction in brace treatment of scoliosis - Beauséjour M, Petit Y, Grimard G, Aubin C-É, Dansereau J, Labelle H. Relationships between strap tension, interface pressures and spine correction in brace treatment of scoliosis. Dans: Tanguy A, Peuchot B (eds). Research into Spinal Deformities III. Amsterdam, The Netherlands. IOS Press, 2002; 207-211.

Evolution of 3D deformities in adolescents with progressive idiopathic scoliosis - Villemure I, Aubin C-É, Grimard G, Dansereau J, Labelle H. Evolution of 3D deformities in adolescents with progressive idiopathic scoliosis. Dans: Grivas B (ed). Research into Spinal Deformities IV. IOS Press, 2002; 54-58.

Progression of vertebral and spinal three-dimensional deformities in adolescent idiopathic scoliosis: a longitudinal study - Villemure I, Aubin C-É, Grimard G, Dansereau J, Labelle H. Progression of vertebral and spinal three-dimensional deformities in adolescent idiopathic scoliosis: a longitudinal study. Spine 2001; 26(20): 2244-2250.

Évaluation du stress et des stratégies de coping de l'adolescent devant subir une chirurgie correctrice du rachis - Joncas J, Vandal S, Grimard G, Rivard C-H, Poitras B, Labelle H. Évaluation du stress et des stratégies de coping de l'adolescent devant subir une chirurgie correctrice du rachis. J Orthopédie 2000; 3(7): 297-301.

Back pain in patients with adolescent idiopathic scoliosis (AIS) - Joncas J, Labelle H, Poitras B, Duhaime M, Rivard C-H, Grimard G, LeBlanc R. Back pain in patients with adolescent idiopathic scoliosis (AIS). Dans: Sevastik JA, Diab KM (eds). Research into Spinal Deformities. IOS Press, 1998; 381-384.

Open fracture of the tibia in children - Grimard G, Naudie D, Caouette-Laberge L, Hamdy R. Open fracture of the tibia in children. Clin Orthop Relat R 1997; 332: 62-70.

Ski alpin: la prévention des blessures chez les enfants - Goulet C, Régnier G, Grimard G. Ski alpin: la prévention des blessures chez les enfants. L'Actualité médicale 1997; 18(35): 10-11.

Douleur dorsolombaire et scoliose idiopathique de l'adolescence - Joncas J, Labelle H, Poitras B, Duhaime M, Rivard C-H, Grimard G, LeBlanc R. Douleur dorsolombaire et scoliose idiopathique de l'adolescence. Ann Chir 1996; 50: 637-640.

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