Chercheuse ou chercheur

Titres

• Neurologue et épileptologue pédiatrique
• Professeur adjoint de clinique, Département de pédiatrie, Faculté de médecine, Université de Montréal, 2022
• Directeur de programme, formation complémentaire (fellowship) en épilepsie pédiatrique de l’Université de Montréal 
• Directeur, programme ECHO CHU Sainte-Justine Épilepsie pédiatrique.

• Formation complémentaire (fellowship) en épilepsie et neurophysiologie clinique pédiatrique, Boston Children’s Hospital, Harvard Medical School, 2021-2022
• Surspécialité en neurologie pédiatrique, SickKids, Université de Toronto, 2018-2021
• Certification en neurophysiologie, Société Canadienne de Neurophysiologie Clinique (SCNC), 2020
• Spécialité en pédiatrie, Montreal Children’s Hospital, Université McGill, 2014-2018
• Doctorat en médecine (M.D.), Université de Montréal, 2010-2014

• Épilepsie et neurophysiologie clinique
• Chirurgie de l’épilepsie
• Épilepsie réfractaire (pharmacorésistante)
• Connectomique
• Cerveau virtuel
• Intélligence artificielle et apprentissage automatique

Sommaire de carrière

Dr Aris Hadjinicolaou est un neurologue et épileptologue pédiatrique, diplômé en médecine de l’Université de Montréal. Il a complété sa résidence en pédiatrie à l’Université McGill, un fellowship en neurologie pédiatrique à l’Université de Toronto au SickKids’s Hospital, puis un fellowship en épilepsie et neurophysiologie clinique au Boston Children’s Hospital de l’Université Harvard.

Depuis 2022, il est co-responsable (avec le Dr Alexander Weil) du programme de chirurgie de l’épilepsie, co-responsable (avec les Drs Inge Meijer et Alexander Weil) du programme de neuromodulation, ainsi que directeur de programme de la formation complémentaire (fellowship) en épilepsie pédiatrique de l’Université de Montréal et directeur du programme ECHO CHU Sainte-Justine Épilepsie pédiatrique.

Dans le laboratoire qu’il co-dirige avec Dr Alexander Weil, sa recherche traite de l'épilepsie pédiatrique, de l'identification de facteurs prédictifs des effets post-chirurgie de l'épilepsie, de la découverte de nouveaux traitements et de l'application de nouvelles technologies en neurochirurgie de l’épilepsie, afin de rendre la chirurgie plus sécuritaire, efficace et d’améliorer la survie des patients.

Prix et distinctions

• Lauréat, Prix Hippocrate 2024, Catégorie émergent : Prix Innovation – Transformation de prestation de soins et services sociaux, Projet : Le programme de cartographie cérébrale et de neuromodulation compréhensive

Financement

• Associate Investigator
  • Décoder les crises au niveau cellulaire et circuitaire – une voie vers la médecine de précision pour les épilepsies réfractaires, projet partenaire CHUSJ-Centre Imagine intitule (total financing : 4 700 000 $)
• Co-Candidate
  • Thinking outside the (square) box: curved electrodes for deep brain recording and stimulation (total financing: 250 000 $)

