Chercheur

Titres

• Cheffe, Axe de recherche - Maladies infectieuses et soins aigu, CHU Sainte-Justine
• Pédiatre infectiologue 
• Professeure adjointe de clinique, Département de pédiatrie, Université de Montréal

Dre Fatima Kakkar a obtenu son doctorat en médecine à l’Université McGill (2003) et son diplôme de pédiatrie à l’Université de l’Est de l’Ontario (2007). Elle a par la suite poursuivi une formation complémentaire en maladies infectieuses pédiatriques et VIH de 3 ans à l’Hôpital Sick Children de Toronto. En 2011, Dre Kakkar a obtenu un Master of Public Health en recherche clinique de l’Université Harvard.

Sommaire de carrière

Dre Fatima Kakkar a joint le service des maladies infectieuses en 2011 et développe une carrière de recherche dans le domaine du VIH pédiatrique et des infections foeto-maternelles.

Domaines d’expertise

• VIH pédiatrique 
• Infections foeto-maternelles
• Épidémiologie 

Publications

1. Use of Cytomegalovirus-Specific Hyperimmunoglobulins in Pregnancy: A Retrospective Cohort.
   Minsart AF, Smiljkovic M, Renaud C, Gagné MP, Lamarre V, FATIMA KAKKAR, Boucher M, Boucoiran I.
   J Obstet Gynaecol Can. 2018 Jun 21. pii: S1701-2163(18)30124-5. doi: 10.1016/j.jogc.2018.03.013. [Epub ahead of print]
2. ARI BITNUN, TERRY LEE, JASON BROPHY, LINDY M. SAMSON, FATIMA KAKKAR, WENDY VAUDRY, BEN TAN, DEBORAH M. MONEY, JOEL SINGER, LAURA J. SAUVÉ, ARIANE ALIMENTI; for the Canadian Perinatal HIV Surveillance Program Missed opportunities for prevention of vertical HIV transmission in Canada, 1997–2016: a surveillance study.  CMAJ Open 2018. DOI:10.9778/cmajo.20180016
3. BUDD MA, CALLI K, SAMSON L, BOWES J, HSIEH AYY, FORBES JC, BITNUN A, SINGER J, KAKKAR F, ALIMENTI A, MAAN EJ, LEWIS MES, GENTILE C, CÔTÉ HCF, BROPHY JC. Blood Mitochondrial DNA Content in HIV-Exposed Uninfected Children with Autism Spectrum Disorder. Viruses. 2018 Feb 11;10(2).
4. AJAYKUMAR A, SOUDEYNS H, KAKKAR F, BROPHY J, BITNUN A, ALIMENTI A, ALBERT AYK, MONEY DM, CÔTÉ HCF; CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children (CARMA); CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children (CARMA).  Leukocyte telomere length at birth and during the early life of HIV-exposed uninfected children following in utero exposure to antiretrovirals. J Infect Dis. 2018 Feb 14;217(5):710-72
5. LAU E, BROPHY J, SAMSON L, KAKKAR F, CAMPBELL D, YUDIN MH, MURPHY K, SETO W, COLANTONIO D, READ SE, BITNUN A. Nevirapine Pharmacokinetics and Safety in Neonates Receiving Combination Antiretroviral Therapy for Prevention of Vertical HIV Transmission. J Acquir Immune Defic Syndr. 2017 Jan 20.
6. GANTT S, BITNUN A, RENAUD C, KAKKAR F, VAUDRY W. Diagnosis and management of infants with congenital CMV infection. Pediatric and Child Health. 2017 May;22(2):72-74. 
7. Zash RM, Williams PL, Sibiude J, Lyall H, Kakkar F.Surveillance monitoring for safety of in utero antiretroviral therapy exposures: current strategies and challenges. Expert Opin Drug Saf. 2016 Nov;15(11):1501-1513.
8. Ruck C, Reikie BA, Marchant A, Kollmann TR, Kakkar F. Linking Susceptibility to Infectious Diseases to Immune System Abnormalities among HIV-Exposed Uninfected Infants.Front Immunol. 2016 Aug 19;7:310. Review.