Publications

• Margarita Maltseva, Juan Pablo Appendino, Pavlina Cabounova, Andrea Andrade, Michelle Kregel, Aris Hadjinicolaou, Alexander G. Weil, Puneet Jain, Elizabeth Donner, Felippe Borlot, David Dufresne, Linda Huh, Natarie Liu, Kenneth A. Myers, Julia Jacobs. Cortical Stimulation for brain mapping and seizure stimulation, pediatric practices throughout Canada: A national survey and systematic literature review. Neurophysiologie Clinique. Volume 55, Issue 2, 2025, 103043, ISSN 0987-7053, https://doi.org/10.1016/j.neucli.2025.103043.
• Jung Y, Mithani K, Suresh H, Warsi N, Harmsen IE, Breitbart S, Gorodetsky C, Fasano A, Fallah A, Hadjinicolaou A, Weil A, Ibrahim G. Deep brain stimulation in pediatric populations: A scoping review of the clinical trial landscape. Stereotact Funct Neurosurg. 2025 Jan 4:1-16. doi: 10.1159/000543289. Epub ahead of print. PMID: 39756376.
• Cottier R, Niazi F, Goël K, Korman C, Porte T, Ducruet T, Cossu G, Briscoe C, Singh A, Harini C, Ibrahim GM, Fallah A, Weil AG, Hadjinicolaou A. Outcomes following resective and disconnective strategies in the treatment of epileptic spasms: a systematic review of the literature and individual patient data meta-analysis. Front Neurol. 2024 Dec 30;15:1518554. doi: 10.3389/fneur.2024.1518554. PMID: 39807246; PMCID: PMC11726465.
• Spiegler P, Abdelsalam H, Hellum O, Hadjinicolaou A, Weil AG, Xiao Y. PreVISE: an efficient virtual reality system for SEEG surgical planning. Virtual Real. 2025;29(1):13. doi: 10.1007/s10055-024-01088-8. Epub 2024 Dec 26. PMID: 39735694; PMCID: PMC11669611.
• Niazi F, Goel K, Chen JS, Hadjinicolaou A, Keezer MR, Nguyen DK, Gallagher A, Shlobin N, Yuan-Mou Yang J, Soeby L, Webster E, Desnous B, Scavarda D, Perry MS, Mithani K, Ibrahim GM, Gaillard WD, Mathieu D, Kerrigan JF, Fallah A, Weil AG. Outcome of Surgery for Hypothalamic Hamartoma-Related Epilepsy: A Systematic Review and Individual Participant Data Meta-Analysis. Neurology. 2024 Dec 24;103(12):e210060. doi: 10.1212/WNL.0000000000210060. Epub 2024 Dec 6. PMID: 39642321.
• Aristides Hadjinicolaou, Mylène Dandavino, David D’Arienzo, Kimberley Kaspy, Elisa Ruano Cea, Implementing a resident-led transition-specific bootcamp curriculum during pediatric residency training: Our 3-year experience, Paediatrics & Child Health, 2024;, pxae077, https://doi.org/10.1093/pch/pxae077
• Yuan-Mou Yang J, Cottier R, Beare R, Genc S, Diadori P, Ngo A, Sahlas E, Bernhardt BC, Arbour G, Bouthillier A, Hadjinicolaou A, Weil AG. Advanced tractography-guided laser ablation of a perirolandic long-term epilepsy-associated tumor: illustrative case. J Neurosurg Case Lessons. 2024 Oct 7;8(15):CASE24139. doi: 10.3171/CASE24139. PMID: 39378521; PMCID: PMC11465345.
• Brunette-Clément T, Chang JW, Owens GC, Hadjinicolaou A, Weil AG, Fallah A. Brain Stiffness Correlates With Pathological Tissue in Patients With Drug-Resistant Epilepsy Due to Rasmussen Encephalitis and Focal Cortical Dysplasia. Oper Neurosurg (Hagerstown). 2024 Sep 27. doi: 10.1227/ons.0000000000001387. Epub ahead of print. PMID: 39329515.
• Dmytriw AA, Hadjinicolaou A, Ntolkeras G, Tamilia E, Pesce M, Berto LF, Grant PE, Pang E, Ahtam B. Magnetoencephalography for the pediatric population, indications, acquisition and interpretation for the clinician. Neuroradiol J. 2024 Jun 12:19714009241260801. doi: 10.1177/19714009241260801. Epub ahead of print. PMID: 38864180; PMCID: PMC11571317.
• Niazi F, Han A, Stamm L, Shlobin NA, Korman C, Hoang TS, Kielian A, Du Pont-Thibodeau G, Ducharme Crevier L, Major P, Nguyen DK, Bouthillier A, Ibrahim GM, Fallah A, Hadjinicolaou A, Weil AG. Outcome of emergency neurosurgery in patients with refractory and super-refractory status epilepticus: a systematic review and individual participant data meta-analysis. Front Neurol. 2024 May 28;15:1403266. doi: 10.3389/fneur.2024.1403266. PMID: 38863514; PMCID: PMC11165020.
• Hadjinicolaou A, Quinlan A, Liu S, Zhang B, Takeoka M, Sahin M, Prabhu SP, Pinto AL. Variation in neuroimaging and outcomes in patients with Sturge Weber syndrome Type III. Brain Dev. 2024 Aug;46(7):244-249. doi: 10.1016/j.braindev.2024.05.001. Epub 2024 May 12. PMID: 38740533.
• Major JD, Décarie JC, Ospina LH, Hadjinicolaou A. Absence of a Superior Colliculus Causing Gaze Deviation in a 6-Month-Old Boy: Case Report. Neurology. 2024 May;102(10):e209474. doi: 10.1212/WNL.0000000000209474. Epub 2024 May 1. PMID: 38687913.
• Ramani PK, Briscoe Abath C, Donatelli S, Hadjinicolaou A, Vega Toro S, Acevedo K, Astorga KR, Parbhoo K, Singh A, Catenaccio E, Jain P, Sahu JK, Samanta D, Harini C. Initial combination versus early sequential standard therapies for Infantile Epileptic Spasms Syndrome-Feedback from stakeholders. Epilepsia Open. 2024 Apr;9(2):819-822. doi: 10.1002/epi4.12895. Epub 2024 Jan 13. PMID: 38217384; PMCID: PMC10984285.
• Sheikh IS, Katyal R, Hadjinicolaou A, Bibby BM, Olandoski M, Nascimento FA, Beniczky S. The online educational tool "Roadmap to EEGs" significantly improved trainee performance in recognizing EEG patterns. Epileptic Disord. 2024 Aug;26(4):435-443. doi: 10.1002/epd2.20227. Epub 2024 Apr 30. PMID: 38687239.
• Katyal R, Sheikh IS, Hadjinicolaou A, Abath CB, Wirrell EC, Reddy SB, Beniczky S, Nascimento FA. Education Research: EEG Education in Child Neurology and Neurodevelopmental Disabilities Residencies: A Survey of US and Canadian Program Directors. Neurol Educ. 2024 Jan 5;3(1):e200112. doi: 10.1212/NE9.0000000000200112. PMID: 39360148; PMCID: PMC11441753.
• Goel K, Niazi F, Chen JS, Hadjinicolaou A, Keezer M, Gallagher A, Fallah A, Weil AG. Outcomes following surgical interventions for hypothalamic hamartomas: protocol for a systematic review and individual patient data meta-analysis. BMJ Open. 2024 Feb 12;14(2):e080870. doi: 10.1136/bmjopen-2023-080870
• Hadjinicolaou A, Briscoe Abath C, Singh A, Donatelli S, Salussolia CL, Li Cohen A, He J, Gupta N, Merchant S, Zhang B, Olson H, Yuskaitis CJ, Libenson MH, Harini C. Timing the clinical onset of epileptic spasms in infantile epileptic spasms syndrome: A tertiary health center's experience. Epilepsia, first published: 05 February 2024 https://doi.org/10.1111/epi.17900.
• Yoganathan S, Whitney R, Thomas M, Danda S, Chettali AM, Prasad AN, Farhan SMK, AlSowat D, Abukhaled M, Aldhalaan H, Gowda VK, Kinhal UV, Bylappa AY, Konanki R, Lingappa L, Parchuri BM, Appendino JP, Scantlebury MH, Cunningham J, Hadjinicolaou A, Moufawad El Achkar C, Kamate M, Menon RN, Jose M, Riordan G, Kannan L, Jain V, Manokaran RK, Chau V, Donner EJ, Costain G, Minassian BA, Jain P. KCTD7-related progressive myoclonic epilepsy: Report of 42 cases and review of literature. Epilepsia. First published: 17 January 2024 https://doi.org/10.1111/epi.17880