9. Kakkar F, Van der Linden D, Valois S, Maurice F, Onnorouille M, Lapointe N, Soudeyns H, Lamarre V. Health outcomes and the transition experience of HIV-infected adolescents after transfer to adult care in Québec, Canada..BMC Pediatr. 2016 Jul 26;16:109.
10. Wizman S, Lamarre V, Coic L, Kakkar F, Le Meur JB, Rousseau C, Boucher M, Tapiero B. Awareness of cytomegalovirus and risk factors for susceptibility among pregnant women, in Montreal, Canada. BMC Pregnancy Childbirth. 2016 Mar 15;16:54. 
11. Kakkar FW, Samson L, Vaudry W, Brophy J, Le Meur JB, Lapointe N, Read SE, Bitnun A. Safety of combination antiretroviral prophylaxis in high-risk HIV-exposed newborns: a retrospective review of the Canadian experience. J Int AIDS Soc. 2016 Feb 12;19(1):20520
12. Boucoiran I, Tulloch K, Pick N, Kakkar F, van Schalkwyk J, Money D, Boucher M. A case series of third-trimester raltegravir initiation: Impact on maternal HIV-1 viral load and obstetrical outcomes. Can J Infect Dis Med Microbiol. 2015 May-Jun;26(3):145-50.
13. Kakkar F, Boucoiran I, Lamarre V, Ducruet T, Amre D, Soudeyns H, Lapointe N, Boucher M. Risk factors for pre-term birth in a Canadian cohort of HIV-positive women: role of ritonavir boosting? J Int AIDS Soc. 2015 Jun 5;18:19933. doi: 10.7448/IAS.18.1.19933.
14. Rose W, Kitai I, Kakkar F, Read SE, Behr MA, Bitnun A. Quantiferon Gold-in-tube assay for TB screening in HIV infected children: influence of quantitative values. BMC Infect Dis. 2014 Sep 23;14:516.
15. Bitnun A, Samson L, Chun TW, Kakkar F, Brophy J, Murray D, Justement S, Soudeyns H, Ostrowski M, Mujib S, Harrigan PR, Kim J, Sandstrom P, Read SE. Early initiation of combination antiretroviral therapy in HIV-1-infected newborns can achieve sustained virologic suppression with low frequency of CD4+ T cells carrying HIV in peripheral blood. Clin Infect Dis. 2014 Oct;59(7):1012-9.
16. Kakkar F, Lamarre V, Ducruet T, Boucher M, Valois S, Soudeyns H, Lapointe N. Impact of maternal HIV-1 viremia on lymphocyte subsets among HIV-exposed uninfected infants: protective mechanism or immunodeficiency. BMC Infect Dis. 2014 May 5;14:236
17. Bitnun A, Brophy J, Samson L, Alimenti A, Kakkar F, Lamarre V, Moore D, Karatzios C, Seigel S, Sauve L, Vaudry W, Yudin MH, Money D. Prevention of vertical HIV transmission and management of the HIV-exposed infant in Canada in 2014. Can J Infect Dis Med Microbiol. 2014 Mar;25(2):75-7. 
18. Van der Linden D, Lapointe N, Kakkar F, Ransy DG, Motorina A, Maurice F, Soudeyns H, Lamarre V. The Young and the Resistant: HIV-infected Canadian adolescents at the time of transfer to adult care. J Ped Infect Dis Soc., 19 déc 2012: 1-4. 
19. Kakkar F, Allen U, Ling D Pai M, Kitail IW. Tuberculosis in children: New diagnostic blood tests.   Canadian Paediatric Society, Infectious Diseases and Immunization Committee. Tuberculosis in children: New diagnostic blood tests. Paediatrics & Child Health 2010;15(8):529-533. 
20. Salvadori M, Kakkar F, Sumpton J. A Canadian Perspective on the American Academy of Pediatrics Guidelines for Otitis Media.  Pediatrics & Child Health 2007; 12(7):579-81.
21.