• Ramani PK, Briscoe Abath C, Donatelli S, Hadjinicolaou A, Vega Toro S, Acevedo K, Rosso Astorga K, Parbhoo K, Singh A, Catenaccio E, Jain P, Kumar Sahu J, Debopam S, Harini C. Initial combination versus early sequential standard therapies for Infantile Epileptic Spasms Syndrome—Feedback from stakeholders. Epilepsia Open. First published: 13 January 2024 https://doi.org/10.1002/epi4.12895.
• Briscoe Abath C, Gupta N, Hadjinicolaou A, Donatelli S, Singh A, Merchant S, Ryan ME, Soby M, Ryan C, Nelson AK, Maldonado Pacheco JE, Zhang B, Williams DN, Yuskaitis CJ, Harini C. Delays to Care in Infantile Epileptic Spasms Syndrome: Racial and Ethnic Inequities. Epilepsia. 12 novembre 2023. https://doi.org/10.1111/epi.17827
• Singh A, Hadjinicolaou A, Peters JM, Salussolia CL. Treatment-Resistant Epilepsy and Tuberous Sclerosis Complex: Treatment, Maintenance, and Future Directions. Neuropsychiatr Dis Treat. 2023;19:733-748. doi.org/10.2147/NDT.S347327
• Goel K, Pek V, Shlobin NA, Chen J-S, Wang A, Ibrahim GM; Hadjinicolaou A, Roessler K, Dudley RW, Nguyen DK, El-Tahry R, Fallah A, Weil AG. Clinical Utility of Intraoperative Electrocorticography for Epilepsy Surgery: A Systematic Review and Meta-Analysis. Epilepsia. 2023 Feb;64(2):253-265. doi: 10.1111/epi.17472. Epub 2022 Dec 12. PMID: 36404579.
• Sheikh IS, Katyal R, Hadjinicolaou A, Nascimento FA, Beniczky S. Roadmap to EEGs: video-based e-learning modules addressing clinical EEG reading. Epileptic Disord. 2022 Dec 1;24(6):1-7. doi: 10.1684/epd.2022.1495. PMID: 36266988.
• Sheikh IS, Katyal R, Hadjinicolaou A, Beniczky S, Nascimento FA. Introducing the Epileptic Disorders Internship Program. Epileptic Disord. 2022 Dec 1;24(6):1-2. English. doi: 10.1684/epd.2022.1485. PMID: 36125363.
• Hadjinicolaou A, Ngo KJ, Conway DY, Baker SK, Provias J, Brady L, Scherer S, Bennett C, La Spada A, Fogel BL, Yoon G. De Novo Pathogenic Variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe demyelinating polyneuropathy. ACCEPTÉ par Acta Neuropathologica Communications, octobre 2021.
• Hadjinicolaou A, Duan L, Kraus R, Lirette MP, Beck CE, Gardam M. "Call Me by My Name": Improving Communication with Family Members at the Bedside via the Caregiver Identification Badge. Healthc Q. 2021 Jan;23(4):60-64. doi: 10.12927/hcq.2020.26391. PMID: 33475494.
• Hadjinicolaou A, Jain P, Arya R, Roth C, Whitney R, Yau I, Greiner HM, Mangano FT, Rutka JT, Go C. Generator replacement with cardiac-based VNS device in children with T drug-resistant epilepsy: An observational study. [published online ahead of print, 2020 Jul 16]. Epilepsy Res. 2020;167:106431. doi:10.1016/j.eplepsyres.2020.106431
• Hadjinicolaou A, Ng P, Zhang X, Koclas L, Lamarre C, Malouin F, Pigeon N, Richards CL, Shevell M, Oskoui M. Is Cerebral Palsy Spectrum Disorder Changing in High Resource Settings? Data from the Quebec Cerebral Palsy Registry. J Child Neurol. 2019 May 10:883073819845272. doi: 10.1177/0883073819845272.